Publications of Yvonne Genzel
All genres
Journal Article (105)
2025
Journal Article
, Göbel, S., , , , Genzel, Y., & (2025)Streamlining the purification of a clinical-grade oncolytic virus for therapeutic applicationsSeparation and Purification Technology, 354, 128769doi: 10.1016/j.seppur.2024.128769.
2024
Journal Article
Göbel, S., , , , , , , , Reichl, U., , & Genzel, Y. (2024)Parallel Multifactorial Process Optimization and Intensification for High-Yield Production of Live YF17D-Vectored Zika VaccineVaccines, 12 (7), 755doi: 10.3390/vaccines12070755.
Journal Article
Göbel, S., Pelz, L., , , , , , Reichl, U., & Genzel, Y. (2024)Production of recombinant vesicular stomatitis virus-based vectors by tangential flow depth filtrationApplied Microbiology and Biotechnology, 108 (1), 240doi: 10.1007/s00253-024-13078-6.
Journal Article
Pelz, L., Dogra, T., Marichal-Gallardo, P., , Hemissi, G., Kupke, S. Y., Genzel, Y., & Reichl, U. (2024)Production of antiviral “OP7 chimera” defective interfering particles free of infectious virusApplied Microbiology and Biotechnology, 108, 97doi: 10.1007/s00253-023-12959-6.
Journal Article
Zinnecker, T. M., , , , Reichl, U., & Genzel, Y. (2024)From single‐cell cloning to high‐yield influenza virus production – implementing advanced technologies in vaccine process developmentEngineering in Life Sciences, 24 (4), 2300245doi: 10.1002/elsc.202300245.
Journal Article
Zinnecker, T. M., Reichl, U., & Genzel, Y. (2024)Innovations in cell culture-based influenza vaccine manufacturing – from static cultures to high cell density cultivationsHuman Vaccines & Immunotherapeutics, 20 (1), 2373521doi: 10.1080/21645515.2024.2373521.
2023
Journal Article
Dogra, T., Pelz, L., , Küchler, J., , Marichal-Gallardo, P., , , , Benndorf, D., Genzel, Y., , Kupke, S. Y., & Reichl, U. (2023)Generation of “OP7 chimera” defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in miceScientific Reports, 13, 20936doi: 10.1038/s41598-023-47547-1.
Journal Article
Göbel, S., Jaén, K. E., Dorn, M., , , , Reichl, U., , & Genzel, Y. (2023)Process intensification strategies toward cell culture‐based high‐yield production of a fusogenic oncolytic virusBiotechnology and Bioengineering, 120 (9), 2639–2657doi: 10.1002/bit.28353.
Journal Article
Göbel, S., Jaén, K. E., , , , Reichl, U., & Genzel, Y. (2023)Characterization of a quail suspension cell line for production of a fusogenic oncolytic virusBiotechnology and Bioengineering, 120, 3335–3346doi: 10.1002/bit.28530.
Journal Article
, Kazenmaier, D., , Dogra, T., , Kupke, S. Y., , Genzel, Y., & Reichl, U. (2023)Production of retroviral vectors in continuous high cell density cultureApplied Microbiology and Biotechnology, 107, 5947–5961doi: 10.1007/s00253-023-12689-9.
Journal Article
, , Hein, M., Dogra, T., Kazenmaier, D., , Genzel, Y., & (2023)Novel suspension retroviral packaging cells generated by transposition using transposase encoding mRNA advance vector yields and enable production in bioreactorsFrontiers in Bioengineering and Biotechnology, 11, 1076524doi: 10.3389/fbioe.2023.1076524.
2022
Journal Article
Göbel, S., , , , , Reichl, U., , & Genzel, Y. (2022)Cell-line screening and process development for a fusogenic oncolytic virus in small-scale suspension culturesApplied Microbiology and Biotechnology, 106, 4945–4961doi: 10.1007/s00253-022-12027-5.
Journal Article
Küchler, J., Püttker, S., Lahmann, P., Genzel, Y., Kupke, S. Y., Benndorf, D., & Reichl, U. (2022)Absolute quantification of viral proteins during single-round replication of MDCK suspension cellsJournal of Proteomics, 259, 104544doi: 10.1016/j.jprot.2022.104544.
Journal Article
, Baldok, N., , , , Reichl, U., Genzel, Y., , & (2022)Human 3D Airway Tissue Models for Real-Time Microscopy: Visualizing Respiratory Virus SpreadingCells, 11 (22), 3634doi: 10.3390/cells11223634.
Journal Article
, , , , , , Reichl, U., , Genzel, Y., & (2022)High-Titer Hepatitis C Virus Production in a Scalable Single-Use High Cell Density BioreactorVaccines, 10 (2), 249doi: 10.3390/vaccines10020249.
Journal Article
Rodrigues Correia Ramos, J., Bissinger, T., Genzel, Y., & Reichl, U. (2022)Impact of Influenza A Virus Infection on Growth and Metabolism of Suspension MDCK Cells Using a Dynamic ModelMetabolites, 12 (3), 239doi: 10.3390/metabo12030239.
2021
Journal Article
Bissinger, T., Wu, Y., Marichal-Gallardo, P., Riedel, D., , Genzel, Y., , & Reichl, U. (2021)Towards integrated production of an influenza A vaccine candidate with MDCK suspension cellsBiotechnology and Bioengineering, 118 (10), 3996–4013doi: 10.1002/bit.27876.
Journal Article
Gränicher, G., , Göbel, S., , Marichal-Gallardo, P., Genzel, Y., & Reichl, U. (2021)A high cell density perfusion process for Modified Vaccinia virus Ankara production: process integration with inline DNA digestion and cost analysisBiotechnology and Bioengineering, 118 (12), 4720–4734doi: 10.1002/bit.27937.
Journal Article
Gränicher, G., Tapia, F., Behrendt, I., , Genzel, Y., & Reichl, U. (2021)Production of Modified Vaccinia Ankara Virus by Intensified Cell Cultures: A Comparison of Platform Technologies for Viral Vector ProductionBiotechnology Journal, 16 (1), e2000024doi: 10.1002/biot.202000024.
Journal Article
, , Marichal-Gallardo, P., , Genzel, Y., , , Kupke, S. Y., & Reichl, U. (2021)Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particlesBMC Biology, 19 (1), 91doi: 10.1186/s12915-021-01020-5.