Publications of Josef Schulze-Horsel

Müller, T., Dürr, R., Isken, B., Schulze-Horsel, J., Reichl, U., & Kienle, A. (2013)Distributed modeling of human influenza a virus-host cell interactions during vaccine productionBiotechnology and Bioengineering, 110 (8), 2252–2266doi: 10.1002/bit.24878.

Bock, A., Schulze-Horsel, J., Schwarzer, J., Rapp, E., Genzel, Y., & Reichl, U. (2011)High-density microcarrier cell cultures for influenza virus productionBiotechnology Progress, 27 (1), 241–250doi: 10.1002/btpr.539.

Bock, A., Möhler, L., Sann, H., Schulze-Horsel, J., Genzel, Y., & Reichl, U. (2009)Growth behaviour of number distributed adherent MDCK cells for optimization in large scale microcarrier culturesBiotechnology Progress, 25 (6), 1717–1731doi: 10.1002/btpr.262.

Schulze-Horsel, J., Schulze, M., Agalaridis, G., Genzel, Y., & Reichl, U. (2009)Infection dynamics and virus-induced apoptosis in cell culture-based influenza vaccine production – flow cytometry and mathematical modelingVaccine, 27 (20), 2712–2722doi: 10.1016/j.vaccine.2009.02.027.

Schulze-Horsel, J., Genzel, Y., & Reichl, U. (2008)Flow cytometric monitoring of influenza A virus infection in MDCK cells during vaccine productionBMC Biotechnology, 8, 45doi: 10.1186/1472-6750-8-45.

Sidorenko, Y., Antoniukas, L., Schulze-Horsel, J., & Reichl, U. (2008)Mathematical model of growth and heterologous hantavirus protein production of the recombinant yeast Saccharomyces cerevisiaeEngineering in Life Sciences, 8 (4), 399–414doi: 10.1002/elsc.200700018.

Sidorenko, Y., Schulze-Horsel, J., Voigt, A., Reichl, U., & Kienle, A. (2008)Stochastic Population Balance Modeling of Influenza Virus Replication in Vaccine Production ProcessesChemical Engineering Science, 63, 157–169doi: 10.1016/j.ces.2007.09.014.

Sidorenko, Y., Voigt, A., Schulze-Horsel, J., Reichl, U., & Kienle, A. (2008)Stochastic population balance modeling of influenza virus replication in vaccine production processes. II. Detailed description of the replication mechanismChemical Engineering Science, 63 (8), 2299–2304doi: 10.1016/j.ces.2007.12.034.

Dürr, R., Müller, T., Isken, B., Schulze-Horsel, J., Reichl, U., & Kienle, A. (2012)Distributed Modeling and Parameter Estimation of Influenza Virus Replication During Vaccine ProductionIn: IFAC Proceedings Volumes, 320–325doi: 10.3182/20120215-3-AT-3016.00056.

Isken, B., Schulze-Horsel, J., Bock, A., Genzel, G., & Reichl, U. (2012)Monitoring of Host-Cell Infection and Virus-Induced Apoptosis in Influenza Vaccine ProductionIn: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), 675–683doi: 10.1007/978-94-007-0884-6_107.

Müller, T., Dürr, R., Isken, B., Schulze-Horsel, J., Reichl, U., & Kienle, A. (2011)Population balance modelling of influenza virus replication during vaccine prodcution - Influence of apoptosisIn: 21st European Symposium on Computer Aided Process Engineering - Part A, 1336–1340doi: 10.1016/B978-0-444-54298-4.50046-5.

Schulze-Horsel, J., Schulze, M., Genzel, Y., & Reichl, U. (2010)Single-cell approach in influenza vaccine production: apoptosis and virus protein productionIn: Cells and Culture: Proceedings of the 20th ESACT Meeting, 25–28doi: 10.1007/978-90-481-3419-9_5.

Mueller, T., Schulze-Horsel, J., Sidorenko, Y., Reichl, U., & Kienle, A. (2008)Population balance modeling of influenza virus replication in MDCK cells during vaccine productionIn: 18th European Symposium on Computer Aided Process Engineering: ESCAPE 18, 133–138doi: 10.1016/S1570-7946(08)80027-2.

Genzel, Y., Schulze-Horsel, J., Möhler, L., Sidorenko, Y., & Reichl, U. (2007)Influenza Vaccines: Challenges in Mammalian Cell Culture TechnologyIn: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, 503–508doi: 10.1007/978-1-4020-5476-1_85.

Schulze-Horsel, J., Genzel, Y., & Reichl, U. (2007)Monitoring of Cell Physiology in Influenza Vaccine Production by Flow CytometryIn: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, 531–533doi: 10.1007/978-1-4020-5476-1_90.

Sidorenko, Y., Schulze-Horsel, J., Voigt, A., Reichl, U., & Kienle, A. (2006)Stochastic Population Balance Modeling of Influenza Virus replication in a Vaccine Production ProcessIn: Conference Proceedings / AIChE annual meeting 2006, 622f.

Dürr, R., Müller, T., Isken, B., Schulze-Horsel, J., Reichl, U., & Kienle, A.Distributed Modeling and Parameter Estimation of Influenza Virus Replication During Vaccine ProductionPresented at: MATHMOD 2012 - 7th Vienna International Conference on Mathematical ModellingVienna, Austria, February 14, 2012.

Genzel, Y., Kalbfuss, B., Ritter, J. B., Schulze-Horsel, J., Rapp, E., Vester, D., & Reichl, U.Characterization and analytical issues on an influenza A virus production processPresented at: Vaccines : Quality control, scale-up and manufactureHamburg, Germany, December 5, 2006.

Genzel, Y., Schulze-Horsel, J., & Reichl, U.High Cell Density Microcarrier Process in a Wave Bioreactor for the Production of Influenza A VirusPresented at: Vaccine TechnologyPuerto Vallarta, Mexiko, June 25, 2006.

Schulze-Horsel, J., Bock, A., Genzel, Y., & Reichl, U.Mammalian cell culture for influenza vaccine production: physiology during cell growth and virus propagation phasePresented at: GVC/DECHEMA-Jahrestagungen 2006 mit 24. DECHEMA-Jahrestagung der BiotechnologenWiesbaden, Germany, September 24, 2006.