Publications of Yvonne Genzel

Journal Article (102)

2013
Journal Article
Kluge, S., Rourou, S., Vester, D., Majoul, S., Benndorf, D., Genzel, Y., Rapp, E., Kallel, H., & Reichl, U. (2013)Proteome analysis of virus-host cell interaction: rabies virus replication in Vero cells in two different mediaApplied Microbiology and Biotechnology, 97 (12), 5493–5506doi: 10.1007/s00253-013-4939-1.
Journal Article
Peschel, B., Frentzel, S., Laske, T., Genzel, Y., & Reichl, U. (2013)Comparison of influenza virus yields and apoptosis-induction in an adherent and a suspension MDCK cell lineVaccine, 31 (48), 5693–5699doi: 10.1016/j.vaccine.2013.09.051.
Journal Article
Rehberg, M., Ritter, J. B., Genzel, Y., Flockerzi, D., & Reichl, U. (2013)The relation between growth phases, cell volume changes and metabolism of adherent cells during cultivationJournal of Biotechnology, 164 (4), 489–499doi: 10.1016/j.biotec.2013.01.018.
Journal Article
Rödig, J. V., Rapp, E., Bohne, J., Kampe, M., Kaffka, H., Bock, A., Genzel, Y., & Reichl, U. (2013)Impact of Cultivation Conditions on N-glycosylation of Influenza Virus A Hemagglutinin Produced in MDCK Cell CultureBiotechnology and Bioengineering, 110 (6), 1691–1703doi: 10.1002/bit.24834.
Journal Article
Tung, S., Shi, Y., Wong, K., Zhu, F., Gorczynski, R., Laister, R., Minden, M., Blechert, A.-K., Genzel, Y., Reichl, U., & Spaner, D. E. (2013)PPARalpha and fatty acid oxidation mediate glucocorticoid resistance in chronic lymphocytic leukemiaBlood, 122 (6), 969–980 doi: 10.1182/blood-2013-03-489468.
2012
Journal Article
Isken, B., Genzel, Y., & Reichl, U. (2012)Productivity, apoptosis, and infection dynamics of influenza A/PR/8 strains and A/PR/8-based reassortantsVaccine, 30 (35), 5253–5261doi: 10.1016/j.vaccine.2012.05.065.
Journal Article
Lohr, V., Genzel, Y., Jordan, I., Katinger, D., Mahr, S., Sandig, V., & Reichl, U. (2012)Live attenuated influenza viruses produced in a suspension process with avian AGE1.CR.pIX cellsBMC Biotechnology, 12, 79doi: 10.1186/1472-6750-12-79.
2011
Journal Article
Bock, A., Schulze-Horsel, J., Schwarzer, J., Rapp, E., Genzel, Y., & Reichl, U. (2011)High-density microcarrier cell cultures for influenza virus productionBiotechnology Progress, 27 (1), 241–250doi: 10.1002/btpr.539.
Journal Article
Janke, R., Genzel, Y., Händel, N., Wahl, A., & Reichl, U. (2011)Metabolic adaptation of MDCK cells to different growth conditions: Effects on catalytic activities of central metabolic enzymesBiotechnology and Bioengineering, 108 (11), 2691–2704doi: 10.1002/bit.23215.
Journal Article
Kalmbach, A., Bordas, R., Öncül, A., Thévenin, D., Genzel, Y., & Reichl, U. (2011)Experimental Characterization of Flow Conditions in 2- and 20-L Bioreactors with Wave-Induced MotionBiotechnology Progress, 27 (2), 402–409doi: 10.1002/btpr.516.
Journal Article
Rödig, J., Rapp, E., Djeljadini, S., Lohr, V., Genzel, Y., Jordan, I., Sandig, V., & Reichl, U. (2011)Impact of Influenza Virus Adaptation Status on HA N-Glycosylation Patterns in Cell Culture-Based Vaccine ProductionJournal of Carbohydrate Chemistry, 30 (4-6), 281–290doi: 10.1080/07328303.2011.604454.
Journal Article
Roedig, J., Rapp, E., Höper, D., Genzel, Y., & Reichl, U. (2011)Impact of Host Cell Line Adaptation on Quasispecies Composition and Glycosylation of Influenza A Virus HemagglutininPLoS One, 6 (12), e27989doi: 10.1371/journal.pone.0027989.
2010
Journal Article
Genzel, Y., Dietzsch, C., Rapp, E., Schwarzer, J., & Reichl, U. (2010)MDCK and Vero cells for influenza virus vaccine production: a one-to-one comparison up to lab-scale bioreactor cultivationApplied Microbiology and Biotechnology, 88 (2), 461–475doi: 10.1007/s00253-010-2742-9.
Journal Article
Heynisch, B., Frensing, T., Heinze, K., Seitz, C., Genzel, Y., & Reichl, U. (2010)Differential activation of host cell signaling pathways through infection with two variants of influenza A /Puerto Rico /8/34 (H1N1) in MDCK cellsVaccine, 28 (51), 8210–8218doi: 10.1016/j.vaccine.2010.07.076.
Journal Article
Janke, R., Genzel, Y., Freund, S., Wolff, M. W., Grammel, H., Rühmkorf, C., Seidemann, J., Wahl, A., & Reichl, U. (2010)Expression, purification, and characterization of a His6-tagged glycerokinase from Pichia farinosa for enzymatic cycling assays in mammalian cellsJournal of Biotechnology, 150 (3), 396–403doi: 10.1016/j.jbiotec.2010.09.963.
Journal Article
Janke, R., Genzel, Y., Wahl, A., & Reichl, U. (2010)Measurement of Key Metabolic Enzyme Activities in Mammalian Cells Using Rapid and Sensitive Microplate-Based AssaysBiotechnology and Bioengineering, 107 (3), 566–581doi: 10.1002/bit.22817.
Journal Article
Lohr, V., Genzel, Y., Behrendt, I., Scharfenberg, K., & Reichl, U. (2010)A new MDCK suspension line cultivated in a fully defined medium in stirred-tank and wave bioreactorVaccine, 28 (38), 6256–6264doi: 10.1016/j.vaccine.2010.07.004.
Journal Article
Öncül, A., Kalmbach, A., Genzel, Y., Reichl, U., & Thevenin, D. (2010)Characterization of flow conditions in 2 L and 20 L wave bioreactors using Computational Fluid Dynamics.Biotechnology Progress, 26 (1), 101–110doi: 10.1002/btpr.312.
Journal Article
Ritter, J., Wahl, A., Freund, S., Genzel, Y., & Reichl, U. (2010)Metabolic effects of influenza virus infection in cultured animal cells: Intra- and extracellular metabolite profilingBMC Systems Biology, 4, 61doi: 10.1186/1752-0509-4-61.
Journal Article
Vester, D., Pflugmacher, A., Hoffmann, D., Seitz, C., Heldt, S., Bettenbrock, K., Genzel, Y., & Reichl, U. (2010)Real-time RT-qPCR assay for the analysis of human influenza A virus transcription and replication dynamicsJournal of Virological Methods, 168 (1-2), 63–71doi: 10.1016/j.jviromet.2010.04.017.
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