Publications of Steffen Klamt

Journal Article (117)

2025
Journal Article
Klamt, S., Zanghellini, J., & Kamp von, A. (2025)Minimal cut sets in metabolic networks: from conceptual foundations to applications in metabolic engineering and biomedicineBriefings in Bioinformatics, 26 (2), bbaf188doi: 10.1093/bib/bbaf188.
2024
Journal Article
Bauer, J. & Klamt, S. (2024)OptMSP: A Toolbox for Designing Optimal Multi-Stage (Bio)ProcessesJournal of Biotechnology, 383, 94–102doi: 10.1016/j.jbiotec.2024.01.009 .
Journal Article
Dietz, K., Sagstetter, C., Speck, M., Roth, A., Klamt, S., & Fabarius, J. T. (2024)A novel engineered strain of Methylorubrum extorquens for methylotrophic production of glycolic acidMicrobial Cell Factories, 23, 344doi: 10.1186/s12934-024-02583-y.
Journal Article
Espinel-Rios, S., Behrendt, G., Bauer, J., Morabito, B., Pohlodek, J., Schütze, A., Findeisen, R., Bettenbrock, K., & Klamt, S. (2024)Experimentally implemented dynamic optogenetic optimization of ATPase expression using knowledge-based and Gaussian-process-supported modelsProcess Biochemistry, (143), 174–185doi: 10.1016/j.procbio.2024.04.032.
Journal Article
Espinel-Rios, S., Morabito, B., Pohlodek, J., Bettenbrock, K., Klamt, S., & Findeisen, R. (2024)Toward a modeling, optimization, and predictive control framework for fed-batch metabolic cybergeneticsBiotechnology and Bioengineering, 121 (1), 366–379doi: 10.1002/bit.28575.
Journal Article
Frohwitter, J., Behrendt, G., Klamt, S., & Bettenbrock, K. (2024)A new Zymomonas mobilis platform strain for the efficient production of chemicalsMicrobial Cell Factories, 23, 143doi: 10.1186/s12934-024-02419-9 .
Journal Article
Huber, N., Alcalá Orozco, E. A., Rexer, T., Reichl, U., & Klamt, S. (2024)Model-based optimization of cell-free enzyme cascades exemplified for the production of GDP-fucoseMetabolic Engineering, 81, 10–25doi: 10.1016/j.ymben.2023.10.007.
Journal Article
Kutscha, R., Tomin, T., Birner-Gruenberger, R., Bekiaris, P. S., Klamt, S., & Pflügl, S. (2024)Efficiency of acetate-based isopropanol synthesis in Escherichia coli W is controlled by ATP demandBiotechnology for Biofuels and Bioproducts, 17, 110doi: 10.1186/s13068-024-02534-0 .
Journal Article
Schulz-Mirbach, H., Krüsemann, J. L., Andreadaki, T., Nerlich, J. N., Mavrothalassiti, E., Boecker, S., Schneider, P., Weresow, M., Abdelwahab, O., Paczia, N., Dronsella, B., Erb, T. J., Bar-Even, A., Klamt, S., & Lindner, S. N. (2024)Engineering new-to-nature biochemical conversions by combining fermentative metabolism with respiratory modulesNature Communications, 15 (1), 6725 doi: 10.1038/s41467-024-51029-x.
2023
Journal Article
Alcalá Orozco, E. A., Grote, V., Fiebig, T., Klamt, S., Reichl, U., & Rexer, T. (2023)A Cell‐Free Multi‐enzyme Cascade Reaction for the Synthesis of CDP‐GlycerolChemBioChem: A European Journal of Chemical Biology, 24 (21), e202300463doi: 10.1002/cbic.202300463.
Journal Article
Bekiaris, P. S. & Klamt, S. (2023)Network-wide thermodynamic constraints shape NAD(P)H cofactor specificity of biochemical reactionsNature Communications, 14, 4660doi: 10.1038/s41467-023-40297-8.
Journal Article
Boecker, S., Schulze, P., & Klamt, S. (2023)Growth-coupled anaerobic production of isobutanol from glucose in minimal medium with Escherichia coliBiotechnology for Biofuels and Bioproducts, 16, 148doi: 10.1186/s13068-023-02395-z .
Journal Article
Kamp von, A. & Klamt, S. (2023)Balancing biomass reaction stoichiometry and measured fluxes in flux balance analysisBioinformatics, 39 (10), btad600doi: 10.1093/bioinformatics/btad600.
Journal Article
Wichmann, J., Behrendt, G., Boecker, S., & Klamt, S. (2023)Characterizing and utilizing oxygen-dependent promoters for efficient dynamic metabolic engineeringMetabolic Engineering, 77, 199–207doi: 10.1016/j.ymben.2023.04.006 .
2022
Journal Article
Behrendt, G., Frohwitter, J., Vlachonikolou, M., Klamt, S., & Bettenbrock, K. (2022)Zymo-Parts: A Golden Gate Modular Cloning Toolbox for Heterologous Gene Expression in Zymomonas mobilisACS Synthetic Biology, 11 (11), 3855–3864doi: 10.1021/acssynbio.2c00428.
Journal Article
Boecker, S., Espinel-Rios, S., Bettenbrock, K., & Klamt, S. (2022)Enabling anaerobic growth of Escherichia coli on glycerol in defined minimal medium using acetate as redox sinkMetabolic Engineering, 73, 50–57doi: 10.1016/j.ymben.2022.05.006.
Journal Article
Espinel-Rios, S., Bettenbrock, K., Klamt, S., & Findeisen, R. (2022)Maximizing batch fermentation efficiency by constrained model-based optimization and predictive control of adenosine triphosphate turnoverAIChE-Journal, 68 (4), e17555doi: 10.1002/aic.17555.
Journal Article
Klamt, S. & Kamp von, A. (2022)Analyzing and Resolving Infeasibility in Flux Balance Analysis of Metabolic NetworksMetabolites, 12 (7), 585doi: 10.3390/metabo12070585.
Journal Article
Mahour, R., Lee, J. W., Grimpe, P., Boecker, S., Grote, V., Klamt, S., Seidel-Morgenstern, A., Rexer, T., & Reichl, U. (2022)Cell‐free multi‐enzyme synthesis and purification of uridine diphosphate galactoseChemBioChem, 23 (2), e202100361doi: 10.1002/cbic.202100361.
Journal Article
Schneider, P., Bekiaris, P. S., Kamp von, A., & Klamt, S. (2022)StrainDesign: a Comprehensive Python Package for Computational Design of Metabolic NetworksBioinformatics, 38 (21), 4981–4983doi: 10.1093/bioinformatics/btac632.
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