Publications of Tilia Marlene Zinnecker

Journal Article (2)

2024
Journal Article
Zinnecker, T. M., Badri, N., Araujo, D., Thiele, K., Reichl, U., & Genzel, Y. (2024)From single‐cell cloning to high‐yield influenza virus production – implementing advanced technologies in vaccine process developmentEngineering in Life Sciences, 24 (4), 2300245doi: 10.1002/elsc.202300245.
Journal Article
Zinnecker, T. M., Reichl, U., & Genzel, Y. (2024)Innovations in cell culture-based influenza vaccine manufacturing – from static cultures to high cell density cultivationsHuman Vaccines & Immunotherapeutics, 20 (1), 2373521doi: 10.1080/21645515.2024.2373521.

Meeting Abstract (1)

2022
Meeting Abstract
Zinnecker, T. M., Behrendt, I., Lau, M., Hinkelmann, A., Thiele, K., Badri, N., Araujo, D., Genzel, Y., & Reichl, U. (2022)Automated single-cell cloning in chemically defined medium for new suspension MDCK cell lines and scale-down of influenza A virus production into ambr®15 microbioreactorsIn: Proceedings Vaccine Technology VIII, 55.

Talk (8)

2024
Talk
Genzel, Y., Zinnecker, T. M., Göbel, S., & Reichl, U.Next-generation virus production: from clone, to AMBR, to perfusion and very high virus yieldPresented at: 8th Edition of the "International Symposium on Immunobiologicals" (8th ISI)Rio de Janeiro (Brazil), May 7, 2024.
Talk
Zinnecker, T. M., Thiele, K., Schmidberger, T., Reichl, U., & Genzel, Y.Influenza A Virus Production following Quality by Design PrinciplesPresented at: Vaccine Technology IXLos Cabos (Mexico), May 19, 2024.
2023
Talk
Genzel, Y., Zinnecker, T. M., Göbel, S., & Reichl, U.Intensified cell-based virus production: A process development challenge for multiple cell-virus combinationsPresented at: 16th PEACe ConferenceSitges (Spain), September 24, 2023.
Talk
Genzel, Y., Zinnecker, T. M., Göbel, S., & Reichl, U.Next-Generation Virus Production: From Clone, to AMBR, to Perfusion and Very High Virus YieldPresented at: International Society for Vaccines (ISV) Annual CongressLausanne (Switzerland), October 22, 2023.
Talk
Genzel, Y., Zinnecker, T. M., Göbel, S., & Reichl, U.Increase in supply through use of new technologies for high yield vaccinesPresented at: Flanders VaccineBrussels (Belgium), November 12, 2023.
Talk
Zinnecker, T. M., Badri, N., Araujo, D., Hinkelmann, A., Thiele, K., Reichl, U., & Genzel, Y.Novel approach towards vaccine manufacturing: from single-cell cloning to high-yielding influenza virus productionPresented at: 4th Global Bioprocessing, Bioanalytics and ATMP Manufacturing CongressDublin (Ireland), May 15, 2023.
Talk
Zinnecker, T. M., Badri, N., Araujo, D., Hinkelmann, A., Thiele, K., Reichl, U., & Genzel, Y.A quest for the best influenza producing clonal MDCK cell line: intensifying by design of experiments, ambr15 and bench-top bioreactor cultivationsPresented at: World Biopharm Forum 2023 - Democratisation of biotherapies: new manufacturing modalities and intensificationsOxford (United Kingdom), June 21, 2023.
2022
Talk
Zinnecker, T. M., Behrendt, I., Lau , M., Hinkelmann, A., Thiele, K., Badri, N., Araujo, D., Genzel, Y., & Reichl, U.Automated single-cell cloning in chemically defined medium for new suspension MDCK cell lines and scale-down of influenza A virus production into ambr®15 microbioreactorsPresented at: Vaccine Technology VIIISitges (Spain), June 12, 2022.

Poster (5)

2024
Poster
Zinnecker, T. M., Thiele, K., Schmidberger, T., Reichl, U., & Genzel, Y.Influenza A Virus Production following Quality by Design PrinciplesPresented at: Vaccine Technology IXLos Cabos (Mexico), May 19, 2024.
Poster
Zinnecker, T. M., Thiele, K., Schmidberger, T., Reichl, U., & Genzel, Y.Implementation of Quality by Design Principles for Influenza A Virus ProductionPresented at: 28th ESACT MeetingEdingburgh (Scotland), June 23, 2024.
2022
Poster
Zinnecker, T. M., Badri, N., Araujo, D., Thiele, K., Genzel, Y., & Reichl, U.Generation and screening of monoclonal suspension MDCK cells for high-yield influenza A virus productionPresented at: 3rd ESACT Frontiers RetreatVienna, Austria, October 26, 2022.
Poster
Zinnecker, T. M., Behrendt, I., Lau , M., Hinkelmann, A., Thiele, K., Badri, N., Araujo, D., Genzel, Y., & Reichl, U.Automated single-cell cloning in chemically defined medium for new suspension MDCK cell lines and scale-down of influenza A virus production into ambr®15 microbioreactorsPresented at: Vaccine Technology VIIISitges (Spain), June 12, 2022.
Poster
Zinnecker, T. M., Behrendt, I., Lau, M., Hinkelmann, A., Thiele, K., Badri, N., Araujo, D., Genzel, Y., & Reichl, U.Suspension MDCK cell line development by automated single-cell cloning & scale-down into ambr®15 microbioreactors in chemically defined mediumPresented at: 27th ESACT MeetingLisbon (Portugal), June 26, 2022.

Thesis - Master (1)

2021
Thesis - Master
Zinnecker, T. M. (2021)Single-Cell Analysis of Influenza A Virus Defective Interfering Particle InfectionMaster's Thesis, Technische Universität, Berlin.
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