Publications of Erdmann Rapp

Arigoni-Affolter, I., Losfeld, M.-E., Hennig, R., Rapp, E., & Aebi, M. (2024)A hierarchical structure in the N-glycosylation process governs the N-glycosylation output: prolonged cultivation induces glycoenzymes expression variations that are reflected in the cellular N-glycome but not in the protein and site-specific glycoprofile of CHO cellsGlycobiology, 34 (8), cwae045doi: 10.1093/glycob/cwae045.

Böttinger, K., Regl, C., Schäpertöns, V., Rapp, E., Wohlschlager, T., & Huber, C. G. (2024)“Small is beautiful” – examining reliable determination of low- abundant therapeutic antibody glycovariantsJournal of Pharmaceutical Analysis, 14 (10), 100982doi: 10.1016/j.jpha.2024.100982.

Karsten, C. B., Buettner, F. F. R., Cajic, S., Nehlmeier, I., Roshani, B., Klippert, A., Sauermann, U., Stolte-Leeb, N., Reichl, U., Gerardy-Schahn, R., Rapp, E., Stahl-Hennig, C., & Pöhlmann, S. (2024)Macrophage- and CD4+ T cell-derived SIV differ in glycosylation, infectivity and neutralization sensitivityPLOS Pathogens, 20 (5), e1012190doi: 10.1371/journal.ppat.1012190.

Burock, R., Cajic, S., Hennig, R., Buettner, F. F. R., Reichl, U., & Rapp, E. (2023)Reliable N-Glycan Analysis–Removal of Frequently Occurring Oligosaccharide Impurities by Enzymatic DegradationMolecules, 28 (4), 1843doi: 10.3390/molecules28041843.

Cajic, S., Hennig, R., Grote, V., Reichl, U., & Rapp, E. (2023)Removable Dyes—The Missing Link for In-Depth N-glycan Analysis via Multi-Method ApproachesEngineering, 26, 132–150doi: 10.1016/j.eng.2023.02.016.

Hussnaetter, K. P., Palm, P., Pich, A., Franzreb, M., Rapp, E., & Elling, L. (2023)Strategies for Automated Enzymatic Glycan Synthesis (AEGS)Biotechnology Advances, 67, 108208doi: 10.1016/j.biotechadv.2023.108208.

Morticelli, L., Rossdam, C., Cajic, S., Böthig, D., Magdei, M., Tuladhar, S. R., Petersen, B., Fischer, K., Rapp, E., Korossis, S., Haverich, A., Schnieke, A., Niemann, H., Buettner, F. F. R., & Hilfiker, A. (2023)Genetic knockout of porcineGGTA1orCMAH/GGTA1is associated with the emergence of neo‐glycansXenotransplantation, 30 (4), e12804doi: 10.1111/xen.12804.

Trbojević-Akmačić, I., Vučković, F., Pribić, T., Vilaj, M., Černigoj, U., Vidič, J., Šimunović, J., Kępka, A., Kolčić, I., Klarić, L., Novokmet, M., Pučić-Baković, M., Rapp, E., Štrancar, A., Polašek, O., Wilson, J. F., & Lauc, G. (2023)Comparative analysis of transferrin and IgG N-glycosylation in two human populationsCommunications Biology, 6, 312doi: 10.1038/s42003-023-04685-6.

Wenzel, L., Hoffmann, M., Rapp, E., Rexer, T., & Reichl, U. (2023)Cell-free N-glycosylation of peptides using synthetic lipid-linked hybrid and complex N-glycansFrontiers in Molecular Biosciences, 10, 1266431doi: 10.3389/fmolb.2023.1266431.

Beimdiek, J., Hennig, R., Burock, R., Puk, O., Biskup, S., Rapp, E., Lesinski-Schiedat, A., Buettner, F. F. R., & Das, A. M. (2022)Serum N-glycomics of a novel CDG-IIb patient reveals aberrant IgG glycosylationGlycobiology, 32 (5), 380–390doi: 10.1093/glycob/cwac003.

Hinterholzer, A., Moises, J., Regl, C., Schwap, S., Rapp, E., Huber, C. G., & Schubert, M. (2022)Unambiguous identification of α-Gal epitopes in intact monoclonal antibodies by NMR spectroscopymAbs, 14 (1), 2132977doi: 10.1080/19420862.2022.2132977.

Hütte, H. J., Tiemann, B., Shcherbakova, A., Grote, V., Hoffmann, M., Povolo, L., Lommel, M., Strahl, S., Vakhrushev, S. Y., Rapp, E., Buettner, F. F. R., Halim, A., Imberty, A., & Bakker, H. (2022)A Bacterial Mannose Binding Lectin as a Tool for the Enrichment of C- and O-Mannosylated PeptidesAnalytical Chemistry, 94 (20), 7329–7338doi: 10.1021/acs.analchem.2c00742.

Lageveen-Kammeijer, G. S. M., Rapp, E., Chang, D., Rudd, P. M., Kettner, C., & Zaia, J. (2022)The minimum information required for a glycomics experiment (MIRAGE): reporting guidelines for capillary electrophoresisGlycobiology, 32 (7), 580–587doi: 10.1093/glycob/cwac021.

Tolonen, A. C., Beauchemin, N., Bayne, C., Li, L., Tan, J., Lee, J., Meehan, B. M., Meisner, J., Millet, Y., LeBlanc, G., Kottler, R., Rapp, E., Murphy, C., Turnbaugh, P. J., von Maltzahn, G., Liu, C. M., & van Hylckama Vlieg, J. E. T. (2022)Synthetic glycans control gut microbiome structure and mitigate colitis in miceNature Communications, 13 (1), 1244doi: 10.1038/s41467-022-28856-x.

Chuzel, L., Fossa, S. L., Boisvert, M. L., Cajic, S., Hennig, R., Ganatra, M. B., Reichl, U., Rapp, E., & Taron, C. H. (2021)Combining functional metagenomics and glycoanalytics to identify enzymes that facilitate structural characterization of sulfated N-glycansMicrobial Cell Factories, 20 (20), 162doi: 10.1186/s12934-021-01652-w.

Di Marco, F., Berger, T., Esser-Skala, W., Rapp, E., Regl, C., & Huber, C. G. (2021)Simultaneous Monitoring of Monoclonal Antibody Variants by Strong Cation-Exchange Chromatography Hyphenated to Mass Spectrometry to Assess Quality Attributes of Rituximab-Based BiotherapeuticsInternational Journal of Molecular Sciences, 22 (16), 9072doi: 10.3390/ijms22169072.

Eussen, S. R. B. M., Mank, M., Kottler, R., Hoffmann, X.-K., Behne, A., Rapp, E., Stahl, B., Mearin, M. L., & Koletzko, B. (2021)Presence and Levels of Galactosyllactoses and Other Oligosaccharides in Human Milk and Their Variation during Lactation and According to Maternal PhenotypeNutrients, 13 (7), 2324doi: 10.3390/nu13072324.

Feichtinger, R. G., Hüllen, A., Koller, A., Kotzot, D., Grote, V., Rapp, E., Hofbauer, P., Brugger, K., Thiel, C., Mayr, J. A., & Wortmann, S. B. (2021)A spoonful of L‐fucose—an efficient therapy for GFUS‐CDG, a new glycosylation disorderEmbo Molecular Medicine, 13 (9), e14332doi: 10.15252/emmm.202114332.

Gücüm, S., Sakson, R., Hoffmann, M., Grote, V., Becker, C., Pakari, K., Beedgen, L., Thiel, C., Rapp, E., Ruppert, T., Thumberger, T., & Wittbrodt, J. (2021)A patient-based medaka alg2 mutant as a model for hypo-N-glycosylationDevelopment, 148 (11), dev199385doi: 10.1242/dev.199385.

Kawahara, R., Chernykh, A., Alagesan, K., Bern, M., Cao, W., Chalkley, R. J., Cheng, K., Choo, M. S., Edwards, N., Goldman, R., Hoffmann, M., Hu, Y., Huang, Y., Kim, J. Y., Kletter, D., Liquet, B., Liu, M., Mechref, Y., Meng, B., Neelamegham, S., Nguyen-Khuong, T., Nilsson, J., Pap, A., Park, G. W., Parker, B. L., Pegg, C. L., Penninger, J. M., Phung, T. K., Pioch, M., Rapp, E., Sakalli, E., Sanda, M., Schulz, B. L., Scott, N. E., Sofronov, G., Stadlmann, J., Vakhrushev, S. Y., Woo, C. M., Wu, H.-Y., Yang, P., Ying, W., Zhang, H., Zhang, Y., Zhao, J., Zaia, J., Haslam, S. M., Palmisano, G., Yoo, J. S., Larson, G., Khoo, K.-H., Medzihradszky, K. F., Kolarich, D., Packer, N. H., & Thaysen-Andersen, M. (2021)Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysisNature Methods, 18, 1304–1316doi: 10.1038/s41592-021-01309-x.