Publications of C. Seitz

Seitz, C., Isken, B., Heynisch, B., Rettkowski, M., Frensing, T., & Reichl, U. (2012)Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host responseApplied Microbiology and Biotechnology, 93 (2), 601–611doi: 10.1007/s00253-011-3569-8.

Frensing, T., Seitz, C., Heynisch, B., Patzina, C., Kochs, G., & Reichl, U. (2011)Efficient influenza B virus propagation due to deficient interferon-induced antiviral activity in MDCK cellsVaccine, 29 (41), 7125–7129doi: 10.1016/j.vaccine.2011.05.069.

Heynisch, B., Frensing, T., Heinze, K., Seitz, C., Genzel, Y., & Reichl, U. (2010)Differential activation of host cell signaling pathways through infection with two variants of influenza A /Puerto Rico /8/34 (H1N1) in MDCK cellsVaccine, 28 (51), 8210–8218doi: 10.1016/j.vaccine.2010.07.076.

Seitz, C., Frensing, T., Höper, D., Kochs, G., & Reichl, U. (2010)High yields of Influenza A virus in MDCK cells are promoted by an insufficient IFN-induced antiviral stateJournal of General Virology, 91 (7), 1754–1763doi: 10.1099/vir.0.020370-0.

Vester, D., Pflugmacher, A., Hoffmann, D., Seitz, C., Heldt, S., Bettenbrock, K., Genzel, Y., & Reichl, U. (2010)Real-time RT-qPCR assay for the analysis of human influenza A virus transcription and replication dynamicsJournal of Virological Methods, 168 (1-2), 63–71doi: 10.1016/j.jviromet.2010.04.017.

Heynisch, B., Frensing, T., Seitz, C., Genzel, Y., & Reichl, U.Analysis of the impact of innate immunity of MDCK cells on virus replication in influenza vaccine productionPresented at: ECAB 2011Berlin, September 26, 2011.

Frensing, T., Seitz, C., Heynisch, B., & Reichl, U.Influence of Host Cell Defence during Influenza Vaccine Production in MDCK CellsPresented at: Vaccine Technology IIIPuerto Vallarta, Mexiko, June 6, 2010.

Heynisch, B., Frensing, T., Seitz, C., & Reichl, U.Induction of innate immunity signaling pathways in MDCK cells and their relevance in a bioprocess for influenza vaccine productionPresented at: Molecular Interactions 2010Berlin, September 15, 2010.

Lagoda, A., Hoffmann, D., Vester, D., Seitz, C., Genzel, Y., & Reichl, U.Quantitative real time-PCR-assay for the analysis of gene-specific human influenza A virus transcription \& replication dynamicsPresented at: qPCR 2010Wien, Austria, April 7, 2010.

Seitz, C., Frensing, T., Heynisch, B., & Reichl, U.Einfluss der zelleigenen Pathogenabwehr auf die Influenza-Impfstoffproduktion in MDCK-ZellenPresented at: Dechema JahrestagungAachen, Germany, September 20, 2010.

Frensing, T., Seitz, C., Isken, B., Heynisch, B., Kochs, C., & Reichl, U.Influence of Host Cell Defence during Influenza Vaccine Production in Cell CulturePresented at: 22nd ESACT MeetingVienna, Austria, May 15, 2011.

Frensing, T., Seitz, C., Isken, B., Heynisch, B., Kochs, C., & Reichl, U.Influence of Host Cell Defence during Influenza Vaccine Production in Cell CulturePresented at: 22nd ESACT MeetingVienna, Austria, March 23, 2011.

Heynisch, B., Frensing, T., Seitz, C., Genzel, Y., & Reichl, U.Analysis of innate immunity signaling pathways in MDCK cells in an influenza virus vaccine production processPresented at: 22nd ESACT MeetingVienna, Austria, May 15, 2011.

Frensing, T., Seitz, C., Heynisch, B., Kochs, G., & Reichl, U.Influence of Host Cell Defence during Influenza Vaccine Production in MDCK CellsPresented at: Cell Symposia: InfluenzaWashington D.C., USA, December 2, 2010.

Frensing, T., Seitz, C., Heynisch, B., & Reichl, U.Influence of host cell defence during influenza vaccine production in cell culturePresented at: 4th European Congress of VirologyCernobbio, Como Lake, Italy, April 7, 2010.

Heynisch, B., Frensing, T., Seitz, C., Genzel, Y., & Reichl, U.Differential activation of host cell signaling pathways through infection with two variants of influenza A/PR/8/34 H1N1 in MDCK cellsPresented at: 4th European Congress of Virology / Annual Spring Meeting of GfV 2010Cernobbio, Lake Como, Italy, April 7, 2010.

Seitz, C., Frensing, T., & Reichl, U.IMPACT OF INTERFERON SIGNALLING ON VIRUS YIELD IN MAMMALIAN CELL CULTURE-BASED INFLUENZA VACCINE PRODUCTIONPresented at: 4th European Congress of VirologyCernobbio, Como Lake, Italy, April 7, 2010.

Heynisch, B., Seitz, C., Frensing, T., Genzel, G., & Reichl, U.Systems biology of influenza virus-host cell interaction in a bioprocess for vaccine productionPresented at: German Symposium on Systems Biology 2009Heidelberg, Germany, May 12, 2009.

Heynisch, B., Seitz, C., Frensing, T., Genzel, Y., & Reichl, U.Virus-host cell interactions in a bioprocess for influenza vaccine production - characterization of antiviral signaling pathwaysPresented at: ProcessNet-Jahrestagung 2009 und die 27.Jahrestagung der Biotechnologen Mannheim, Germany, September 8, 2009.

Heynisch, B., Seitz, C., Frensing, T., Genzel, Y., & Reichl, U.Analysis of antiviral signaling cascades in a bioprocess for influenza vaccine productionPresented at: 21st ESACT MeetingDublin, Ireland, June 7, 2009.