Publications of Oliver Hädicke

Witt, A., Pozzi, R., Diesch, S., Hädicke, O., & Grammel, H. (2019)New light on ancient enzymes – in vitro CO2 Fixation by Pyruvate Synthase of Desulfovibrio africanus and Sulfolobus acidocaldariusThe FEBS Journal, 286 (22), 4494–4508doi: 10.1111/febs.14981.

Hädicke, O., Kamp von, A., Aydogan, T., & Klamt, S. (2018)OptMDFpathway: Identification of metabolic pathways with maximal thermodynamic driving force and its application for analyzing the endogenous CO2 fixation potential of Escherichia coliPLoS Computational Biology, 14 (9), e1006492doi: 10.1371/journal.pcbi.1006492.

Klamt, S., Mahadevan, R., & Hädicke, O. (2018)When do two-stage processes outperform one-stage processes?Biotechnology Journal, 13 (2), 1700539doi: 10.1002/biot.201700539.

Hädicke, O. & Klamt, S. (2017)EColiCore2: a reference model of the central metabolism of Escherichia coli and the relationships to its genome-scale parent modelScientific Reports, 7, 39647 doi: 10.1038/srep39647.

Kamp von, A., Thiele, S., Hädicke, O., & Klamt, S. (2017)Use of CellNetAnalyzer in biotechnology and metabolic engineeringJournal of Biotechnology, 261, 221–228doi: 10.1016/j.jbiotec.2017.05.001.

Hädicke, O., Bettenbrock, K., & Klamt, S. (2015)Enforced ATP futile cycling increases specific productivity and yield of anaerobic lactate production in Escherichia coliBiotechnology and Bioengineering, 112 (10), 2195–2199doi: 10.1002/bit.25623.

Hädicke, O. & Klamt, S. (2015)Manipulation of the ATP pool as a tool for metabolic engineeringBiochemical Society Transactions (London), 43 (6), 1140–1145doi: 10.1042/BST20150141.

Lohr, V., Hädicke, O., Genzel, Y., Jordan, I., Buentemeyer, H., Klamt, S., & Reichl, U. (2014)The avian cell line AGE1.CR.pIX characterized by metabolic flux analysisBMC Biotechnology, 14, 72doi: 10.1186/1472-6750-14-72.

Carius, L., Hädicke, O., & Grammel, H. (2013)Stepwise reduction of the culture redox potential allows the analysis of microaerobic metabolism and photosynthetic membrane synthesis in Rhodospirillum rubrumBiotechnology and Bioengineering, 110 (2), 573–585doi: 10.1002/bit.24734.

Gruchattka, E., Hädicke, O., Klamt, S., Schuetz, V., & Kayser , O. (2013)In silico profiling of Escherichia coli and Saccharomyces cerevisiae as terpenoid factoriesMicrobial Cell Factories, 12, 84doi: 10.1186/1475-2859-12-84.

Hädicke, O., Lohr, V., Genzel, Y., Reichl, U., & Klamt, S. (2013)Evaluating differences of metabolic performances: Statistical methods and their application to animal cell cultivationsBiotechnology and Bioengineering, 110 (10), 2633–2642doi: 10.1002/bit.24926.

Hädicke, O., Grammel, H., & Klamt, S. (2011)Metabolic network modeling of redox balancing and biohydrogen production in purple nonsulfur bacteriaBMC Systems Biology, 5, 150doi: 10.1186/1752-0509-5-150.

Hädicke, O. & Klamt, S. (2011)Computing complex metabolic intervention strategies using constrained minimal cut setsMetabolic Engineering, 13 (2), 204–213doi: 10.1016/j.ymben.2010.12.004.

Hädicke, O. & Klamt, S. (2010)CASOP: a computational approach for strain optimization aiming at high productivityJournal of Biotechnology, 147 (2), 88–101doi: 10.1016/j.jbiotec.2010.03.006.

Klamt, S., Haedicke, O., & von Kamp, A. (2014)Stoichiometric and Constraint-Based Analysis of Biochemical Reaction NetworksLarge-Scale Networks in Engineering and Life Sciences263–316Cham: Springer International Publishingdoi: 10.1007/978-3-319-08437-4_5.

Hädicke, O., Pozzi, R., Witt, A., Oldiges, M., Klamt, S., & Grammel, H. (2016)Systembiologische Untersuchung bakterieller Stoffwechselnetzwerke und Enzyme für die technische Verwertung von COIn: Technische Systeme für die Lebenswissenschaften, 115–122.

Bohl, K., Figueiredo, L. F., Hädicke, O., Klamt, S., Kost, C., Schuster, S., & Kaleta, C. (2010)CASOP GS: Computing intervention strategies targeted at production improvement in genome-scale metabolic networksIn: German Conference on Bioinformatics 2010, 71–80.

Lohr, V., Haedicke, O., Genzel, Y., Jordan, I., Sandig, V., & Reichl, U.Comparative metabolic flux analyses of cultivations with novel avian designer cell lines used for vaccine productionPresented at: Cell Culture Engineering XIIIScottsdale, Arizona, USA, April 22, 2012.

Hädicke, O. (2014)Modellbasierte Identifizierung von Interventionsstrategien für StoffwechselnetzwerkePhD Thesis, Shaker Verlag, Aachen.