Publications of S. Klamt

Journal Article (111)

2010
Journal Article
Klamt, S., Flassig, R., & Sundmacher, K. (2010)TRANSWESD: inferring cellular networks with transitive reductionBioinformatics, 26 (17), 2160–2168doi: 10.1093/bioinformatics/btq342.
Journal Article
Samaga, R., von Kamp, A., & Klamt, S. (2010)Computing Combinatorial Intervention Strategies and Failure Modes in Signaling NetworksJournal of Computational Biology, 17 (1), 39–53doi: 10.1089/cmb.2009.0121.
2009
Journal Article
Klamt, S., Haus, U.-U., & Theis, F. (2009)Hypergraphs and cellular networksPLoS Computational Biology, 5 (5), e1000385doi: 10.1371/journal.pcbi.1000385.
Journal Article
Klamt, S. & von Kamp, A. (2009)Computing Paths and Cycles in Biological Interaction GraphsBMC Bioinformatics, 10, 181doi: 10.1186/1471-2105-10-181.
Journal Article
Poltz, R., Franke, R., Schweitzer, K., Klamt, S., Gilles, E. D., & Naumann, M. (2009)Logical network of genotoxic stress-induced NF-kB signal transduction predicts putative target structures for therapeutic intervention strategiesAdvances and Applications in Bioinformatics and Chemistry, 2, 125–138doi: 10.2147/AABC.S8211.
Journal Article
Saez-Rodriguez, J., Alexopoulos, L. G., Epperlein, J., Samaga, R., Lauffenburger, D. A., Klamt, S., & Sorger, P. K. (2009)Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transductionMolecular Systems Biology, 5, 331doi: 10.1038/msb.2009.87.
Journal Article
Samaga, R., Saez-Rodriguez, J., Alexopoulos, L. G., Sorger, P. K., & Klamt, S. (2009)The logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput dataPLoS Computational Biology, 5 (8), e1000438doi: 10.1371/journal.pcbi.1000438.
Journal Article
Wittmann, D. M., Krumsiek, J., Saez, J., Lauffenburger, D. A., Klamt, S., & Theis, F. (2009)Transforming Boolean models to continuous models: methodology and application to T-cell receptor signalingBMC Systems Biology, 3, 98doi: 10.1186/1752-0509-3-98.
2008
Journal Article
Franke, R., Mueller, M., Wundrack, N., Gilles, E. D., Klamt, S., Kaehne, T., & Naumann, M. (2008)Host-pathogen systems biology: Logical modelling of hepatocyte growth factor and Helicobacter pylori induced c-Met signal transductionBMC Systems Biology, 2, 4doi: 10.1186/1752-0509-2-4.
Journal Article
Haus, U.-U., Klamt, S., & Stephen, T. (2008)Computing knock-out strategies in metabolic networksJournal of Computational Biology, 15 (3), 259–268doi: 10.1089/cmb.2007.0229.
Journal Article
Klamt, S., Grammel, H., Straube, R., Ghosh, R., & Gilles, E. D. (2008)Modeling the electron transport chain of purple non-sulfur bacteriaMolecular Systems Biology, 4, 156doi: 10.1038/msb4100191.
Journal Article
Saez-Rodriguez, J., Hammerle-Fickinger, A., Dalal, O., Klamt, S., Gilles, E. D., & Conradi, C. (2008)Multistability of signal transduction motifsIET Systems Biology, 2 (2), 80–93doi: 10.1049/iet-syb:20070012.
2007
Journal Article
Beste, D. J., Hooper, T., Stewart, G., Bonde, B., Avignone-Rossa, C., Bushell, M. E., Wheeler, P., Klamt, S., Kierzek, A. M., & McFadden, J. (2007)GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosis metabolismGenome Biology, 8, R89doi: 10.1186/gb-2007-8-5-r89.
Journal Article
Klamt, S., Saez-Rodriguez, J., & Gilles, E. D. (2007)Structural and functional analysis of cellular networks with CellNetAnalyzerBMC Systems Biology, 1, 2doi: 10.1186/1752-0509-1-2.
Journal Article
Saez-Rodriguez, J., Simeoni, L., Lindquist, J., Hemenway, R., Bommhardt, U., Arndt, B., Haus, U. U., Weismantel, R., Gilles, E. D., Klamt, S., & Schraven, B. (2007)A logical model provides insights into T cell receptor signalingPLoS Computational Biology, 3, e163doi: 10.1371/journal.pcbi.0030163.
2006
Journal Article
Klamt, S. (2006)Generalized concept of minimal cut sets in biochmical networksBiosystems, 83 (2-3 ), 233–247doi: 10.1016/j.biosystems.2005.04.009.
Journal Article
Klamt, S., Saez-Rodriguez, J., Lindquist, J., Simeoni, L., & Gilles, E. D. (2006)A methodology for the structural and functional analysis of signaling and regulatory networksBMC Bioinformatics, 7, 56doi: 10.1186/1471-2105-7-56.
Journal Article
Saez-Rodriguez, J., Mirschel, S., Hemenway, R., Klamt, S., Gilles, E. D., & Ginkel, M. (2006)Visual set-up of logical models of signaling and regulatory networks with ProMoTBMC Bioinformatics, 7, 506doi: 10.1186/1471-2105-7-506.
2005
Journal Article
Klamt, S., Gagneur, J., & von Kamp, A. (2005)Algorithmic approaches for computing elementary modes in large biochemical reaction networksIEE Proceedings - Systems Biology, 152 (4), 249–255doi: 10.1049/ip-syb:20050035.
2004
Journal Article
Gagneur, J. & Klamt, S. (2004)Computation of elementary modes: a unifying framework and the new binary approachBMC Bioinformatics, 5, 175doi: 10.1186/1471-2105-5-175.
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