Publications

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Journal Article (5)

  1. 1.
    Journal Article
    Rey-Jurado, E.; Tapia, F.; Muñoz-Durango, N.; Lay, M.K.; Carreño, L. J.; Riedel, C. A.; Bueno, S. M.; Genzel, Y.; Kalergis, A. M.: Assessing the Importance of Domestic Vaccine Manufacturing Centers: An Overview of Immunization Programs, Vaccine Manufacture, and Distribution. Frontiers in immunology 9, 26 (2018)
  2. 2.
    Journal Article
    Tapia, F.; Jordan, I.; Genzel, Y.; Reichl, U.: Efficient and stable production of Modified Vaccinia Ankara virus in two-stage semi-continuous and in continuous stirred tank cultivation systems. PLoS One 12 (8), e0182553 (2017)
  3. 3.
    Journal Article
    Tapia, F.; Vázquez-Ramirez, D.; Genzel, Y.; Reichl, U.: Bioreactors for high cell density and continuous multi-stage cultivations: options for process intensification in cell culture-based viral vaccine production. Applied Microbiology and Biotechnology 100 (5), pp. 2121 - 2132 (2016)
  4. 4.
    Journal Article
    Diba, M.; Goudouri, O.-M.; Tapia, F.; Boccaccini, A. R.: Magnesium-containing bioactive polycrystalline silicate-based ceramics and glass-ceramics for biomedical applications. Current Opinion in solid state & materials science 18 (3), pp. 147 - 167 (2014)
  5. 5.
    Journal Article
    Tapia, F.; Vogel, T.; Genzel, Y.; Behrendt, I.; Hirschel, M.; Gangemi, J. D.; Reichl, U.: Production of high-titer human influenza A virus with adherent and suspension MDCK cells cultured in a single-use hollow fiber bioreactor. Vaccine 32 (8), pp. 1003 - 1011 (2014)

Meeting Abstract (1)

  1. 6.
    Meeting Abstract
    Tapia, F.; Genzel, Y.; Reichl, U.; Sandig, V.: Stirred tanks in cascades and plug-flow tubular bioreactors for continuous production of viral vaccines. In: ECI Symposium Series. Integrated Continuous Biomanufacturing III, Cascais, Portugal, September 17, 2017 - September 21, 2017. (2017)

Talk (7)

  1. 7.
    Talk
    Tapia, F.: A continuous tubular bioreactor for stable production of influenza virus vaccines. 25th ESACT Meeting, Lausanne, Switzerland (2017)
  2. 8.
    Talk
    Tapia, F.: A continuous tubular bioreactor for stable production of influenza virus vaccines. CChIQ2017: National Conference of Chemical Engineering, Santiago, Chile (2017)
  3. 9.
    Talk
    Tapia, F.: A continuous tubular bioreactor for stable production of influenza virus vaccines. SOMICH Coloquios de Microbiologia, Santiago, Chile (2017)
  4. 10.
    Talk
    Genzel, Y.; Vazquez-Ramirez, D.; Tapia, F.; Jordan, I.; Reichl, U.: Hollow Fiber-Based High-Cell-Density and Two-stage Bioreactor Continuous Cultivation: Options and limits Towards Process Intensification for Virus Production. Vaccine Technology VI, Albufeira, Portugal (2016)
  5. 11.
    Talk
    Genzel, Y.; Tapia, F.; Vazquez-Ramirez, D.; Jordan, I.; Bürgin, T.; Gangemi, D. J.; Reichl, U.: Bioreactor options for continuous cell culture-derived viral vaccine production: less defective interfering particles through process intensification. BioTech 2016: Biopharmaceutical Manufacturing and Single-Use Technologies, Waedenswil, Switzerland (2016)
  6. 12.
    Talk
    Reichl, U.; Vazquez-Ramirez, D.; Tapia, F.; Jordan, I.; Sandig, V.; Genzel, Y.: Process options for high yield vaccine production. Cell Culture Engineering XV, Palms Springs, USA (2016)
  7. 13.
    Talk
    Tapia, F.: Plug flow tubular and stirred tanks bioreactors for continuous vaccine production. Continuous Biomanufacturing Conference, Oxford, United Kingdom (2016)

Poster (8)

  1. 14.
    Poster
    Tapia, F.; Genzel, Y.; Jordan, I.; Sandig, V.; Reichl, U.: Options for continuous virus vaccines production: options for continuous virus vaccines production: tubular plug-flow bioreactor vs. cascades of CSTRs. Integrated Continuous Biomanufacturing III, Cascais, Portugal (2017)
  2. 15.
    Poster
    Tapia, F.; Genzel, Y.; Jordan, I.; Sandig, V.; Reichl, U.: Towards integrated continuous viral vaccines production using two-stage bioreactor systems. Cell Culutre Engineering Conference XV, Palms Springs, USA (2016)
  3. 16.
    Poster
    Tapia, F.; Genzel, Y.; Jordan, I.; Sandig, V.; Reichl, U.: Propagation of influenza and MVA virus in cascades of continuous stirred tank bioreactors: challenging the "von Magnus effect". Vaccine Technology VI, Albufeira, Portugal (2016)
  4. 17.
    Poster
    Tapia, F.; Genzel, Y.; Jordan, I.; Sandig, V.; Reichl, U.: Continuous production of viral vaccines with a two-stage bioreactor system. Conference Integrated Continuous Biomanufacturing II, Berkeley, California, USA (2015)
  5. 18.
    Poster
    Tapia, F.; Genzel, Y.; Jordan, I.; Sandig, V.; Reichl, U.: Continuous and semi-continuous production of MVA-virus in two-stage bioreactor systems. 24th Meeting of the European Society for Animal Cell Technology, ESACT 2015, Barcelona, Spain (2015)
  6. 19.
    Poster
    Genzel, Y.; Tapia, F.; Vogel, T.; Vazquez-Ramirez, D.; Behrendt, I.; Jordan , I.; Sandig, V.; Hirschel, M.; Gangemi, J.D.; Reichl, U.: Disposable hollow fiber bioreactors for high cell density virus production in continuous mode. Vaccine Technology 2014, Playa del Carmen, Mexico (2014)
  7. 20.
    Poster
    Tapia, F.; Vazquez-Ramirez, D.; Lohr, V.; Genzel, Y.; Jordan, I.; Sandig, V.; Reichl, U.: A flow cytometry-based assay for quantification of infectious influenza and vaccinia virions. Vaccine Technology 2014, Playa del Carmen, Mexico (2014)
 
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