Publications of Daniel Vazquez-Ramirez

Vazquez-Ramirez, D., Jordan, I., Sandig, V., Genzel, Y., & Reichl, U. (2019)High titer MVA and influenza A virus production using a hybrid fed-batch/perfusion strategy with an ATF systemApplied Microbiology and Biotechnology, 103 (7), 3025–3035doi: 10.1007/s00253-019-09694-2.

Vazquez-Ramirez, D., Genzel, Y., Jordan, I., Sandig, V., & Reichl, U. (2018)High-cell-density cultivations to increase MVA virus productionVaccine, 36 (22), 3124–3133doi: 10.1016/j.vaccine.2017.10.112.

Genzel, Y., Vogel, T., Buck, J., Behrendt, I., Vazquez-Ramirez, D., Schiedner, G., Jordan, I., & Reichl, U. (2014)High cell density cultivations by alternating tangential flow (ATF) perfusion for influenza A virus production using suspension cellsVaccine, 32 (24), 2770–2781doi: 10.1016/j.vaccine.2014.02.016.

Reichl, U., Vazquez-Ramirez, D., Tapia, F., Nikolay, A., & Genzel, Y.Cell Culture-based Viral Vaccines: Process Intensification and MonitoringPresented at: Plenarsitzung der Sächischen Akademie der Wissenschaften zu LeipzigLeipzig, Germany, November 13, 2020.

Reichl, U., Vazquez-Ramirez, D., Tapia, F., Nikolay, A., Genzel, Y., & Rapp, E.Process Intensification in Viral Vaccine ManufacturingPresented at: International Symposium on Pharmaceutical Engineering Research – SPhEReBraunschweig, Germany, September 25, 2019.

Genzel, Y., Tapia, F., Vazquez-Ramirez, D., Jordan, I., Bürgin, T., Gangemi, D. J., & Reichl, U.Bioreactor options for continuous cell culture-derived viral vaccine production: less defective interfering particles through process intensificationPresented at: BioTech 2016: Biopharmaceutical Manufacturing and Single-Use TechnologiesWaedenswil, Switzerland, September 5, 2016.

Genzel, Y., Vazquez-Ramirez, D., Tapia, F., Jordan, I., & Reichl, U.Hollow Fiber-Based High-Cell-Density and Two-stage Bioreactor Continuous Cultivation: Options and limits Towards Process Intensification for Virus ProductionPresented at: Vaccine Technology VIAlbufeira, Portugal, June 12, 2016.

Pieler, M., Serve, A., Hennig, R., Vazquez-Ramirez, D., Wolff, M. W., & Reichl, U.Virus Particle Purification Using Magnetic Sulfated Cellulose ParticlesPresented at: Himmelfahrtstagung: New Frontiers for Biotech-Processes Rhein-Mosel-Halle Koblenz/Germany , May 2, 2016.

Reichl, U., Vazquez-Ramirez, D., Tapia, F., Jordan, I., Sandig, V., & Genzel, Y.Process options for high yield vaccine productionPresented at: Cell Culture Engineering XVPalms Springs, USA, May 8, 2016.

Vazquez-Ramirez, D., Nikolay, A., Behrendt, I., Jordan, I., Bürgin, T., Genzel, Y., & Reichl, U.High-cell-density cultivations by hollow fiber-based perfusion for intensified viral vaccine productionPresented at: VII SLATCC meeting Cocoyoc, Morelos, Mexico, November 3, 2016.

Vazquez-Ramirez, D., Lemke, V., Pieler, M., Genzel, Y., Jordan, I., Sandig, V., & Reichl, U.Process optimization for semi-continuous virus production at high cell densitiesPresented at: Cell Culture Engineering XVPalm Springs, CA, USA, May 8, 2016.

Vazquez-Ramirez, D., Nikolay, A., Genzel, Y., & Reichl, U.On-line monitoring tools in batch and (semi-)perfusion cultivations for vaccine productionPresented at: 4th BioProScale Symposium "Bioprocess intensification through Process Analytical Technology (PAT) and Quality by Design (QbD)"Berlin, April 6, 2016.

Genzel, Y., Tapia, F., Vogel, T., Vazquez-Ramirez, D., Behrendt, I., Jordan , I., Sandig, V., Hirschel, M., Gangemi, J. D., & Reichl, U.Disposable hollow fiber bioreactors for high cell density virus production in continuous modePresented at: Vaccine Technology 2014Playa del Carmen, Mexico, June 8, 2014.

Tapia, F., Vazquez-Ramirez, D., Lohr, V., Genzel, Y., Jordan, I., Sandig, V., & Reichl, U.A flow cytometry-based assay for quantification of infectious influenza and vaccinia virionsPresented at: Vaccine Technology 2014Playa del Carmen, Mexico, June 8, 2014.

Vazquez-Ramirez, D., Genzel, Y., Jordan, I., Sandig, V., & Reichl, U.Assessment of cultivation strategies for the production of Modified Vaccinia Ankara (MVA) at high cell-densitiesPresented at: Vaccine Technology 2014Playa del Carmen, Mexico, June 8, 2014.

Vazquez-Ramirez, D., Genzel, Y., Jordan, I., Sandig, V., & Reichl, U.Assessment of cultivation strategies for the production of Modified Vaccinia Ankara virus (MVA) at high cell-densitiesPresented at: ProcessNet-Jahrestagung und 31. DECHEMA-Jahrestagung der Biotechnologen 2014Aachen, Germany, September 30, 2014.

von Stosch, M., Vazquez-Ramirez, D., Lohr, V., de Azevedo, C., Luis, M., Genzel, Y., Reichl, U., & Oliveira, R.Towards effective media composition & process control optimization for high cell density cellbased virus productionPresented at: ESBES - 10th European Symposium on Biochemical Engineering SciencesLille, France, September 7, 2014.

Vazquez-Ramirez, D. (2021)Process intensification for the production of MVA and influenza A virus in high density suspension cultures of AGE1.CR.pIX cellsPhD Thesis, Otto-von-Guericke-Universität, Magdeburgdoi: 10.25673/55154.

Vazquez-Ramirez, D. (2012)Development of a flow cytometry-based assay for the quantification of active viral particlesMaster's Thesis, Technische Universität, Hamburg.