Publications of Britta Peschel

Kluge, S., Genzel, Y., Laus, K., Serve, A., Pflugmacher, A., Peschel, B., Rapp, E., & Reichl, U. (2016)Ezrin and HNRNP expression correlate with increased virus release rate and early onset of virus-induced apoptosis of MDCK suspension cellsBiotechnology Journal, 11 (10), 1332–1342doi: 10.1002/biot.201600384.

Frensing, T., Pflugmacher, A., Bachmann, M., Peschel, B., & Reichl, U. (2014)Impact of defective interfering particles on virus replication and antiviral host response in cell culture-based influenza vaccine productionApplied Microbiology and Biotechnology, 98 (21), 8999–9008doi: 10.1007/s00253-014-5933-y.

Heldt, S., Frensing, T., Pflugmacher, A., Gröpler, R., Peschel, B., & Reichl, U. (2013)Multiscale Modeling of Influenza A Virus Infection Supports the Development of Direct-Acting AntiviralsPLoS Computational Biology, 9 (11), e1003372doi: 10.1371/journal.pcbi.1003372.

Müller, T., Dürr, R., Isken, B., Schulze-Horsel, J., Reichl, U., & Kienle, A. (2013)Distributed modeling of human influenza a virus-host cell interactions during vaccine productionBiotechnology and Bioengineering, 110 (8), 2252–2266doi: 10.1002/bit.24878.

Peschel, B., Frentzel, S., Laske, T., Genzel, Y., & Reichl, U. (2013)Comparison of influenza virus yields and apoptosis-induction in an adherent and a suspension MDCK cell lineVaccine, 31 (48), 5693–5699doi: 10.1016/j.vaccine.2013.09.051.

Isken, B., Genzel, Y., & Reichl, U. (2012)Productivity, apoptosis, and infection dynamics of influenza A/PR/8 strains and A/PR/8-based reassortantsVaccine, 30 (35), 5253–5261doi: 10.1016/j.vaccine.2012.05.065.

Seitz, C., Isken, B., Heynisch, B., Rettkowski, M., Frensing, T., & Reichl, U. (2012)Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host responseApplied Microbiology and Biotechnology, 93 (2), 601–611doi: 10.1007/s00253-011-3569-8.

Dürr, R., Müller, T., Isken, B., Schulze-Horsel, J., Reichl, U., & Kienle, A. (2012)Distributed Modeling and Parameter Estimation of Influenza Virus Replication During Vaccine ProductionIn: IFAC Proceedings Volumes, 320–325doi: 10.3182/20120215-3-AT-3016.00056.

Isken, B., Schulze-Horsel, J., Bock, A., Genzel, G., & Reichl, U. (2012)Monitoring of Host-Cell Infection and Virus-Induced Apoptosis in Influenza Vaccine ProductionIn: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), 675–683doi: 10.1007/978-94-007-0884-6_107.

Müller, T., Dürr, R., Isken, B., Schulze-Horsel, J., Reichl, U., & Kienle, A. (2011)Population balance modelling of influenza virus replication during vaccine prodcution - Influence of apoptosisIn: 21st European Symposium on Computer Aided Process Engineering - Part A, 1336–1340doi: 10.1016/B978-0-444-54298-4.50046-5.

Heldt, S., Isken, B., Pflugmacher, A., Frensing, T., & Reichl, U.Multi-scale modeling of influenza virus infection elucidates the performance of antiviralsPresented at: 1st Workshop on Virus Dynamics (DECHEMA)Frankfurt/Main, Germany, July 15, 2013.

Heldt, S., Peschel, B., Frensing, T., & Reichl, U.Multiscale modeling of influenza virus infection supports the development of antiviral drugsPresented at: 14th International Conference on Systems Biology Copenhagen (Denmark), August 30, 2013.

Dürr, R., Müller, T., Isken, B., Schulze-Horsel, J., Reichl, U., & Kienle, A.Distributed Modeling and Parameter Estimation of Influenza Virus Replication During Vaccine ProductionPresented at: MATHMOD 2012 - 7th Vienna International Conference on Mathematical ModellingVienna, Austria, February 14, 2012.

Genzel, Y., Janke, R., Isken, B., Rödig, J., Rapp, E., Lohr, V., Behrendt, I., Scharfenberg, K., Kamen, A., Schiedner, G., Jordan, I., & Reichl, U.Influenza virus production: characteristics of different producer cell linesPresented at: 10th PEACe 2011Cascais, Portugal, September 25, 2011.

Heldt, S., Isken, B., Pflugmacher, A., Frensing, T., & Reichl, U.A multi-scale model of influenza virus infection elucidates the performance of antiviralsPresented at: 23rd Annual Meeting of the Society for VirologyKiel, Germany, March 6, 2013.

Heldt, S., Peschel, B., Pflugmacher, A., Frensing, T., & Reichl, U.A multi-scale model of influenza virus infection elucidates the performance of antiviralsPresented at: 23rd Annual Meeting of the Society for Virology Kiel, Germany, March 6, 2013.

Kluge, S., Genzel, Y., Herche, K. C., Peschel, B., Pflugmacher, A., Rapp, E., Scharfenberg, K., & Reichl, U.Virus-Wirtszellinteraktionen einer adhärenten Zelllinie und ihrer adaptierten Suspensionszelllinie: Eine Proteom-StudiePresented at: Effiziente Verfahren und Anlagen in der Bioverfahrenstechnik und Lebensmittelbiotechnologie (Himmelfahrtstagung der DECHEMA 2013)Bad Wildungen, Germany, May 6, 2013.

Frensing, T., Seitz, C., Isken, B., Heynisch, B., Kochs, C., & Reichl, U.Influence of Host Cell Defence during Influenza Vaccine Production in Cell CulturePresented at: 22nd ESACT MeetingVienna, Austria, May 15, 2011.

Frensing, T., Seitz, C., Isken, B., Heynisch, B., Kochs, C., & Reichl, U.Influence of Host Cell Defence during Influenza Vaccine Production in Cell CulturePresented at: 22nd ESACT MeetingVienna, Austria, March 23, 2011.

Schulze-Horsel, J., Isken, B., Bock, A., Genzel, Y., & Reichl, U.Monitoring of host-cell infection and apoptosis in influenza vaccine productionPresented at: 21st ESACT MeetingDublin, Ireland, June 7, 2009.