Publications of Sascha Young Kupke

Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Semi-Continuous propagation of Influenza A virus and its defective interfering particles: Analyzing the dynamic competition to select antiviral candidatesPresented at: 27th ESACT MeetingLisbon (Portugal), June 26, 2022.

Rüdiger, D., Küchler, J., Pontes, C., Kupke, S. Y., & Reichl, U.Modeling the intracellular replication of a new type of defective interfering particle of influenza virus with genomic nucleotide substitutionsPresented at: 12th European Conference on Mathematical and Theoretical BiologyHeidelberg (Germany), September 19, 2022.

Rüdiger, D., Pelz, L., Hein, M. D., Kupke, S. Y., & Reichl, U.Multiscale model of influenza A virus and defective interfering particle co-infection in animal cell culturePresented at: 5th Workshop on Virus Dynamicsvirtual, October 4, 2021.

Pelz, L., Rüdiger, D., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Evolution and selection of influenza a virus defective interfering particles in a semi-continuous production system for the use as antiviralPresented at: The seventh ESWI Influenza ConferenceVirtual Meeting, December 6, 2020.

Rüdiger, D., Pelz, L., Hein, M., Kupke, S. Y., & Reichl, U.Multiscale model of DIP replication and its effects on influenza A virus infection in animal cell culturePresented at: Society for Mathematical Biology 2020 Annual MeetingVirtual Meeting, August 17, 2020.

Kupke, S. Y., Riedel, D., Frensing, T., Zmora, P., & Reichl, U.A novel type of defective interfering particle for antiviral therapyPresented at: 26th ESACT MeetingCopenhagen, Denmark, May 5, 2019.

Rüdiger, D., Laske, T., Kupke, S. Y., & Reichl, U.Multiscale model of DIP interference and production during influenza A virus infection in animal cell culturePresented at: 4th Workshop on Virus DynamicsParis, France, October 21, 2019.

Kupke, S. Y.Single-Cell analysis uncover a novel influenza A virus-derived defective interfering particle for antiviral therapyPresented at: Vaccine Technology VIIMont Tremblant, Canada, June 17, 2018.

Rüdiger, D., Kupke, S. Y., Zmora, P., & Reichl, U.Multiscale model of influenza virus infection predicts viral release dynamics in cell cultures for a wide range of infection conditionsPresented at: 3rd Workshop on Virus DynamicsHeidelberg, Germany, October 6, 2017.

Kupke, S. Y., Heldt, S., Frensing, T., & Reichl, U.Single-Cell Analysis of Influenza A Virus-Infected CellsPresented at: 26th Annual Meeting of the Society for VirologyMünster, Germany, July 7, 2016.

Kupke, S. Y., Heldt, S., Frensing, T., & Reichl, U.Heterogeneity in Influenza A Virus Infection Unveiled by Single-Cell Analysis and Stochastic Mathemeatical ModelingPresented at: Single Cell Technologies 2016Frankfurt/Main, April 6, 2016.

Kupke, S. Y., Heldt, S., Frensing, T., & Reichl, U.Single-Cell Analysis of Influenza A Virus-Infected Cells for the Optimization of Cell Culture-Based Vaccine ProductionPresented at: Vaccine Technology VIAlbufeira, Portugal, June 12, 2016.

Dogra, T., Pelz, L., Rüdiger, D., Hein, M., Baelkner, M., Boehme, J. D., Marichal-Gallardo, P., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U.Genetically engineered defective interfering particles of influenza A virus for antiviral treatment and vaccinationPresented at: 9^th European Congress of Virology (ECV)Cavtat/Dubrovnik (Croatia), April 27, 2025.

Piasecka, J., Kupke, S. Y., & Reichl, U.Genetically engineered influenza defective interfering particles with enhanced immune activation potential and antiviral efficacy in vitroPresented at: 9^th European Congress of Virology (ECV)Cavtat/Dubrovnik (Croatia), April 27, 2025.

Piasecka, J., Rüdiger, D., Küchler, J., Kupke, S. Y., & Reichl, U.Molecular basis for the antiviral activity of the influenza defective interfering particle “OP7”Presented at: 34^th Annual Meeting of the Society for VirologyHamburg (Germany), March 4, 2025.

Rüdiger, D., Piasecka, J., Küchler, J., Kupke, S. Y., & Reichl, U.The secrets of “OP7”, an influenza DIP: mathematical model, impact of mutations and antiviral mechanismsPresented at: 34^th Annual Meeting of the Society for VirologyHamburg (Germany), March 4, 2025.

Rüdiger, D., Piasecka, J., Küchler, J., Kupke, S. Y., & Reichl, U.The secrets of “OP7”, an influenza DIP: mathematical model, impact of mutations and antiviral mechanismsPresented at: 9^th European Congress of Virology (ECV)Cavtat/Dubrovnik (Croatia), April 27, 2025.

Dogra, T., Pelz, L., Rüdiger, D., Hein, M. D., Böhme, J., Bälkner, M., Kershaw, O., Marichal-Gallardo, P., Gruber, A., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U.Genetically engineered defective interfering particles for antiviral treatment and vaccinationPresented at: 28th ESACT MeetingEdingburgh (Scotland), June 23, 2024.

Pelz, L., Dogra, T., Rüdiger, D., Boehme, J., Kershaw, O., Bruder, D., Kupke, S. Y., & Reichl, U.Defective Interfering Particles of Influenza A Virus As Broad-Spectrum AntiviralsPresented at: 33^rd Annual Meeting of the Society for Virology (GfV)Vienna (Austria), March 25, 2023.

Piasecka, J., Rüdiger, D., Küchler, J., Kupke, S. Y., & Reichl, U.Mechanisms of antiviral action of the influenza defective interfering particle “OP7”Presented at: 33^rd Annual Meeting of the Society for Virology (GfV)Vienna (Austria), March 25, 2023.