Publications of Lars Pelz

Journal Article (3)

2023
Journal Article
Pelz, L., Piagnani, E., Marsall, P., Wynserski, N., Hein, M. D., Marichal-Gallardo, P., Kupke, S. Y., & Reichl, U. (2023)Broad-Spectrum Antiviral Activity of Influenza A Defective Interfering Particles against Respiratory Syncytial, Yellow Fever, and Zika Virus Replication In VitroViruses, 15 (9), 1872doi: 10.3390/v15091872.
2021
Journal Article
Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U. (2021)Semi-continuous propagation of influenza A virus and its defective interfering particles: analyzing the dynamic competition to select candidates for antiviral therapyJournal of Virology, 95 (24), e01174-21doi: 10.1128/JVI.01174-21.
Journal Article
Rüdiger, D., Pelz, L., Hein, M. D., Kupke, S. Y., & Reichl, U. (2021)Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culturePLoS Computational Biology, 17, e1009357doi: 10.1371/journal.pcbi.1009357.

Book Chapter (2)

2023
Book Chapter
Göbel, S., Pelz, L., Reichl, U., & Genzel, Y. (2023)Upstream processing for viral vaccines - Process intensificationBioprocessing of Viral Vaccines137–174.
Book Chapter
Pelz, L., Göbel, S., Jaen , K., Reichl, U., & Genzel, Y. (2023)Upstream processing for viral vaccines – General aspectsBioprocessing of Viral Vaccines79–136.

Meeting Abstract (1)

2022
Meeting Abstract
Göbel, S., Pelz, L., Behrendt, I., Prömmel, M., Altomonte, J., Anderlei, T., Bürgin, T., Genzel, Y., & Reichl, U. (2022)Scale-Down of an Ortbital Shaken Bioreactor: High Cell Density Cultivation in Perfusion Mode and Virus productionIn: Proceedings Single-Use Technologies V: Building the Future, 40.

Talk (6)

2022
Talk
Göbel, S., Pelz, L., Behrendt, I., Prömmel, M., Altomonte, J., Anderlei, T., Bürgin, T., Genzel, Y., & Reichl, U.Scale-Down of an Ortbital Shaken Bioreactor: High Cell Density Cultivation in Perfusion Mode and Virus productionPresented at: Single-Use Technologies V: Building the FutureMarseille, France, March 20, 2022.
Talk
Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Long-Term Propagation of Influenza A Virus and Its Defective Interfering Particles: Analyzing Dynamic Competition to Select Antiviral CandidatesPresented at: Vaccine Technology VIIISitges (Spain), June 12, 2022.
Talk
Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Semi-Continuous propagation of Influenza A virus and its defective interfering particles: Analyzing the dynamic competition to select antiviral candidatesPresented at: 27th ESACT MeetingLisbon (Portugal), June 26, 2022.
2021
Talk
Rüdiger, D., Pelz, L., Hein, M. D., Kupke, S. Y., & Reichl, U.Multiscale model of influenza A virus and defective interfering particle co-infection in animal cell culturePresented at: 5th Workshop on Virus Dynamicsvirtual, October 4, 2021.
2020
Talk
Pelz, L., Rüdiger, D., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Evolution and selection of influenza a virus defective interfering particles in a semi-continuous production system for the use as antiviralPresented at: The seventh ESWI Influenza ConferenceVirtual Meeting, December 6, 2020.
Talk
Rüdiger, D., Pelz, L., Hein, M., Kupke, S. Y., & Reichl, U.Multiscale model of DIP replication and its effects on influenza A virus infection in animal cell culturePresented at: Society for Mathematical Biology 2020 Annual MeetingVirtual Meeting, August 17, 2020.

Poster (4)

2022
Poster
Dogra, T., Pelz, L., Marc, H., Rüdiger, D., Boehme, J., Bruder, D., Kupke, S. Y., & Reichl, U.Reverse genetics for Influenza A virus to generate genetically engineered defective interfering particles for antiviral treatment and vaccinationPresented at: 27th ESACT MeetingLisbon (Portugal), June 26, 2022.
Poster
Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Long-Term Propagation of Influenza A Virus and Its Defective Interfering Particles: Analyzing Dynamic Competition to Select Antiviral CandidatesPresented at: Vaccine Technology VIIISitges (Spain), June 12, 2022.
Poster
Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Semi-Continuous propagation of Influenza A virus and its defective interfering particles: Analyzing the dynamic competition to select antiviral candidatesPresented at: 27th ESACT MeetingLisbon (Portugal), June 26, 2022.
2021
Poster
Pelz, L., Rüdiger, D., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Semi-continuous propagation of influenza A virus and its defective interfering particles - analyzing the dynamic competition to select antiviral candidatesPresented at: 30th Annual Meeting of the Society for Virologyonline, March 24, 2021.

Thesis - Master (1)

2019
Thesis - Master
Pelz, L. (2019)Optimization of yellow fever virus production with BHK-21 cellsMaster's Thesis, Technische Universität, München.

Preprint (2)

2021
Preprint
Pelz, L., Rüdiger, D., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U. (2021)Semi-continuous propagation of influenza A virus and its defective interfering particles: analyzing the dynamic competition to select candidates for antiviral therapybioRxivdoi: 10.1101/2021.02.08.430251 .
Preprint
Prerna , A., Bdeir, N., Gärtner, S., Reiter, S., Pelz, L., Felgenhauer, U., Reichl, U., Ludwig, S., Weber, F., Hoffmann, M., Winkler, M., & Pöhlmann , S. (2021)Interferon induction and not replication interference mainly determines anti-influenza virus activity of defective interfering particlesbioRxivdoi: 10.1101/2021.09.20.461172 .
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