Head of the Group

Prof. Dr.-Ing. Udo Reichl
Prof. Dr.-Ing. Udo Reichl
Phone: +49 391 6110 201
Fax: +49 391 6110 203
Room: N0.19

Contact Person

Annegret Frauendienst
Phone:+49 391 6110-200Fax:+49 391 6110-203

Group Page

Publications

Publications BPE group

Journal Article (18)

  1. Journal Article
    Bdeir, N.; Arora, P.; Gärtner, S.; Hoffmann, M.; Reichl, U.; Pöhlmann, S.; Winkler, M.: A system for production of defective interfering particles in the absence of infectious influenza A virus. PLoS One 14 (3), e0212757 (2019)
  2. Journal Article
    Bissinger, T.; Fritsch, J.; Mihut, A. N.; Wu, Y.; Liu, X.; Genzel, Y.; Tan, W.-S.; Reichl, U.: Semi-perfusion cultures of suspension MDCK cells enable high cell concentrations and efficient influenza A virus production. Vaccine (accepted)
  3. Journal Article
    Campbell, M.P.; Abrahams, J.L.; Rapp, E.; Struwe, W.B.; Costello, C.E.; Novotny, M.; Ranzinger, R.; York, W.S.; Kolarich, D.; Rudd, P.M. et al.; Kettner, C.: The minimum information required for a glycomics experiment (MIRAGE) project: LC guidelines. Glycobiology 29 (5), pp. 349 - 354 (2019)
  4. Journal Article
    Coronel, J.; Behrendt, I.; Bürgin, T.; Anderlei, T.; Sandig, V.; Reichl, U.; Genzel, Y.: Influenza A virus production in a single-use orbital shaken bioreactor with ATF or TFF perfusion systems. Vaccine (accepted)
  5. Journal Article
    Fischöder, T.; Cajic, S.; Reichl, U.; Rapp, E.; Elling , L.: Enzymatic cascade synthesis provides novel linear human milk oligosaccharides as reference standards for xCGE-LIF based high-throughput analysis. Biotechnology Journal 14 (3), 1800305 (2019)
  6. Journal Article
    Fortuna, A. R.; Van Teeffelen, S.; Ley, A.; Fischer, L. M.; Taft, F.; Genzel, Y.; Villain, L.; Wolff, M.; Reichl, U.: Use of sulfated cellulose membrane adsorbers for chromatographic purification of cell cultured-derived influenza A and B viruses. Separation and Purification Technology (226), pp. 350 - 358 (2019)
  7. Journal Article
    Gränicher, G.; Coronel, J.; Pralow, A.; Marichal-Gallardo, P.; Wolff, M. W.; Rapp, E.; Karlas, A.; Sandig, V.; Genzel, Y.; Reichl, U.: Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG.PK2.1. Vaccine (accepted)
  8. Journal Article
    Koch, S.; Kohrs, F.; Lahmann, P.; Bissinger, T.; Wendschuh, S.; Benndorf, D.; Reichl, U.; Klamt, S.: RedCom: A strategy for reduced metabolic modeling of complex microbial communities and its application for analyzing experimental datasets from anaerobic digestion. PLoS Computational Biology 15 (2), e1006759 (2019)
  9. Journal Article
    Kupke, S. Y.; Riedel, D.; Frensing, T.; Zmora, P.; Reichl, U.: A Novel Type of Influenza A Virus-Derived Defective Interfering Particle with Nucleotide Substitutions in Its Genome. Journal of Virology 93 (4), 01786-18 (2019)
  10. Journal Article
    Munoz, R.I.; Kaehne, T.; Herrera, H.; Rodriguez, S.; Guerra, M.M.; Vio , K.; Hennig, R.; Rapp, E.; Rodriguez, E.: The subcommissural organ and the Reissner fiber: old friends revisited. Cell and Tissue Research 375 (2), pp. 507 - 529 (2019)
  11. Journal Article
    Reiding, K.R.; Bondt, A.; Hennig, R.; Gardner, R.A.; O'Flaherty, R.; Trbojević-Akmačić, I.; Shubhakar, A.; Hazes, J.; Reichl, U.; Fernandes, D.L. et al.; Pucic-Bakovic, M.; Rapp, E.; Spencer, D.I.R.; Dolhain, R.; Rudd, P.; Lauc, G.; Wuhrer, M.: High-throughput serum N-glycomics: method comparison and application to study rheumatoid arthritis and pregnancy-associated changes. Molecular and Cellular Proteomics 18 (1), pp. 3 - 15 (2019)
  12. Journal Article
    Rossdam, C.; Konze, S.; Oberbeck, A.; Rapp, E.; Gerardy-Schahn, R.; von Itzstein, M.; Buettner, F.: Approach for Profiling of Glycosphingolipid Glycosylation by Multiplexed Capillary Gel Electrophoresis Coupled to Laser-Induced Fluorescence Detection to Identify Cell-Surface Markers of Human Pluripotent Stem Cells and Derived Cardiomyocytes. Analytical Chemistry 91 (10), pp. 6413 - 6418 (2019)
  13. Journal Article
    Rüdiger, D.; Kupke, S. Y.; Laske, T.; Zmora, P.; Reichl, U.: Multiscale modeling of influenza A virus replication in cell cultures predicts infection dynamics for highly different infection conditions. PLoS Computational Biology 15 (2), e1006819 (2019)
  14. Journal Article
    Scoma, A.; Heyer, R.; Rifai, R.; Dandyk, C.; Marshall, I.; Kerckhof, F.-M.; Marietou, A.; Boshker, H. T. S.; Meysman, F. J. R.; Malmos, K. G. et al.; Vosegaard, T.; Vermeir, P.; Banat, I. M.; Benndorf, D.; Boon, N.: Reduced TCA cycle rates at high hydrostatic pressure hinder hydrocarbon degradation and obligate oil degraders in natural, deep-sea microbial communities. The ISME Journal 13 (4), pp. 1004 - 1018 (2019)
  15. Journal Article
    Thorn, C.E.; Bergesch , C.; Joyce, A.; Sambrano, G.; McDonnell, K.; Brennan, F.; Heyer, R.; Benndorf, D.; Abram, F.: A robust, cost-effective method for DNA, RNA and protein co-extraction from soil, other complex microbiomes, and pure cultures. Molecular Ecology Resources 19 (2), pp. 439 - 455 (2019)
  16. Journal Article
    Vazquez-Ramirez, D.; Jordan, I.; Sandig, V.; Genzel, Y.; Reichl, U.: High titer MVA and influenza A virus production using a hybrid fed-batch/perfusion strategy with an ATF system. Applied Microbiology and Biotechnology 103 (7), pp. 3025 - 3035 (2019)
  17. Journal Article
    Weigel, T.; Soliman, R.; Wolff, M.; Reichl, U.: Hydrophobic-interaction chromatography for purification of influenza A and B virus. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences 1117, pp. 103 - 117 (2019)
  18. Journal Article
    Weinrich, S.; Koch, S.; Bonk, F.; Popp, D.; Benndorf, D.; Klamt, S.; Centler, F.: Augmenting Biogas Process Modeling by Resolving Intracellular Metabolic Activity. Frontiers in Microbiology 10, 1095 (2019)

Meeting Abstract (2)

  1. Meeting Abstract
    Marichal-Gallardo, P.; Genzel, Y.; Börner, K.; Grimm, D.; Wolff, M. W.; Reichl, U.: A single-use chromatographic purification platform for viral gene transfer vectors & viral vaccines. In Advancing Manufacture of Cell and Gene Therapies VI: Proceedings, 92. Advancing Manufacture of Cell and Gene Therapies VI, Coronado, California, January 27, 2019 - January 31, 2019. (2019)
  2. Meeting Abstract
    Marichal-Gallardo, P.; Genzel, Y.; Börner, K.; Grimm, D.; Wolff, M. W.; Reichl, U.: A single-use chromatographic purification platform for viral gene transfer vectors & viral vaccines. In Proceedings Advancing Manufacture of Cell and Gene Therapies VI. Advancing Manufacture of Cell and Gene Therapies VI, Loews Coronado Bay Hotel Coronado, California, USA, January 27, 2019 - January 31, 2019. (2019)

Talk (4)

  1. Talk
    Hinneburg, H.; Schirmeister, F.; Nguyen-Khuong, T.; Packer, N.H.; Rapp, E.; Thayseb-Andersen, M.: Post-Column Make-up Flow (PCMF) Enhances the Sensitivity of Capillary-Flow PCG-LC-MS/Based Glycomics. GlycoBioTec 2019, Berlin, Germany (2019)
  2. Talk
    Mahour, R.; Marichal-Gallardo, P.; Cvijetinovic, S.; Babakhani, M.; Rexer, T.; Reichl, U.: A multi-enzyme process for production of glycosyltransferase substrates: activated sugars. GlycoBioTec 2019, Berlin, Germany (2019)
  3. Talk
    Rapp, E.; Hennig, R.; Cajic, S.; Behne , A.; Muth, T.; Kottler, R.; Reichl, U.: glyXbox CE: A powerful tool in the glycoanalytical toolbox - improving biologics development. GlycoBioTec 2019, Berlin, Germany (2019)
  4. Talk
    Rossdamm, C.; Konze , S.A.; Oberbeck, A.; Rapp, E.; Gerardy-Schahn, R.; von Itzstein, M.; Buettner, F.F.R.: xCGE-LIF as a novel approach for the analysis of glycoshingolipid-derived glycans. GlycoBioTec 2019, Berlin, Germany (2019)

Poster (7)

  1. Poster
    Chuzel, L.; Ganatra, M.B.; Fossa, S.L.; Rapp, E.; Taron, C.: A functional metagenomics workflow for discovery of novel glycoside hydrolases. GlycoBioTec 2019, Berlin, Germany (2019)
  2. Poster
    Grote, V.; Cornean, A.; Hoffmann, M.; Thumberger, T.; Wittbrodt, J.; Reichl, U.; Rapp, E.: Embryonic Development in CDG Model Organism: Site-specific Glycoproteomic Analysis of O-Mannosylation in Oryzias Latipes. GlycoBioTec 2019, Berlin, Germany (2019)
  3. Poster
    Hanic, M.; McLeod, B.; Shi, S.; Rapp, E.; Hennig, R.; Lauc, G.; Trbojevic-Akmacic, I.: N-glycans sequencing using a novel exoglycosidase arry and xCGE-LIF analysis. GlycoBioTec 2019, Berlin, Germany (2019)
  4. Poster
    Hoffmann, M.; Pioch, M.; Pralow, A.; Hennig, R.; Kottler, R.; Reichl, U.; Rapp, E.: The Fine Art of Destruction: A Guide to In-Depth Glycoproteomic Analyses - Exploiting the Diagnostic Potential of Fragment Ions. GlycoBioTec 2019, Berlin, Germany (2019)
  5. Poster
    Pralow, A.; Hoffmann, M.; Pioch, M.; Hennig, R.; Nguyen-Khuong, T.; Genzel, Y.; Rapp, E.; Reichl, U.: Comprehensive N-glycosylation analysis of influenza A virus antigens derived from different production cell lines reveal immunogenic glycan epitopes. GlycoBioTec 2019, Berlin, Germany (2019)
  6. Poster
    Rossdamm, C.; Konze , S.A.; Oberbeck, A.; Rapp, E.; Gerardy-Schahn, R.; von Itzstein, M.; Buettner, F.F.R.: xCGE-LIF as a novel approach for the analysis of glycoshingolipid-derived glycans. GlycoBioTec 2019, Berlin, Germany (2019)
  7. Poster
    Zuniga-Banuelos, F.; Hoffmann, M.; Reichl, U.; Rapp, E.: In-Depth N-Glycoproteomic Analysis of Human Blood Plasma Proteins. GlycoBioTec 2019, Berlin, Germany (2019)

Patent (2)

  1. Patent
    Tapia, F.; Genzel, Y.; Reichl, U.: Plug Flow Tubular Bioreactor , System Containing the same and Method for Production of Virus. US 20190119616 (2019)
  2. Patent
    Wolff, M. W.; Pieler, M.; Reichl, U.; Marichal-Gallardo, P.: Method for the Separation of Virus Compositions Including Depletion and Purification thereof. US 20190085300 (2019)
 
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