Publications of Jan Küchler

Journal Article (6)

2024
Journal Article
Guzman Ruiz, L., Zollner, A. M., Hoxie, I., Küchler, J., Hausjell, C., Mesurado, T., Krammer, F., Jungbauer, A., Pereira Aguilar, P., Klausberger, M., & Grabherr, R. (2024)Enhancing NA immunogenicity through novel VLP designsVaccine, 42 (24), 126270doi: 10.1016/j.vaccine.2024.126270.
Journal Article
Rüdiger, D., Piasecka, J., Küchler, J., Pontes, C., Laske, T., Kupke, S. Y., & Reichl, U. (2024)Mathematical model calibrated to in vitro data predicts mechanisms of antiviral action of the influenza defective interfering particle “OP7”iScience, 27 (4), 109421doi: 10.1016/j.isci.2024.109421.
2023
Journal Article
Dogra, T., Pelz, L., Boehme, J. D., Küchler, J., Kershaw, O., Marichal-Gallardo, P., Baelkner, M., Hein, M. D., Gruber, A. D., Benndorf, D., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U. (2023)Generation of “OP7 chimera” defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in miceScientific Reports, 13, 20936doi: 10.1038/s41598-023-47547-1.
Journal Article
Küchler, J., Willenbücher, K., Reiß, E., Nuß, L., Conrady, M., Ramm, P., Schimpf, U., Reichl, U., Szewzyk, U., & Benndorf, D. (2023)Degradation Kinetics of Lignocellulolytic Enzymes in a Biogas Reactor Using Quantitative Mass SpectrometryFermentation, 9 (1), 67doi: 10.3390/fermentation9010067.
2022
Journal Article
Küchler, J., Püttker, S., Lahmann, P., Genzel, Y., Kupke, S. Y., Benndorf, D., & Reichl, U. (2022)Absolute quantification of viral proteins during single-round replication of MDCK suspension cellsJournal of Proteomics, 259, 104544doi: 10.1016/j.jprot.2022.104544.
Journal Article
Kuil, T., Yayo, J., Pechan, J., Küchler, J., & van Maris, A. J. A. (2022)Ethanol tolerance of Clostridium thermocellum: the role of chaotropicity, temperature and pathway thermodynamics on growth and fermentative capacityMicrobial Cell Factories, 21, 273doi: 10.1186/s12934-022-01999-8.

Talk (3)

2023
Talk
Küchler, J., Opitz, P., Rüdiger, D., Kupke, S. Y., Genzel, Y., Benndorf, D., & Reichl, U.Absolute quantification of influenza A virus proteins during single-round replication in different host cellsPresented at: 6th Workshop on Virus DynamicsNagoya (Japan), July 4, 2023.
Talk
Rüdiger, D., Küchler, J., Piasecka, J., Pontes, C., Kupke, S. Y., & Reichl, U.OP7, a defective interfering particle with mutations: in vitro infection experiments, intracellular model, impact of mutations and mode of antiviral actionPresented at: 6th Workshop on Virus DynamicsNagoya (japan), July 4, 2023.
2022
Talk
Rüdiger, D., Küchler, J., Pontes, C., Kupke, S. Y., & Reichl, U.Modeling the intracellular replication of a new type of defective interfering particle of influenza virus with genomic nucleotide substitutionsPresented at: 12th European Conference on Mathematical and Theoretical BiologyHeidelberg (Germany), September 19, 2022.

Poster (7)

2024
Poster
Küchler, J., Opitz, P., Jordan, I., Genzel, Y., Benndorf, D., & Reichl, U.Quantification of intracellular influenza A virus proteins shows changes in dynamics related to host cell line and virus seedPresented at: 28th ESACT Meeting Edingburgh (Scotland), June 23, 2024.
Poster
Küchler, J., Opitz, P., Jordan, I., Genzel, Y., Benndorf, D., & Reichl, U.Quantification of intracellular influenza A virus proteins shows changes in dynamics related to host cell line and virus seedPresented at: Himmelfahrtstagung on Bioprocess Engineering 2024Regensburg (Germany), May 6, 2024.
Poster
Piasecka, J., Rüdiger, D., Küchler, J., Kupke, S. Y., & Reichl, U.Mechanisms of antiviral action of the influenza defective interfering particle “OP7”Presented at: 33rd Annual Meeting of the Society for Virology (GfV)Vienna (Austria), March 25, 2023.
Poster
Piasecka, J., Rüdiger, D., Küchler, J., Kupke, S. Y., & Reichl, U.Mechanisms of antiviral action of the influenza defective interfering particle “OP7”Presented at: 28th ESACT MeetingEdinburgh (Scotland), June 23, 2024.
2023
Poster
Küchler, J., Opitz, P., Kupke, S. Y., Genzel, Y., Benndorf, D., & Reichl, U.Absolute quantification of viral proteins during single-round replication of vaccine producer cell linesPresented at: 32nd Annual Meeting of the Society for Virology (GfV) Ulm (Germany), March 28, 2023.
Poster
Küchler, J., Opitz, P., Kupke, S. Y., Genzel, Y., Benndorf, D., & Reichl, U.Absolute quantification of influenza A virus proteins during single-round replication in vaccine producer cell linesPresented at: 16th PEACe (Protein Expression in Animal Cells) ConferenceSitges (Spain), September 24, 2023.
2022
Poster
Küchler, J., Püttker, S., Lahmann, P., Genzel, Y., Kupke, S. Y., Benndorf, D., & Reichl, U.Absolute quantification of viral proteins during single-round replication of MDCK suspension cellsPresented at: Proteomic Forum 2022Leipzig (Germany), April 3, 2022.
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