Head of the Group

Prof. Dr.-Ing. Udo Reichl
Prof. Dr.-Ing. Udo Reichl
Phone: +49 391 6110 201
Fax: +49 391 6110 203
Room: N0.19

Contact Person

Annegret Frauendienst
Phone:+49 391 6110-200Fax:+49 391 6110-203

Group Page

Publications

Publications BPE group

Book Chapter (10)

  1. 251.
    Book Chapter
    Reichl, U.; Sidorenko, Y.: Dynamics of Virus-Host Cell Interaction. In: Bioinformatics: From Genomes to Therapies, pp. 861 - 898 (Ed. Lengauer, T.). Wiley-VCH, Weinheim (2007)
  2. 252.
    Book Chapter
    Ritter, J. B.; Genzel, Y.; Reichl, U.: Monitoring of Extracellular TCA Cycle Intermediates in Mammalian Cell Culture. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 603 - 605 (Ed. Smith, R.). Springer, Dordrecht, The Netherlands (2007)

Conference Paper (35)

  1. 253.
    Conference Paper
    Zoun, R.; Schallert, K.; Broneske, D.; Trifonova, I.; Chen, X.; Heyer, R.; Benndorf, D.; Saake, G.: Efficient transformation of protein sequence databases to columnar index schema. In: Database and Expert Systems Applications. DEXA 2019, pp. 67 - 72 (Ed. Anderst-Kotsis , G.). DEXA: International Conference on Database and Expert Systems Applications , Linz, Austria, August 26, 2019 - August 29, 2019. Springer, Cham, Switzerland (2019)
  2. 254.
    Conference Paper
    Duvigneau, S.; Dürr, R.; Laske, T.; Bachmann, M.; Dostert, M.; Reichl, U.; Kienle, A.: Mathematical modeling as a tool to improve influenza vaccine production processes. FOSBE 2018, Chicago, Illinois, USA, August 05, 2018 - August 08, 2018. IFAC-PapersOnLine 51 (19), pp. 1 - 4 (2018)
  3. 255.
    Conference Paper
    Rüdiger, D.; Kupke, S. Y.; Reichl, U.: A multiscale model of influenza A virus replication covering highly different infection conditions in cell cultures. IFAC-PapersOnLine 51 (19), pp. 32 - 33 (2018)
  4. 256.
    Conference Paper
    Zoun, R.; Campero Durand, G.; Schallert , K.; Patrikar, A.; Broneske, D.; Fenske, W.; Heyer, R.; Benndorf, D.; Saake, G.: Protein Identification as a Suitable Application for Fast Data Architecture. DEXA : International Conference on Database and Expert Systems Applications , Regensburg, Germany, September 03, 2018 - September 06, 2018. Database and Expert Systems Applications: DEXA 2018 International Workshops BDMICS, BIOKDD, and TIR 903, pp. 168 - 178 (2018)
  5. 257.
    Conference Paper
    Dürr, R.; Duvigneau, S.; Laske, T.; Bachmann, M.; Kienle, A.: Analyzing the Impact of Heterogeneity in Genetically Engineered Cell Lines for Influenza Vaccine Production Using Population Balance Modeling. Foundations of Systems Biology in Engineering - FOSBE 2016 — Magdeburg, Germany, 9—12 October 2016, Magdeburg, Germany, October 09, 2016 - October 12, 2016. IFAC-PapersOnLine 49 (26), pp. 225 - 230 (2016)
  6. 258.
    Conference Paper
    Kramer, B.; Tüngler, R.; Bettenbrock, K.; Conradi, C.: A compact mathematical model of mandelate racemase production and chaperone overexpression in E. coli. 8th Vienna Interantional Conference on Mathematical Modelling , Vienna, Austria, February 18, 2015 - February 20, 2015. IFAC-PapersOnLine 48 (1), pp. 23 - 28 (2015)
  7. 259.
    Conference Paper
    Rehberg, M.; Wetzel, M.; Ritter, J.; Reichl, U.: The Regulation of Glutaminolysis and Citric Acid Cycle Activity During Mammalian Cell Cultivation. 12th IFAC Symposium on Computer Applications in Biotechnology - CAB 2013, Mumbai, India, December 16, 2013 - December 18, 2013. IFAC Proceedings Volumes 46 (31), pp. 48 - 53 (2013)
  8. 260.
    Conference Paper
    Dürr, R.; Müller, T.; Isken, B.; Schulze-Horsel, J.; Reichl, U.; Kienle, A.: Distributed Modeling and Parameter Estimation of Influenza Virus Replication During Vaccine Production. MATHMOD 2012 - 7th Vienna International Conference on Mathematical Modelling, Vienna, Austria, February 15, 2012 - February 17, 2012. IFAC Proceedings Volumes 45 (2), pp. 320 - 325 (2012)
  9. 261.
    Conference Paper
    Isken, B.; Schulze-Horsel, J.; Bock, A.; Genzel, G.; Reichl, U.: Monitoring of Host-Cell Infection and Virus-Induced Apoptosis in Influenza Vaccine Production. In: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), pp. 675 - 683 (Eds. Jenkins, N.; Barron, N.; Alves, P.). 21st ESACT Meeting , Dublin, Ireland, June 07, 2009 - June 10, 2009. (2012)
  10. 262.
    Conference Paper
    Kröber, T.; Wolff, M. W.; Lehmann, S.; Zimmermann, A.; Reichl, U.: Accounting for the Entire Influenza Hemagglutinin during a Flu Vaccine Production Process. In: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), pp. 685 - 689. 21st ESACT Meeting , Dublin, Ireland, June 07, 2009 - June 10, 2009. Berlin (2012)
  11. 263.
    Conference Paper
    Lohr, V.; Rath, A.; Jordan, I.; Sandig, V.; Genzel, Y.; Reichl, U.: Avian Designer Cells AGE1.CR as Candidates for MVA and Influenza Vaccine Production. In: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), pp. 615 - 631 (Eds. Jenkins, N.; Barron, N.; Alves, P.). 21st ESACT Meeting, Dublin, Ireland, June 07, 2009 - June 10, 2009. (2012)
  12. 264.
    Conference Paper
    Öncül, A. A.; Genzel, Y.; Reichl, U.; Thévenin, D.: Flow characterization in wave bioreactors using Computational Fluid Dynamics. In: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), pp. 455 - 469 (Eds. Jenkins, N.; Barron, N.; Alves, P.). 21st ESACT Meeting, Dublin, Ireland, June 07, 2009 - June 10, 2009. Dordrecht (2012)
  13. 265.
    Conference Paper
    Roedig, J.; Rapp, E.; Hennig, R.; Schwarzer, J.; Reichl, U.: Optimized CGE-LIF-based glycan analysis for high-throughput applications. In: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), pp. 599 - 603 (Eds. Jenkins, N.; Barron, N.; Alves, P.). 21st ESACT Meeting, Dublin, Ireland, June 07, 2009 - June 10, 2009. (2012)
  14. 266.
    Conference Paper
    Schenkendorf, R.; Mangold, M.; Reichl, U.: Parameter Identification of Time-Delay Systems: A Flatness Based Approach. MATHMOD 2012 - 7th Vienna International Conference on Mathematical Modelling, Vienna, Austria, February 15, 2012 - February 17, 2012. IFAC Proceedings Volumes 45 (2), pp. 165 - 170 (2012)
  15. 267.
    Conference Paper
    Müller, T.; Dürr, R.; Isken, B.; Schulze-Horsel, J.; Reichl, U.; Kienle, A.: Population balance modelling of influenza virus replication during vaccine prodcution - Influence of apoptosis. In: 21st European Symposium on Computer Aided Process Engineering - Part A, pp. 1336 - 1340 (Eds. Pistikopoulos, E.N.; Georgiadis, M.C.; Kokossis, A.C.). ESCAPE 21 - 21st European Symposium on Computer Aided Process Engineering, Chalkidiki, Greece, May 29, 2011 - June 01, 2011. (2011)
  16. 268.
    Conference Paper
    Bock, A.; Genzel, Y.; Reichl, U.: Monitoring of Cell activity: online oxygen uptake rates in pulsed aerated cell culture. In: Cells and Culture: Proceedings of the 20th ESACT Meeting, pp. 391 - 396 (Ed. Noll, T.). 20th ESACT Meeting, Dresden, Germany, June 17, 2007 - June 20, 2007. (2010)
  17. 269.
    Conference Paper
    Genzel, Y.; Dietzsch, C.; Reichl, U.: Comparing Vero and MDCK cells for influenza A virus production in microcarrier systems. In: Cells and Culture: Proceedings of the 20th ESACT Meeting, pp. 635 - 638 (Ed. Noll, T.). 20th ESACT Meeting, Dresden, Germany, June 17, 2007 - June 20, 2007. (2010)
  18. 270.
    Conference Paper
    Öncül, A.A.; Janiga, G.; Genzel, Y.; Reichl, U.; Thévenin, D.: Two-population CFD simulation: microcarrier system for adherent cell growth in Wave Bioreactors. In: 4th International Conference on Population Balance Modelling: PBM 2010, pp. 667 - 681. 4th International Conference on Population Balance Modelling, Berlin, Germany, September 15, 2010 - September 17, 2010. (2010)
  19. 271.
    Conference Paper
    Ritter, J. B.; Genzel, Y.; Reichl, U.: Metabolite Analysis in Mammalian Cells: How to generate reliable data sets? In: Cells and Culture: Proceedings of the 20th ESACT Meeting, pp. 397 - 406 (Ed. Noll, T.). 20th ESACT Meeting, Dresden, Germany, June 17, 2007 - June 20, 2007. (2010)
  20. 272.
    Conference Paper
    Schulze-Horsel, J.; Schulze, M.; Genzel, Y.; Reichl, U.: Single-cell approach in influenza vaccine production: apoptosis and virus protein production. In: Cells and Culture: Proceedings of the 20th ESACT Meeting, pp. 25 - 28 (Ed. Noll, T.). 20th ESACT Meeting, Dresden, Germany, June 17, 2007 - June 20, 2007. (2010)
  21. 273.
    Conference Paper
    Schwarzer, J.; Rapp, E.; Reichl, U.: Glycosylation of Influenza A Virus Hemagglutinin. In: Cells and Culture: Proceedings of the 20th ESACT Meeting, pp. 621 - 624 (Ed. Noll, T.). 20th ESACT Meeting, Dresden, Germany, June 17, 2007 - June 20, 2007. (2010)
  22. 274.
    Conference Paper
    Vester, D.; Rapp, E.; Genzel, Y.; Gade, D.; Reichl, U.: Proteomic analysis of influenza A virus infected mammalian cells by 2D-DIGE. In: Cells and Culture: Proceedings of the 20th ESACT Meeting, pp. 429 - 432 (Ed. Noll, T.). 20th ESACT Meeting, Dresden, Germany, June 17, 2007 - June 20, 2007. (2010)
  23. 275.
    Conference Paper
    Wahl, A.; Sidorenko, Y.; Genzel, Y.; Reichl, U.: Metabolic flux distribution during growth of adherent growing MDCK cells in different media. In: Cells and Culture: Proceedings of the 20th ESACT Meeting, pp. 459 - 462 (Ed. Noll, T.). 20th ESACT Meeting, 2007-06-17, June 20, 2007. (2010)
  24. 276.
    Conference Paper
    Mueller, T.; Schulze-Horsel, J.; Sidorenko, Y.; Reichl, U.; Kienle, A.: Population balance modeling of influenza virus replication in MDCK cells during vaccine production. In: 18th European Symposium on Computer Aided Process Engineering: ESCAPE 18, Vol. 25, pp. 133 - 138 (Eds. Braunschweig, B.; Joulia, X.). 18th European Symposium on Computer Aided Process Engineering - ESCAPE, Lyon, France, June 01, 2008 - June 04, 2008. (2008)
  25. 277.
    Conference Paper
    Bock, A.; Reichl, U.: Closed loop control of perfusion systems in high-density cell culture. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 549 - 551 (Ed. Smith, R.). 19th ESACT Meeting, Harrogate, UK, June 05, 2005 - June 08, 2005. Springer, Dordrecht, The Netherlands (2007)
  26. 278.
    Conference Paper
    Genzel, Y.; Fischer, M.; Olmer, R. M.; Schäfer, B.; Best, C.; König, S.; Hundt, B.; Reichl, U.: Serum-free influenza vaccine production with MDCK cells in wave-bioreactor and 5L-stirred tank bioreactor. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 563 - 565 (Ed. Smith, R.). 19th ESACT Meeting , Harrogate, UK, June 05, 2005 - June 08, 2005. Springer, Dordrecht, The Netherlands (2007)
  27. 279.
    Conference Paper
    Genzel, Y.; Schulze-Horsel, J.; Möhler, L.; Sidorenko, Y.; Reichl, U.: Influenza Vaccines: Challenges in Mammalian Cell Culture Technology. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 503 - 508 (Ed. Smith, R.). 19th ESACT Meeting, Harrogate, UK, June 05, 2005 - June 08, 2005. Springer, Dordrecht, The Netherlands (2007)
  28. 280.
    Conference Paper
    Hundt, B.; Straube, S.; Schlawin, N.; Kaßner, H.; Reichl, U.: Cultivation of E-FL in Perfusion Mode Using Wave Bioreactor and Stirre-Tank Reactor for Parvovirus Vaccine Production. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 519 - 522 (Ed. Smith, R.). 19th ESACT Meeting, Harrogate, UK, June 05, 2005 - June 08, 2005. Springer, Dordrecht, The Netherlands (2007)
  29. 281.
    Conference Paper
    Pohlscheidt, M.; Langer, U.; Bödeker, B.; Paulsen, D.; Rübsamen-Waigmann, H.; Reichl, U.; Henzler, H. J.; Apeler, H.: Strategies for Large Scale Production of Parapoxvirus Ovis NZ-2. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 707 - 710 (Ed. Smith, R.). 19th ESACT Meeting, Harrogate, UK, June 05, 2005 - August 06, 2005. Springer, Dordrecht, The Netherlands (2007)
  30. 282.
    Conference Paper
    Reichl, U.: Biological Fundamentals, Models and Technologies for Vaccine Production. In: Perspectives of Research - Identification and Implementation of Research Topics by Organizations: Ringberg-Symposium Mai 2006, Vol. 7, pp. 191 - 208. Ringberg-Symposium, Kreuth, Germany, May 03, 2006 - May 05, 2006. (2007)
  31. 283.
    Conference Paper
    Schulze-Horsel, J.; Genzel, Y.; Reichl, U.: Monitoring of Cell Physiology in Influenza Vaccine Production by Flow Cytometry. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 531 - 533 (Ed. Smith, R.). 19th ESACT Meeting, Harrogate, UK, June 05, 2005 - August 06, 2005. Springer, Dordrecht, The Netherlands (2007)
  32. 284.
    Conference Paper
    Genzel, Y.; Alt, R.; Reichl, U.: Glutamine-free media for vaccine production processes. In: Animal Cell Technology meets Genomics: Proceedings ot the 18th ESACT Meeting, pp. 767 - 770 (Eds. Godia, F.; Fussenegger, M.). 18th ESACT Meeting , Granada, Spain, May 11, 2003 - May 14, 2003. (2005)
  33. 285.
    Conference Paper
    Hundt, B.; Schänzler, A.; Reichl, U.: Serum free cultivation of primary chicken embryo fibroblasts in microcarrier systems for vaccine production. In: Animal Cell Technology Meets Genomics: Proceedings of the 18th ESACT Meeting, pp. 771 - 774. 18th ESACT Meeting, Granada, Spain, May 11, 2003 - May 14, 2003. (2005)
  34. 286.
    Conference Paper
    Reichl, U.; Genzel, Y.; Möhler, L.; Sidorenko, Y.; Sann, H.: Animal cell cultures for the production of viral vaccines. In: GVC/DECHEMA Vortrags- und Diskussiontagung "Zellkulturen: vom biologischen System zum Produktionsprozess", pp. 32 - 35. GVC/DECHEMA : Vortrags- und Diskussionstagung, Bad Dürkheim, Deutschland, May 26, 2003 - May 28, 2003. (2003)
  35. 287.
    Conference Paper
    Genzel, Y.; Voges, L.; Reichl, U.: Development of bioprocess concepts on vaccine production: influenza virus as an example. In: Animal cell technology: from target to market, pp. 344 - 346 (Eds. Lindner-Olsson, E.; Chatzissavidou, N.; Luellau, E.). 17th ESACT Meeting, Tylösand, Sweden, June 10, 2001 - June 14, 2001. (2001)

Meeting Abstract (46)

  1. 288.
    Meeting Abstract
    Marichal-Gallardo, P.; Genzel, Y.; Börner, K.; Grimm, D.; Wolff, M. W.; Reichl, U.: A single-use chromatographic purification platform for viral gene transfer vectors & viral vaccines. In Proceedings Advancing Manufacture of Cell and Gene Therapies VI, 92. Advancing Manufacture of Cell and Gene Therapies VI, Loews Coronado Bay Hotel Coronado, California, USA, January 27, 2019 - January 31, 2019. (2019)
  2. 289.
    Meeting Abstract
    Bissinger, T.; Reichl, U.; Genzel, Y.; Wu, Y.; Liu, X.; Tan, W.-S.: Highly efficient influenza virus production: A MDCK-based high-cell-density process. In Vaccine Technology VII, 13. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  3. 290.
    Meeting Abstract
    Coronel, J.; Genzel, Y.; Reichl, U.; Behrendt, I.; Buergin, T.; Andereli, T.; Sandig, V.: Orbital shaken bioreactor for influenza A virus production in high cell density cultivations. In Vaccine Technology VII, 40. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  4. 291.
    Meeting Abstract
    Fortuna, A. R.; Taft, F.; Villain, L.; Wolff, M. W.; Reichl, U.: Continuous purification of cell culture-derived influenza A virus particles through pseudo- affinity membrane chromatography. In Vaccine Technology VII, 124. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  5. 292.
    Meeting Abstract
    Gränicher, G.; Genzel, Y.; Reichl, U.; John, K.; Sandig, V.; Karlas, A.: A new porcine suspension cell line (PBG.PK-21) provides efficient production for influenza and yellow fever vaccine viruses. In Vaccine Technology VII, 48. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  6. 293.
    Meeting Abstract
    Kupke, S. Y.; Riedel, D.; Frensing, T.; Zmora, P.; Reichl, U.: Single-cell analysis uncovers a novel influenza A virus-derived defective interfering particle for antiviral therapy. In Vaccine Technology VII, 133. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  7. 294.
    Meeting Abstract
    Marichal-Gallardo, P.; Fortuna, A. R.; Genzel, Y.; Wolff, M. W.; Reichl, U.: Purifying viruses with a sheet of paper: Single-use steric exclusion chromatography as a capture platform for vaccine candidates. In Vaccine Technology VII, 128. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  8. 295.
    Meeting Abstract
    Nikolay, A.; Genzel, Y.; Schwamborn, K.; Leon, A.; Reichl, U.: Flavivirus production in perfusion processes using the EB66® cell line. In Vaccine Technology VII, 80. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  9. 296.
    Meeting Abstract
    Peixoto, C.; Carvalho, S. B.; Carrondo, M. J.T.; Alves , P. M.; Fortuna, A. R.; Reichl, U.; Wolff, M. W.: Addressing the challenges of influenza virus-like particles purification. In Vaccine Technology VII, 57. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  10. 297.
    Meeting Abstract
    Rossdamm, C.; Konze, S. A.; Oberbeck, A.; Rapp, E.; Gerardy-Schahn, R.; von Itzstein, M.; Buettner, F. F. R.: CGE-LIF as a novel approach for the analysis of glycosphingolipid-derived glycans. In GLYCOBIOLOGY, 28, 144, pp. 1057 - 1058. Annual Meeting of the Society-for-Glycobiology (SFG), New Orleans, LA (USA), November 05, 2018 - November 08, 2018. (2018)
  11. 298.
    Meeting Abstract
    Taft, F.; Köhler, R.; Van Teeffelen, S.; Fortuna, A. R.; Wolff, M. W.; Reichl, U.; Villain, L.; Boulais, A.: Influenza virus capture using membrane chromatography: Improving selectivity by matrix design and pseudo-affinity ligand interactions. In Vaccine Technology VII, 75. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  12. 299.
    Meeting Abstract
    Wu, Y.; Liu, X.; Tan, W.-S.; Bissinger, T.; Genzel, Y.; Reichl, U.: Efficient influenza vaccine manufacturing: Single MDCK suspension cells in chemically defined medium. In Vaccine Technology VII, 5. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)
  13. 300.
    Meeting Abstract
    Tapia, F.; Genzel, Y.; Reichl, U.; Sandig, V.: Stirred tanks in cascades and plug-flow tubular bioreactors for continuous production of viral vaccines. In ECI Symposium Series. Integrated Continuous Biomanufacturing III, Cascais, Portugal, September 17, 2017 - September 21, 2017. (2017)
 
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