Selected Articles

Here, we present selected publications and articles published by scientists of the MPI Magdeburg.


Speeding up Viedma Deracemization through Water‐catalyzed and Reactant Self‐catalyzed Racemization

The Cover Feature in ChemPhysChem, Volume 21, Issue 16, August 18, 2020, summarizes the results of a joint computational and experimental study demonstrating that faster racemization through water‐catalyzed enolization could result in faster deracemization of a scalemic slurry of a chiral hydrazine derivative.

This paper has been published with the project partners at Friedrich-Alexander University of Erlangen-Nürnberg as part of the CORE ITN Project by the European Union Horizon 2020 Research and Innovation Program.

Tortora, C.; Mai, C.; Cascella, F.; Mauksch, M.; Seidel-Morgenstern, A.; Lorenz, H.; Tsogoeva, S. B.: Speeding up Viedma Deracemization through Water catalyzed and Reactant Self‐catalyzed Racemization. ChemPhysChem 21 (16), pp. 1775 - 1787 (2020)

Preparative Chromatography

The third edition of this popular work is revised to include the latest developments in this fast-changing field. Its interdisciplinary approach elegantly combines the chemistry and engineering to explore the fundamentals and optimization processes involved.


The book starts with a short history of chromatography and outlines future developments. The focus is preparative chromatography i.e. to isolate and purify products in high quality and yield by optimal and cost‐effective processes. It is the aim to provide and develop access to chromatographic purification concepts through the eyes of both engineers and chemists. This includes the fundamentals of natural science and design of materials and functionalities as well as mathematical modeling, simulation and process design supplemented by process operation and plant design.

"This special volume is essential for chemists and engineers working in chemical and pharmaceutical industries, as well as for food technologies, due to the interdisciplinary nature of these preparative chromatographic processes." Advances in Food Sciences

Schmidt-Traub, H.; Schulte, M.; Seidel-Morgenstern, A. (Eds.): Preparative Chromatography. Wiley-VCH Verlag, Weinheim (2020), 609 pp.

Purification of Curcumin from Ternary Extract-Similar Mixtures of Curcuminoids in a Single Crystallization Step

Highlight on the Front Cover of Crystals 2020, 10(3), 206;

Cover of Crystals, Volume 10, Issue 3 (March 2020)
Curcumin and its derivatives demethoxycurcumin (DMC) and bis(demethoxy)curcumin (BDMC) are natural ingredients of the plant rhizome of Curcuma longa L. Together they are known as curcuminoids. Despite their strong similarity in molecular structure, their pharmacological activity and therapeutic effects can differ, which requires isolation of curcumin in pure state. In the article, crystallization-based separation of curcumin from extract-similar curcuminoid mixtures is studied. Based on solubility and supersolubility data of pure curcumin and curcumin in the initial mixture, seeded cooling crystallization procedures were derived using different solvents/solvent systems. As a result, crystalline curcumin of up to 99.4% purity, free of BDMC and depleted DMC content, was provided in a simple single crystallization step. Opportunities to further enhance total curcumin recovery by optimizing the crystallization strategy are highlighted.


Horosanskaia, E.; Yuan, L.; Seidel-Morgenstern, A.; Lorenz, H.: Purification of Curcumin from Ternary Extract-Similar Mixtures of Curcuminoids in a Single Crystallization Step. Crystals 10 (3), 206 (2020)
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