Publications of Y. Genzel

Genzel, Y., Ritter, J. B., König, S., Alt, R., & Reichl, U. (2005)Substitution of glutamine by pyruvate to reduce ammonia formation and growth inhibition of mammalian cellsBiotechnology Progress, 21 (1), 58–69doi: 10.1021/bp049827d.

Genzel, Y., Behrendt, I., König, S., Sann, H., & Reichl, U. (2004)Metabolism of MDCK Cells during cell growth and influenza virus production in large-scale microcarrier cultureVaccine, 22, 2202–2208doi: 10.1016/j.vaccine.2003.11.041.

Genzel, Y., König, S., & Reichl, U. (2004)Amino acid analysis in mammalian cell culture media containing serum and high glucose concentrations by anion exchange chromatography and integrated pulsed amperometric detectionAnalytical Biochemistry, 335, 119–125doi: 10.1016/j.ab.2004.08.020.

Genzel, Y. & Reichl, U. (2004)Bioprozesstechnik und Impfstoff-Forschung an der ElbeBioforum, 27 (5), 44–46.

Genzel, Y. & Reichl, U. (2002)Analysis of cell growth, virus replication and medium composition in equine influenza vaccine productionChemie-Ingenieur-Technik, 74 (5), 673–674doi: 10.1002/1522-2640(200205)74:5<673::AID-CITE673>3.0.CO;2-S.

Göbel, S., Pelz, L., Reichl, U., & Genzel, Y. (2023)Upstream processing for viral vaccines - Process intensificationBioprocessing of Viral Vaccines137–174.

Pelz, L., Göbel, S., Jaen , K., Reichl, U., & Genzel, Y. (2023)Upstream processing for viral vaccines – General aspectsBioprocessing of Viral Vaccines79–136.

Bürgin, T., Coronel, J., Hagens, G., Keebler, M. V., Genzel, Y., Reichl, U., & Anderlei, T. (2020)Orbitally Shaken Single-Use Bioreactor for Animal Cell Cultivation: Fed-Batch and Perfusion ModeAnimal Cell Biotechnology105–123New York: Humanadoi: 10.1007/978-1-0716-0191-4_7.

Nikolay, A., Bissinger, T., Gränicher, G., Wu, Y., Genzel, Y., & Reichl, U. (2020)Perfusion Control for High Cell Density Cultivation and Viral Vaccine ProductionAnimal Cell Biotechnology141–168New York: Humanadoi: 10.1007/978-1-0716-0191-4_9.

Genzel, Y., Rödig, J., Rapp, E., & Reichl, U. (2014)Vaccine production: Upstream processing with adherent or suspension cell linesAnimal Cell Biotechnology: Methods and Protocols371–393New York: HUMANA Press Inc.doi: 10.1007/978-1-62703-733-4_23.

Genzel, Y. & Reichl, U. (2007)Vaccine production - state of the art and future needs in upstream processingAnimal Cell Biotechnology: Methods and Protocols457–473Totowa, New Jersey: HUMANA Press Inc.doi: 10.1007/978-1-59745-399-8_21.

Ritter, J. B., Genzel, Y., & Reichl, U. (2007)Monitoring of Extracellular TCA Cycle Intermediates in Mammalian Cell CultureCell Technology for Cell Products: Proceedings of the 19th ESACT Meeting603–605Dordrecht, The Netherlands: Springerdoi: 10.1007/978-1-4020-5476-1_107.

Lohr, V., Rath, A., Jordan, I., Sandig, V., Genzel, Y., & Reichl, U. (2012)Avian Designer Cells AGE1.CR as Candidates for MVA and Influenza Vaccine ProductionIn: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), 615–631doi: 10.1007/978-94-007-0884-6_102.

Öncül, A. A., Genzel, Y., Reichl, U., & Thévenin, D. (2012)Flow characterization in wave bioreactors using Computational Fluid DynamicsIn: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), 455–469doi: 10.1007/978-94-007-0884-6_78.

Bock, A., Genzel, Y., & Reichl, U. (2010)Monitoring of Cell activity: online oxygen uptake rates in pulsed aerated cell cultureIn: Cells and Culture: Proceedings of the 20th ESACT Meeting, 391–396doi: 10.1007/978-90-481-3419-9_68.

Genzel, Y., Dietzsch, C., & Reichl, U. (2010)Comparing Vero and MDCK cells for influenza A virus production in microcarrier systemsIn: Cells and Culture: Proceedings of the 20th ESACT Meeting, 635–638doi: 10.1007/978-90-481-3419-9_109.

Öncül, A. A., Janiga, G., Genzel, Y., Reichl, U., & Thévenin, D. (2010)Two-population CFD simulation: microcarrier system for adherent cell growth in Wave BioreactorsIn: 4th International Conference on Population Balance Modelling: PBM 2010, 667–681.

Ritter, J. B., Genzel, Y., & Reichl, U. (2010)Metabolite Analysis in Mammalian Cells: How to generate reliable data sets?In: Cells and Culture: Proceedings of the 20th ESACT Meeting, 397–406doi: 10.1007/978-90-481-3419-9_69.

Schulze-Horsel, J., Schulze, M., Genzel, Y., & Reichl, U. (2010)Single-cell approach in influenza vaccine production: apoptosis and virus protein productionIn: Cells and Culture: Proceedings of the 20th ESACT Meeting, 25–28doi: 10.1007/978-90-481-3419-9_5.

Vester, D., Rapp, E., Genzel, Y., Gade, D., & Reichl, U. (2010)Proteomic analysis of influenza A virus infected mammalian cells by 2D-DIGEIn: Cells and Culture: Proceedings of the 20th ESACT Meeting, 429–432doi: 10.1007/978-90-481-3419-9_74.