Publications of Hartmut Grammel

Journal Article (15)

2014
Journal Article
Carius, L., Rumschinski, P., Faulwasser, T., Flockerzi, D., Grammel, H., & Findeisen, R. (2014)Model-based derivation, analysis and control of unstable microaerobic steady-states-Considering Rhodospirillum rubrum as an exampleBiotechnology and Bioengineering, 111 (4), 734–747doi: 10.1002/bit.25140.
2013
Journal Article
Carius, L., Carius, A. B., McIntosh, M., & Grammel, H. (2013)Quorum sensing influences growth and photosynthetic membrane production in high-cell-density cultivations of Rhodospirillum rubrumBMC Microbiology, 13, 189doi: 10.1186/1471-2180-13-189.
Journal Article
Carius, L., Hädicke, O., & Grammel, H. (2013)Stepwise reduction of the culture redox potential allows the analysis of microaerobic metabolism and photosynthetic membrane synthesis in Rhodospirillum rubrumBiotechnology and Bioengineering, 110 (2), 573–585doi: 10.1002/bit.24734.
2012
Journal Article
Franz, A., Rehner, R., Kienle, A., & Grammel, H. (2012)Rapid selection of glucose-utilizing variants of the polyhydroxyalkanoate producer Ralstonia eutropha H16 by incubation with high substrate levelsLetters in Applied Microbiology, 54 (1), 45–51doi: 10.1111/j.1472-765X.2011.03171.x.
Journal Article
Rudolf, C. & Grammel, H. (2012)Fructose metabolism of the purple non-sulfur bacterium Rhodospirillum rubrum: Effect of carbon dioxide on growth, and production of bacteriochlorophyll and organic acidsEnzyme and Microbial Technology, 50 (4-5), 238–246doi: 10.1016/j.enzmictec.2012.01.007.
Journal Article
Wang, G.-S., Grammel, H., Abou-Aisha, K., Sägesser, R., & Gosh, R. (2012)High-Level Production of the Industrial Product Lycopene by the Photosynthetic Bacterium Rhodospirillum rubrumApplied and Environmental Microbiology, 78 (20), 7205–7215doi: 10.1128/AEM.00545-12.
2011
Journal Article
Carius, A. B., Henkel, M., & Grammel, H. (2011)Glutathione Redox Effect on Photosynthetic Membrane Expression in Rhodospirillum rubrumJournal of Bacteriology, 193 (8), 1893–1900doi: 10.1128/JB.01353-10.
Journal Article
Hädicke, O., Grammel, H., & Klamt, S. (2011)Metabolic network modeling of redox balancing and biohydrogen production in purple nonsulfur bacteriaBMC Systems Biology, 5, 150doi: 10.1186/1752-0509-5-150.
2010
Journal Article
Janke, R., Genzel, Y., Freund, S., Wolff, M. W., Grammel, H., Rühmkorf, C., Seidemann, J., Wahl, A., & Reichl, U. (2010)Expression, purification, and characterization of a His6-tagged glycerokinase from Pichia farinosa for enzymatic cycling assays in mammalian cellsJournal of Biotechnology, 150 (3), 396–403doi: 10.1016/j.jbiotec.2010.09.963.
Journal Article
Zeiger, L. & Grammel, H. (2010)Model-based high cell density cultivation of Rhodospirillum rubrum under respiratory dark conditionsBiotechnology and Bioengineering, 105 (4), 729–739doi: 10.1002/bit.22589.
2008
Journal Article
Antoniukas, L., Grammel, H., Sasnauskas, K., & Reichl, U. (2008)Profiling of external metabolites during production of hantavirus nucleocapsid protein with recombinant Saccharomyces cerevisiaeBiotechnology Letters, 30 (3), 415–420doi: 10.1007/s10529-007-9577-1.
Journal Article
Grammel, H. & Ghosh, R. (2008)Redox state dynamics of ubiquinone-10 imply cooperative regulation of photosynthetic membrane expression in Rhodospirillum rubrumJournal of Bacteriology, 190 (14), 4912–4921doi: 10.1128/JB.00423-08.
Journal Article
Klamt, S., Grammel, H., Straube, R., Ghosh, R., & Gilles, E. D. (2008)Modeling the electron transport chain of purple non-sulfur bacteriaMolecular Systems Biology, 4, 156doi: 10.1038/msb4100191.
2006
Journal Article
Antoniukas, L., Grammel, H., & Reichl, U. (2006)Production of hantavirus Puumala nucleocapsid protein in Saccharomyces cerevisiae for vaccine and diagnosticsJournal of Biotechnology, 124 (2), 347–362doi: 10.1016/j.jbiotec.2005.12.028.
2003
Journal Article
Grammel, H., Gilles, E. D., & Ghosh, R. (2003)Microaerophilic cooperation of reductive and oxidative pathways allows maximal photosynthetic membrane biosynthesis in Rhodospirillum rubrumApplied and Environmental Microbiology, 69 (11), 6577–6586doi: 10.1128/AEM.69.11.6577-6586.2003.

Talk (4)

2009
Talk
Grammel, H.High Cell Density Culture of Rhodospirillum rubrum and Photosynthetic Membrane Expression under Respiratory Dark ConditionsPresented at: 13th International Symposium on Phototrophic ProkaryotesMontreal, Canada, September 9, 2009.
Talk
Zeiger, L. & Grammel, H.Analysis and Design of Microaerophilic Processes by Combining Computational Models and In-Vivo SpectroscopyPresented at: 27. Dechema Jahrestagung der BiotechnologenMannheim, Germany, September 8, 2009.
2008
Talk
Grammel, H.Redox Phenomena in Photosynthetic Bacteria: Applications in Systems Biology and BiotechnologyPresented at: 1st FORSYS SymposiumBerlin, Germany, June 19, 2008.
Talk
Grammel, H.Redox Phenomena in Photosynthetic Bacteria: Applications in Systems Biology and BiotechnologyPresented at: Workshop “Dynamic Systems in Practice”Magdeburg, Germany, March 13, 2008.

Poster (5)

2011
Poster
Streif, S., Findeisen, R., Zeiger, L., Grammel, H., Janke, R., Genzel, Y., & Reichl, U.WPT7: Model Validation, Parameter Analysis and Experimental Design. Part I: Parameter estimation and model invalidation using uncertain data. Part II: Redox Signaling in the facultative photosynthetic bacterium Rhodospirillum rubrum. Part III: Sensitive cycling assays for measuring key metabolic enyzme activities in MDCK cells.Presented at: FORSYS/FORSYS Partner Status SeminarHeidelberg, Germany, February 15, 2011.
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