Publications of Lars Pelz

Göbel, S., Pelz, L., Silva, C. A. T., Brühlmann, B., Hill, C., Altomonte, J., Kamen, A., Reichl, U., & Genzel, Y. (2024)Production of recombinant vesicular stomatitis virus-based vectors by tangential flow depth filtrationApplied Microbiology and Biotechnology, 108 (1), 240doi: 10.1007/s00253-024-13078-6.

Pelz, L., Dogra, T., Marichal-Gallardo, P., Hein, M. D., Hemissi, G., Kupke, S. Y., Genzel, Y., & Reichl, U. (2024)Production of antiviral “OP7 chimera” defective interfering particles free of infectious virusApplied Microbiology and Biotechnology, 108, 97doi: 10.1007/s00253-023-12959-6.

Dogra, T., Pelz, L., Boehme, J. D., Küchler, J., Kershaw, O., Marichal-Gallardo, P., Baelkner, M., Hein, M. D., Gruber, A. D., Benndorf, D., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U. (2023)Generation of “OP7 chimera” defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in miceScientific Reports, 13, 20936doi: 10.1038/s41598-023-47547-1.

Pelz, L., Piagnani, E., Marsall, P., Wynserski, N., Hein, M. D., Marichal-Gallardo, P., Kupke, S. Y., & Reichl, U. (2023)Broad-Spectrum Antiviral Activity of Influenza A Defective Interfering Particles against Respiratory Syncytial, Yellow Fever, and Zika Virus Replication In VitroViruses, 15 (9), 1872doi: 10.3390/v15091872.

Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U. (2021)Semi-continuous propagation of influenza A virus and its defective interfering particles: analyzing the dynamic competition to select candidates for antiviral therapyJournal of Virology, 95 (24), e01174-21doi: 10.1128/JVI.01174-21.

Rüdiger, D., Pelz, L., Hein, M. D., Kupke, S. Y., & Reichl, U. (2021)Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culturePLoS Computational Biology, 17, e1009357doi: 10.1371/journal.pcbi.1009357.

Göbel, S., Pelz, L., Reichl, U., & Genzel, Y. (2023)Upstream processing for viral vaccines - Process intensificationBioprocessing of Viral Vaccines137–174.

Pelz, L., Göbel, S., Jaen , K., Reichl, U., & Genzel, Y. (2023)Upstream processing for viral vaccines – General aspectsBioprocessing of Viral Vaccines79–136.

Bälkner, M., Jeron, A., Volckmar, J., Pelz, L., Dogra, T., Kupke, S. Y., & Bruder, D. (2023)Characterization of the local innate immune response after mucosal application of IAV Defective Interfering ParticlesIn: European Journal of Immunology, P339doi: 10.1002/eji.202370300.

Göbel, S., Pelz, L., Behrendt, I., Prömmel, M., Altomonte, J., Anderlei, T., Bürgin, T., Genzel, Y., & Reichl, U. (2022)Scale-Down of an Ortbital Shaken Bioreactor: High Cell Density Cultivation in Perfusion Mode and Virus productionIn: Proceedings Single-Use Technologies V: Building the Future, 40.

Pelz, L., Rüdiger, D., Hein, M., Böhme, J., Bälkner, M., Kershaw, O., Marichal-Gallardo, P., Gruber, A., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U.Engineered defective interfering particles of influenza A virus for antiviral treatmentPresented at: 33^rd Annual Meeting of the Society for Virology (GfV)Vienna (Austria), March 25, 2023.

Pelz, L., Rüdiger, D., Hein, M. D., Böhme, J., Bälkner, M., Kershaw, O., Marichal-Gallardo, P., Gruber, A., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U.Genetic engineering of Influenza A virus defective interfering particles towards improved antiviral efficacy and potential use as a live vaccinePresented at: Vaccine Technology IXLos Cabos (Mexico), May 19, 2024.

Dogra, T., Pelz, L., Boehme, J. D., Baelkner, M., Kershaw, O., Marichal-Gallardo, P., Gruber, A. D., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U.Genetically engineered defective interfering particles of influenza A virus for antiviral treatment and vaccinationPresented at: 17^th Vaccine CongressGlasgow (Scotland), September 24, 2023.

Dogra, T., Pelz, L., Rüdiger, D., Kupke, S. Y., & Reichl, U.Reverse genetics for Influenza a virus to generate genetically engineered defective interfering particles for antiviral treatment and vaccinationPresented at: Vir-AI-DIP Workshop Hamburg (Germany), July 18, 2023.

Göbel, S., Jaén, K. E., Pelz, L., Reiter , M., Altomonte, J., Reichl, U., & Genzel, Y.Intensifiying OSB processes for high titer virus productionPresented at: 5^th large scale meeting: Orbital shaken bioreactorsGirona (Spain), June 5, 2023.

Kupke, S. Y., Dogra, T., Pelz, L., Hein, M. D., Ndeir, N., Rand, U., Boehme, J., Baelkner, M., Kershaw, O., Winkler, M., Cicin-Sain, L., Bruder, D., Pöhlmann, S., & Reichl, U.Influenza A virus defective interfering particles as antiviral agentsPresented at: 32^nd Annual Meeting of the Society for Virology (GfV)Ulm (Germany), March 28, 2023.

Pelz, L., Dogra, T., Boehme, J. D., Hein, M. D., Marichal-Gallardo, P., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U.Influenza A virus OP7 defective interfering particles: Cell culture-based production and antiviral efficacy in vivoPresented at: Cell Culture Engineering (CCE) XVIII Cancun (Mexico), April 23, 2023.

Pelz, L., Genzel, Y., Kupke, S. Y., & Reichl, U.In-depth characterization and cell culture-based production of influenza A virus defective interfering particlesPresented at: ACTIP fellowship sessionDublin (Ireland), October 11, 2023.

Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. D., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Semi-continuous Propagation of Influenza A Virus and Its Defective Interfering Particles: Analyzing the Dynamic Competition To Select Candidates for Antiviral TherapyPresented at: Vir-AI-DIP WorkshopHamburg (Germany), July 18, 2023.

Rüdiger, D., Pelz, L., Hein, M. D., Kupke, S. Y., & Reichl, U.Multiscale model of influenza A virus and defective interfering particle co-infection in animal cell culturePresented at: Vir-AI-DIP WorkshopHamburg (Germany), July 18, 2023.