Publications of Daniel Rüdiger

Rüdiger, D., Piasecka, J., Küchler, J., Pontes, C., Laske, T., Kupke, S. Y., & Reichl, U. (2024)Mathematical model calibrated to in vitro data predicts mechanisms of antiviral action of the influenza defective interfering particle “OP7”iScience, 27 (4), 109421doi: 10.1016/j.isci.2024.109421.

Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U. (2021)Semi-continuous propagation of influenza A virus and its defective interfering particles: analyzing the dynamic competition to select candidates for antiviral therapyJournal of Virology, 95 (24), e01174-21doi: 10.1128/JVI.01174-21.

Rüdiger, D., Pelz, L., Hein, M. D., Kupke, S. Y., & Reichl, U. (2021)Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culturePLoS Computational Biology, 17, e1009357doi: 10.1371/journal.pcbi.1009357.

Rüdiger, D., Kupke, S. Y., Laske, T., Zmora, P., & Reichl, U. (2019)Multiscale modeling of influenza A virus replication in cell cultures predicts infection dynamics for highly different infection conditionsPLoS Computational Biology, 15 (2), e1006819doi: 10.1371/journal.pcbi.1006819.

Rüdiger, D., Kupke, S. Y., & Reichl, U. (2018)A multiscale model of influenza A virus replication covering highly different infection conditions in cell culturesIn: IFAC-PapersOnLine, 32–33doi: 10.1016/j.ifacol.2018.09.026.

Pelz, L., Rüdiger, D., Hein, M., Böhme, J., Bälkner, M., Kershaw, O., Marichal-Gallardo, P., Gruber, A., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U.Engineered defective interfering particles of influenza A virus for antiviral treatmentPresented at: 33^rd Annual Meeting of the Society for Virology (GfV)Vienna (Austria), March 25, 2023.

Pelz, L., Rüdiger, D., Hein, M. D., Böhme, J., Bälkner, M., Kershaw, O., Marichal-Gallardo, P., Gruber, A., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U.Genetic engineering of Influenza A virus defective interfering particles towards improved antiviral efficacy and potential use as a live vaccinePresented at: Vaccine Technology IXLos Cabos (Mexico), May 19, 2024.

Rüdiger, D., Opitz, P., Kupke, S. Y., & Reichl, U.A two-dimensional model to predict influenza virus and defective interfering particle coinfection in tissue-like systemsPresented at: 28th ESACT MeetingEdingburgh (Scotland), June 23, 2024.

Rüdiger, D., Opitz, P., Kupke, S. Y., & Reichl, U.Predicting the antiviral efficacy of defective interfering particles against influenza virus infection in tissuesPresented at: KSMB-SMB 2024Seoul (South Korea), June 29, 2024.

Dogra, T., Pelz, L., Rüdiger, D., Kupke, S. Y., & Reichl, U.Reverse genetics for Influenza a virus to generate genetically engineered defective interfering particles for antiviral treatment and vaccinationPresented at: Vir-AI-DIP Workshop Hamburg (Germany), July 18, 2023.

Küchler, J., Opitz, P., Rüdiger, D., Kupke, S. Y., Genzel, Y., Benndorf, D., & Reichl, U.Absolute quantification of influenza A virus proteins during single-round replication in different host cellsPresented at: 6^th Workshop on Virus DynamicsNagoya (Japan), July 4, 2023.

Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. D., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Semi-continuous Propagation of Influenza A Virus and Its Defective Interfering Particles: Analyzing the Dynamic Competition To Select Candidates for Antiviral TherapyPresented at: Vir-AI-DIP WorkshopHamburg (Germany), July 18, 2023.

Rüdiger, D., Küchler, J., Piasecka, J., Pontes, C., Kupke, S. Y., & Reichl, U.OP7, a defective interfering particle with mutations: in vitro infection experiments, intracellular model, impact of mutations and mode of antiviral actionPresented at: 6^th Workshop on Virus DynamicsNagoya (japan), July 4, 2023.

Rüdiger, D., Pelz, L., Hein, M. D., Kupke, S. Y., & Reichl, U.Multiscale model of influenza A virus and defective interfering particle co-infection in animal cell culturePresented at: Vir-AI-DIP WorkshopHamburg (Germany), July 18, 2023.

Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Long-Term Propagation of Influenza A Virus and Its Defective Interfering Particles: Analyzing Dynamic Competition to Select Antiviral CandidatesPresented at: Vaccine Technology VIIISitges (Spain), June 12, 2022.

Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Semi-Continuous propagation of Influenza A virus and its defective interfering particles: Analyzing the dynamic competition to select antiviral candidatesPresented at: 27th ESACT MeetingLisbon (Portugal), June 26, 2022.

Rüdiger, D., Küchler, J., Pontes, C., Kupke, S. Y., & Reichl, U.Modeling the intracellular replication of a new type of defective interfering particle of influenza virus with genomic nucleotide substitutionsPresented at: 12th European Conference on Mathematical and Theoretical BiologyHeidelberg (Germany), September 19, 2022.

Rüdiger, D., Pelz, L., Hein, M. D., Kupke, S. Y., & Reichl, U.Multiscale model of influenza A virus and defective interfering particle co-infection in animal cell culturePresented at: 5th Workshop on Virus Dynamicsvirtual, October 4, 2021.

Pelz, L., Rüdiger, D., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Evolution and selection of influenza a virus defective interfering particles in a semi-continuous production system for the use as antiviralPresented at: The seventh ESWI Influenza ConferenceVirtual Meeting, December 6, 2020.

Rüdiger, D., Pelz, L., Hein, M., Kupke, S. Y., & Reichl, U.Multiscale model of DIP replication and its effects on influenza A virus infection in animal cell culturePresented at: Society for Mathematical Biology 2020 Annual MeetingVirtual Meeting, August 17, 2020.