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Journal Article (7)

  1. Journal Article
    Kluge, S.; Genzel, Y.; Laus, K.; Serve, A.; Pflugmacher, A.; Peschel, B.; Rapp, E.; Reichl, U.: Ezrin and HNRNP expression correlate with increased virus release rate and early onset of virus-induced apoptosis of MDCK suspension cells. Biotechnology Journal 11 (10), pp. 1332 - 1342 (2016)
  2. Journal Article
    Frensing, T.; Pflugmacher, A.; Bachmann, M.; Peschel, B.; Reichl, U.: Impact of defective interfering particles on virus replication and antiviral host response in cell culture-based influenza vaccine production. Applied Microbiology and Biotechnology 98 (21), pp. 8999 - 9008 (2014)
  3. Journal Article
    Heldt, S.; Frensing, T.; Pflugmacher, A.; Gröpler, R.; Peschel, B.; Reichl, U.: Multiscale Modeling of Influenza A Virus Infection Supports the Development of Direct-Acting Antivirals. PLoS Computational Biology 9 (11), p. e1003372 (2013)
  4. Journal Article
    Müller, T.; Dürr, R.; Isken, B.; Schulze-Horsel, J.; Reichl, U.; Kienle, A.: Distributed modeling of human influenza a virus-host cell interactions during vaccine production. Biotechnology and Bioengineering 110 (8), pp. 2252 - 2266 (2013)
  5. Journal Article
    Peschel, B.; Frentzel, S.; Laske, T.; Genzel, Y.; Reichl, U.: Comparison of influenza virus yields and apoptosis-induction in an adherent and a suspension MDCK cell line. Vaccine 31 (48), pp. 5693 - 5699 (2013)
  6. Journal Article
    Isken, B.; Genzel, Y.; Reichl, U.: Productivity, apoptosis, and infection dynamics of influenza A/PR/8 strains and A/PR/8-based reassortants. Vaccine 30 (35), pp. 5253 - 5261 (2012)
  7. Journal Article
    Seitz, C.; Isken, B.; Heynisch, B.; Rettkowski, M.; Frensing, T.; Reichl, U.: Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host response. Applied Microbiology and Biotechnology 93 (2), pp. 601 - 611 (2012)

Conference Paper (3)

  1. Conference Paper
    Dürr, R.; Müller, T.; Isken, B.; Schulze-Horsel, J.; Reichl, U.; Kienle, A.: Distributed Modeling and Parameter Estimation of Influenza Virus Replication During Vaccine Production. MATHMOD 2012 - 7th Vienna International Conference on Mathematical Modelling, Vienna, Austria, February 15, 2012 - February 17, 2012. IFAC Proceedings Volumes 45 (2), pp. 320 - 325 (2012)
  2. Conference Paper
    Isken, B.; Schulze-Horsel, J.; Bock, A.; Genzel, G.; Reichl, U.: Monitoring of Host-Cell Infection and Virus-Induced Apoptosis in Influenza Vaccine Production. In: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), pp. 675 - 683 (Eds. Jenkins, N.; Barron, N.; Alves, P.). 21st ESACT Meeting , Dublin, Ireland, June 07, 2009 - June 10, 2009. (2012)
  3. Conference Paper
    Müller, T.; Dürr, R.; Isken, B.; Schulze-Horsel, J.; Reichl, U.; Kienle, A.: Population balance modelling of influenza virus replication during vaccine prodcution - Influence of apoptosis. In: 21st European Symposium on Computer Aided Process Engineering - Part A, pp. 1336 - 1340 (Eds. Pistikopoulos, E.N.; Georgiadis, M.C.; Kokossis, A.C.). ESCAPE 21 - 21st European Symposium on Computer Aided Process Engineering, Chalkidiki, Greece, May 29, 2011 - June 01, 2011. (2011)

Talk (4)

  1. Talk
    Heldt, S.; Isken, B.; Pflugmacher, A.; Frensing, T.; Reichl, U.: Multi-scale modeling of influenza virus infection elucidates the performance of antivirals. 1st Workshop on Virus Dynamics (DECHEMA), Frankfurt/Main, Germany (2013)
  2. Talk
    Heldt, S.; Peschel, B.; Frensing, T.; Reichl, U.: Multiscale modeling of influenza virus infection supports the development of antiviral drugs. 14th International Conference on Systems Biology , Copenhagen (Denmark) (2013)
  3. Talk
    Dürr, R.; Müller, T.; Isken, B.; Schulze-Horsel, J.; Reichl, U.; Kienle, A.: Distributed Modeling and Parameter Estimation of Influenza Virus Replication During Vaccine Production. MATHMOD 2012 - 7th Vienna International Conference on Mathematical Modelling, Vienna, Austria (2012)
  4. Talk
    Genzel, Y.; Janke, R.; Isken, B.; Rödig, J.; Rapp, E.; Lohr, V.; Behrendt, I.; Scharfenberg, K.; Kamen, A.; Schiedner, G. et al.; Jordan, I.; Reichl, U.: Influenza virus production: characteristics of different producer cell lines. 10th PEACe 2011, Cascais, Portugal (2011)

Poster (6)

  1. Poster
    Heldt, S.; Peschel, B.; Pflugmacher, A.; Frensing, T.; Reichl, U.: A multi-scale model of influenza virus infection elucidates the performance of antivirals. 23rd Annual Meeting of the Society for Virology , Kiel, Germany (2013)
  2. Poster
    Heldt, S.; Isken, B.; Pflugmacher, A.; Frensing, T.; Reichl, U.: A multi-scale model of influenza virus infection elucidates the performance of antivirals. 23rd Annual Meeting of the Society for Virology, Kiel, Germany (2013)
  3. Poster
    Kluge, S.; Genzel, Y.; Herche, K. C.; Peschel, B.; Pflugmacher, A.; Rapp, E.; Scharfenberg, K.; Reichl, U.: Virus-Wirtszellinteraktionen einer adhärenten Zelllinie und ihrer adaptierten Suspensionszelllinie: Eine Proteom-Studie. Effiziente Verfahren und Anlagen in der Bioverfahrenstechnik und Lebensmittelbiotechnologie (Himmelfahrtstagung der DECHEMA 2013), Bad Wildungen, Germany (2013)
  4. Poster
    Frensing, T.; Seitz, C.; Isken, B.; Heynisch, B.; Kochs, C.; Reichl, U.: Influence of Host Cell Defence during Influenza Vaccine Production in Cell Culture. 22nd ESACT Meeting, Vienna, Austria (2011)
  5. Poster
    Frensing, T.; Seitz, C.; Isken, B.; Heynisch, B.; Kochs, C.; Reichl, U.: Influence of Host Cell Defence during Influenza Vaccine Production in Cell Culture. 22nd ESACT Meeting, Vienna, Austria (2011)
  6. Poster
    Schulze-Horsel, J.; Isken, B.; Bock, A.; Genzel, Y.; Reichl, U.: Monitoring of host-cell infection and apoptosis in influenza vaccine production. 21st ESACT Meeting, Dublin, Ireland (2009)
 
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