Publications of Alexander Nikolay

Pralow, A., Nikolay, A., Leon, A., Genzel, Y., Rapp, E., & Reichl, U. (2021)Site-specific N-glycosylation analysis of animal cell culture-derived Zika virus proteinsScientific Reports, 11 (1), 5147doi: 10.1038/s41598-021-84682-z.

Nikolay, A., de Grooth, J., Genzel, Y., Wood, J. A., & Reichl, U. (2020)Virus harvesting in perfusion culture: Choosing the right typeof hollow fiber membraneBiotechnology and Bioengineering, 117 (10), 3040–3052doi: 10.1002/bit.27470.

Nikolay, A., Casthilho, L. R., Reichl, U., & Genzel, Y. (2018)Propagation of Brazilian Zika virus strains in static and suspension cultures using Vero and BHK cellsVaccine, 36 (22), 3140–3145doi: 10.1016/j.vaccine.2017.03.018.

Nikolay, A., Léon, A., Schwamborn, K., Genzel, Y., & Reichl, U. (2018)Process intensification of EB66 ^® cell cultivations leads to high-yield yellow fever and Zika virus productionApplied Microbiology and Biotechnology, 102 (20), 8725–8737doi: 10.1007/s00253-018-9275-z.

Gallo Ramirez, L. E., Nikolay, A., Genzel, Y., & Reichl, U. (2015)Bioreactor concepts for cell culture-based viral vaccine productionExpert Review of Vaccines, 14 (9), 1181–1191doi: 10.1586/14760584.2015.1067144.

Nikolay, A., Bissinger, T., Gränicher, G., Wu, Y., Genzel, Y., & Reichl, U. (2020)Perfusion Control for High Cell Density Cultivation and Viral Vaccine ProductionAnimal Cell Biotechnology141–168New York: Humanadoi: 10.1007/978-1-0716-0191-4_9.

Nikolay, A., Genzel, Y., Schwamborn, K., Leon, A., & Reichl, U. (2018)Flavivirus production in perfusion processes using the EB66® cell lineIn: Vaccine Technology VII, 80.

Reichl, U., Vazquez-Ramirez, D., Tapia, F., Nikolay, A., & Genzel, Y.Cell Culture-based Viral Vaccines: Process Intensification and MonitoringPresented at: Plenarsitzung der Sächischen Akademie der Wissenschaften zu LeipzigLeipzig, Germany, November 13, 2020.

Nikolay, A., Tapia, F., Marichal-Gallardo, P., Pralow, A., Hoffmann, M., Rapp, E., Genzel, Y., & Reichl, U.Moderne Methoden der ImpfstoffherstellungPresented at: Wissenschaft im RathausMagdeburg, Germany, September 30, 2019.

Nikolay, A., Tapia, F., Marichal-Gallardo, P., Pralow, A., Hoffmann, M., Rapp, E., Genzel, Y., & Reichl, U.Cell Culture-based Viral Vaccines: Process Intensification and MonitoringPresented at: Cuba Symposium “Frontiers of Science”Havanna, Cuba, March 5, 2019.

Reichl, U., Vazquez-Ramirez, D., Tapia, F., Nikolay, A., Genzel, Y., & Rapp, E.Process Intensification in Viral Vaccine ManufacturingPresented at: International Symposium on Pharmaceutical Engineering Research – SPhEReBraunschweig, Germany, September 25, 2019.

Nikolay, A.Stable animal cell growth in perfusion processes: Using on-line permittivity sensors to control cell-specific perfusion ratesPresented at: 5th BioProScale SymposiumBerlin, Germany, March 20, 2018.

Nikolay, A.Cell-culture-based perfusion processes for Flavivirus productionPresented at: 5th Laupheim Biotech DaysLaupheim, Germany, September 20, 2018.

Nikolay, A., Genzel, Y., & Reichl, U.Process intensification – Yellow fever virus and Zika virus production in suspension cellsPresented at: 13th PEACe Conference: Conference on Protein Expression in Animal CellsValencia, Spain, September 24, 2017.

Vazquez-Ramirez, D., Nikolay, A., Behrendt, I., Jordan, I., Bürgin, T., Genzel, Y., & Reichl, U.High-cell-density cultivations by hollow fiber-based perfusion for intensified viral vaccine productionPresented at: VII SLATCC meeting Cocoyoc, Morelos, Mexico, November 3, 2016.

Nikolay, A.CCE: The EB66 ^(R) Cell line for Yellow Fever Vaccine procustion at high cell concentrationsPresented at: Cell Culture Engineering XVITampa, Florida, USA, May 6, 2018.

Nikolay, A.Flavivirus production in perfusion processes using the EB66 ^(R) Cell linePresented at: Vaccine Technology VIIMont Tremblant, Canada, June 17, 2018.

Nikolay, A., Castilho, L., Genzel, Y., & Reichl, U.Process intensification of yellow fever virus and Zika virus production by perfusion bioreactorsPresented at: 25th ESACT MeetingLausanne, Switzerland, May 14, 2017.

Nikolay, A., Castilho, L., Genzel, Y., & Reichl, U.Production of yellow fever virus and Zika virus in perfusion bioreactorsPresented at: DECHEMA Himmelfahrtstagung "Models for Developing and Optimising Biotech Production"Neu-Ulm, Germany, May 22, 2017.

Nikolay, A., Castilho, L., Tanuri, A., Reichl, U., & Genzel, Y.Propagation of Brazilian Zika virus strains in static, microcarrier-based and suspension cultures using BHK and Vero cellsPresented at: 1st ESACT Frontiers Retreat 2016Lyon, France, October 20, 2016.