Publications of Sebastian Espinel-Rios

Journal Article (3)

2024
Journal Article
Espinel-Rios, S., Morabito, B., Pohlodek, J., Bettenbrock, K., Klamt, S., & Findeisen, R. (2024)Toward a modeling, optimization, and predictive control framework for fed-batch metabolic cybergeneticsBiotechnology and Bioengineering, 121 (1), 366–379doi: 10.1002/bit.28575.
2022
Journal Article
Boecker, S., Espinel-Rios, S., Bettenbrock, K., & Klamt, S. (2022)Enabling anaerobic growth of Escherichia coli on glycerol in defined minimal medium using acetate as redox sinkMetabolic Engineering, 73, 50–57doi: 10.1016/j.ymben.2022.05.006.
Journal Article
Espinel-Rios, S., Bettenbrock, K., Klamt, S., & Findeisen, R. (2022)Maximizing batch fermentation efficiency by constrained model-based optimization and predictive control of adenosine triphosphate turnoverAIChE-Journal, 68 (4), e17555doi: 10.1002/aic.17555.

Conference Paper (7)

2023
Conference Paper
Espinel-Rios, S., Bettenbrock, K., Klamt, S., Avalos, J. L., & Findeisen, R. (2023)Machine learning-supported cybergenetic modeling, optimization and control for synthetic microbial communitiesIn: 33rd European Symposium on Computer Aided Chemical Engineering, 2601–2606doi: 10.1016/B978-0-443-15274-0.50413-3.
Conference Paper
Espinel-Rios, S., Kok, R., Klamt, S., Avalos, J. L., & Findeisen, R. (2023)Batch-to-Batch Optimization with Model Adaptation Leveraging Gaussian Processes: The Case of Optogenetically Assisted Microbial ConsortiaIn: International Conference on Control, Automation and Systems, 1292–1297doi: 10.23919/ICCAS59377.2023.10316811.
Conference Paper
Espinel-Rios, S., Slaviero, G., Bettenbrock, K., Klamt, S., & Findeisen, R. (2023)Monitoring intracellular metabolite concentrations by moving horizon estimation based on kinetic modelingIn: IFAC-PapersOnLine, 4608–4613doi: 10.1016/j.ifacol.2023.10.968.
2022
Conference Paper
Espinel-Rios, S., Huber, N., Alcalá Orozco, E. A., Morabito, B., Rexer, T., Reichl, U., Klamt, S., & Findeisen, R. (2022)Cell-free biosynthesis meets dynamic optimization and control: a fed-batch frameworkIn: IFAC-PapersOnLine, 92–97doi: 10.1016/j.ifacol.2023.01.021.
Conference Paper
Espinel-Rios, S., Morabito , B., Pohlodek, J., Bettenbrock, K., Klamt, S., & Findeisen, R. (2022)Optimal control and dynamic modulation of the ATPase gene expression for enforced ATP wasting in batch fermentationsIn: IFAC-PapersOnLine, 174–180doi: 10.1016/j.ifacol.2022.07.440.
Conference Paper
Espinel-Rios, S., Morabito, B., Bettenbrock, K., & Findeisen, R. (2022)Soft sensor for monitoring dyamic changes in cell compositionIn: IFAC-PapersOnLine, 98–103doi: 10.1016/j.ifacol.2023.01.022.
Conference Paper
Morabito, B., Pohlodek, J., Kranert, L., Espinel-Rios, S., & Findeisen, R. (2022)Efficient and Simple Gaussian Process Supported Stochastic Model Predictive Control for Bioreactors using HILO-MPCIn: IFAC-PapersOnLine, 922–927doi: 10.1016/j.ifacol.2022.07.562.

Talk (3)

2023
Talk
Espinel-Rios, S., Bettenbrock, K., Klamt, S., Avalos, J. L., & Findeisen, R.Machine learning-supported cybergenetic modeling, optimization and control for synthetic microbial communitiesPresented at: 33rd European Symposium on Computer-Aided Process Engineering (ESCAPE-33)Athens, Greece, June 18, 2023.
Talk
Espinel-Rios, S., Slaviero, G., Bettenbrock, K., Klamt, S., & Findeisen, R.Monitoring intracellular metabolite concentrations by moving horizon estimation based on kinetic modelingPresented at: IFAC World Congress 2023Yokohama, Japan, July 9, 2023.
2022
Talk
Espinel-Rios, S., Morabito , B., Pohlodek, J., Bettenbrock, K., Klamt, S., & Findeisen, R.Optimal control and dynamic modulation of the ATPase gene expression for enforced ATP wasting in batch fermentationsPresented at: 13th IFAC Symposium on Dynamics and Control of Process Systems, including Biosystems, DYCOPS 2022Busan, Korea, June 14, 2022.
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