Publications of Sascha Young Kupke

Kupke, S. Y., Riedel, D., Frensing, T., Zmora, P., & Reichl, U.A novel type of defective interfering particle for antiviral therapyPresented at: 26th ESACT MeetingCopenhagen, Denmark, May 5, 2019.

Rüdiger, D., Laske, T., Kupke, S. Y., & Reichl, U.Multiscale model of DIP interference and production during influenza A virus infection in animal cell culturePresented at: 4th Workshop on Virus DynamicsParis, France, October 21, 2019.

Kupke, S. Y.Single-Cell analysis uncover a novel influenza A virus-derived defective interfering particle for antiviral therapyPresented at: Vaccine Technology VIIMont Tremblant, Canada, June 17, 2018.

Rüdiger, D., Kupke, S. Y., Zmora, P., & Reichl, U.Multiscale model of influenza virus infection predicts viral release dynamics in cell cultures for a wide range of infection conditionsPresented at: 3rd Workshop on Virus DynamicsHeidelberg, Germany, October 6, 2017.

Kupke, S. Y., Heldt, S., Frensing, T., & Reichl, U.Single-Cell Analysis of Influenza A Virus-Infected CellsPresented at: 26th Annual Meeting of the Society for VirologyMünster, Germany, July 7, 2016.

Kupke, S. Y., Heldt, S., Frensing, T., & Reichl, U.Heterogeneity in Influenza A Virus Infection Unveiled by Single-Cell Analysis and Stochastic Mathemeatical ModelingPresented at: Single Cell Technologies 2016Frankfurt/Main, April 6, 2016.

Kupke, S. Y., Heldt, S., Frensing, T., & Reichl, U.Single-Cell Analysis of Influenza A Virus-Infected Cells for the Optimization of Cell Culture-Based Vaccine ProductionPresented at: Vaccine Technology VIAlbufeira, Portugal, June 12, 2016.

Pelz, L., Dogra, T., Rüdiger, D., Boehme, J., Kershaw, O., Bruder, D., Kupke, S. Y., & Reichl, U.Defective Interfering Particles of Influenza A Virus As Broad-Spectrum AntiviralsPresented at: 33^rd Annual Meeting of the Society for Virology (GfV)Vienna (Austria), March 25, 2023.

Piasecka, J., Rüdiger, D., Küchler, J., Kupke, S. Y., & Reichl, U.Mechanisms of antiviral action of the influenza defective interfering particle “OP7”Presented at: 33^rd Annual Meeting of the Society for Virology (GfV)Vienna (Austria), March 25, 2023.

Dogra, T., Pelz, L., Rüdiger, D., Hein, M. D., Baelkner, M., Julia D. Boehme, J. D., Marichal-Gallardo, P., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U.Genetically engineered defective interfering particles of influenza A virus for antiviral treatment and vaccinationPresented at: 32^nd Annual Meeting of the Society for Virology (GfV)Ulm (Germany), March 28, 2023.

Dogra, T., Pelz, L., Rüdiger, D., Hein, M. D., Baelkner, M., Julia D. Boehme, J. D., Marichal-Gallardo, P., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U.Genetically engineered defective interfering particles of influenza A virus for antiviral treatment and vaccinationPresented at: 8^th European Congress of VirologyGdańsk (Poland), May 4, 2023.

Küchler, J., Opitz, P., Kupke, S. Y., Genzel, Y., Benndorf, D., & Reichl, U.Absolute quantification of viral proteins during single-round replication of vaccine producer cell linesPresented at: 32^nd Annual Meeting of the Society for Virology (GfV) Ulm (Germany), March 28, 2023.

Küchler, J., Opitz, P., Kupke, S. Y., Genzel, Y., Benndorf, D., & Reichl, U.Absolute quantification of influenza A virus proteins during single-round replication in vaccine producer cell linesPresented at: 16^th PEACe (Protein Expression in Animal Cells) ConferenceSitges (Spain), September 24, 2023.

Pelz, L., Dogra, T., Boehme, J. D., Hein, M. D., Marichal-Gallardo, P., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U.Influenza A virus OP7 defective interfering particles: Cell culture-based production and antiviral efficacy in vivoPresented at: Cell Culture Engineering (CCE) XVIII Cancun (Mexico), April 23, 2023.

Pelz, L., Dogra, T., Boehme, J. D., Marichal-Gallardo, P., Hein, M. D., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U.A Scalable High-Yield Process for Production of Influenza A Virus Defective Interfering Particles and In Vivo StudiesPresented at: Himmelfahrtstagung on Bioprocess Engineering 2023Weimar (Germany), May 15, 2023.

Pelz, L., Dogra, T., Boehme, J. D., Marichal-Gallardo, P., Hein, M. D., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U.Influenza A Virus Chimeric OP7 Defective Interfering Particles: Cell Culture-based Production and In Vivo Antiviral EfficacyPresented at: 32^nd Annual Meeting of the Society for Virology (GFV)Ulm (Germany), March 25, 2023.

Piasecka, J., Rüdiger, D., Kupke, S. Y., & Reichl, U.Reduced transcription of the mutated genomic segment 7 of the novel “OP7” influenza defective interfering particle intended for use as an antiviralPresented at: 8^th European Congress of VirologyGdańsk (Poland), May 4, 2023.

Piasecka, J., Rüdiger, D., Kupke, S. Y., & Reichl, U.Promoter mutations in novel “OP7” influenza defective interfering particle severely reduce transcription of its genomic segment 7Presented at: 32^nd Annual Meeting of the Society for Virology (GfV)Ulm (Germany), March 28, 2023.

Piasecka, J., Rüdiger, D., Kupke, S. Y., & Reichl, U.Promoter mutations in the novel “OP7” influenza defective interfering particle intended for use as antiviralPresented at: 17^th Vaccine CongressGlasgow (Scotland), September 24, 2023.

Dogra, T., Pelz, L., Marc, H., Rüdiger, D., Boehme, J., Bruder, D., Kupke, S. Y., & Reichl, U.Reverse genetics for Influenza A virus to generate genetically engineered defective interfering particles for antiviral treatment and vaccinationPresented at: 27th ESACT MeetingLisbon (Portugal), June 26, 2022.