Publications of Gwendal Gränicher

Gränicher, G., Babakhani, M., Göbel, S., Jordan, I., Marichal-Gallardo, P., Genzel, Y., & Reichl, U. (2021)A high cell density perfusion process for Modified Vaccinia virus Ankara production: process integration with inline DNA digestion and cost analysisBiotechnology and Bioengineering, 118 (12), 4720–4734doi: 10.1002/bit.27937.

Gränicher, G., Tapia, F., Behrendt, I., Jordan, I., Genzel, Y., & Reichl, U. (2021)Production of Modified Vaccinia Ankara Virus by Intensified Cell Cultures: A Comparison of Platform Technologies for Viral Vector ProductionBiotechnology Journal, 16 (1), e2000024doi: 10.1002/biot.202000024.

Coronel, J., Gränicher, G., Sandig, V., Noll, T., Genzel, Y., & Reichl, U. (2020)Application of an Inclined Settler for Cell Culture-Based Influenza A Virus Production in Perfusion ModeFrontiers in Bioengineering and Biotechnology, 8, 672doi: 10.3389/fbioe.2020.00672.

Gränicher, G., Coronel, J., Trampler, F., Jordan, I., Genzel, Y., & Reichl, U. (2020)Performance of an Acoustic Settler Versus a Hollow Fiber-Based ATF Technology for Influenza Virus Production in PerfusionApplied Microbiology and Biotechnology, 104 (11), 4877–4888doi: 10.1007/s00253-020-10596-x.

Gränicher, G., Coronel, J., Pralow, A., Marichal-Gallardo, P., Wolff, M. W., Rapp, E., Karlas, A., Sandig, V., Genzel, Y., & Reichl, U. (2019)Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG.PK2.1Vaccine, 37 (47), 7019–7028doi: 10.1016/j.vaccine.2019.04.030.

Nikolay, A., Bissinger, T., Gränicher, G., Wu, Y., Genzel, Y., & Reichl, U. (2020)Perfusion Control for High Cell Density Cultivation and Viral Vaccine ProductionAnimal Cell Biotechnology141–168New York: Humanadoi: 10.1007/978-1-0716-0191-4_9.

Gränicher, G., Genzel, Y., Reichl, U., John, K., Sandig, V., & Karlas, A. (2018)A new porcine suspension cell line (PBG.PK-21) provides efficient production for influenza and yellow fever vaccine virusesIn: Vaccine Technology VII, 48.

Gränicher, G., Göbel, S., Marichal-Gallardo, P., Jordan, I., Sandig, V., Genzel, Y., & Reichl, U.Integrated cell-culture based MVA virus production process with perfusion mode for vaccines or gene therapyPresented at: Value through intensified bioprocessing IIOxford, United Kingdom, June 22, 2022.

Gränicher, G., Göbel, S., Marichal-Gallardo, P., Jordan, I., Sandig, V., Genzel, Y., & Reichl, U.Integrated cell-culture based MVA virus production process with perfusion mode for vaccines or gene therapyPresented at: 27th ESACT MeetingLisbon (Portugal), June 26, 2022.

Gränicher, G. (2021)Process intensification and integration for the production of vaccines and viral vectorsPhD Thesis, Otto-von-Guericke-Universität, Magdeburgdoi: 10.25673/66077.