Publications of Robert Flassig

Journal Article (20)

2020
Journal Article
Fachet, M., Witte, C., Flassig, R., Rihko-Struckmann, L., McKie-Krisberg, Z., Polle, J., & Sundmacher, K. (2020)Reconstruction and analysis of a carbon-core metabolic network for Dunaliella salinaBMC Bioinformatics, 21, 1doi: 10.1186/s12859-019-3325-0.
Journal Article
Vogel , S. K., Wölfer, C., Ramirez-Diaz, D. A., Flassig, R., Sundmacher, K., & Schwille, P. (2020)Symmetry breaking and emergence of directional flows in minimal actomyosin corticesCells, 9 (6), 1432doi: 10.3390/cells9061432.
2019
Journal Article
Wölfer, C., Mangold, M., & Flassig, R. (2019)Towards Design of Self‐Organizing Biomimetic SystemsAdvanced Biosystems, 3 (6), 1800320doi: 10.1002/adbi.201800320.
2018
Journal Article
Buchbinder, J. H., Pischel, D., Sundmacher, K., Flassig, R., & Lavrik, I. N. (2018)Quantitative single cell analysis uncovers the life/death decision in CD95 networkPLOS Computational Biology, 14 (9), e1006368doi: 10.1371/journal.pcbi.1006368.
Journal Article
Kaiser, N. M., Flassig, R., & Sundmacher, K. (2018)Reactor-Network Synthesis via Flux Profile AnalysisChemical Engineering Journal, 335, 1018–1030doi: 10.1016/j.cej.2017.09.051.
Journal Article
Pischel, D., Buchbinder, J., Sundmacher, K., Lavrik, I., & Flassig, R. (2018)A guide to automated apoptosis detection: How to make sense of imaging flow cytometry dataPLoS ONE, 13 (5), e0197208doi: 10.1371/journal.pone.0197208.
2017
Journal Article
Fachet, M., Flassig, R., Rihko-Struckmann, L., & Sundmacher, K. (2017)Carotenoid Production Process Using Green Microalgae of the Dunaliella Genus: Model-Based Analysis of Interspecies VariabilityIndustrial and Engineering Chemistry Research, 56 (45), 12888–12898doi: 10.1021/acs.iecr.7b01423.
Journal Article
Kaiser , N. M., Jokiel, M., McBride, K., Flassig, R., & Sundmacher, K. (2017)Optimal Reactor Design via Flux Profile Analysis for an Integrated Hydroformylation ProcessIndustrial and Engineering Chemistry Research, 56 (40), 11507–11518doi: 10.1021/acs.iecr.7b01939.
Journal Article
Pischel, D., Sundmacher, K., & Flassig, R. (2017)Efficient simulation of intrinsic, extrinsic and external noise in biochemical systemsBioinformatics, 33 (14), i319–i324doi: 10.1093/bioinformatics/btx253.
2016
Journal Article
Flassig, R., Fachet, M., Höffner, K., Barton, P. I., & Sundmacher, K. (2016)Dynamic flux balance modeling to increase the production of high-value compounds in green microalgaeBiotechnology for Biofuels, 9 (165), 1–12doi: 10.1186/s13068-016-0556-4.
Journal Article
Kaiser, N. M., Flassig, R., & Sundmacher, K. (2016)Probabilistic Reactor Design in the Framework of Elementary Process FunctionsComputers & Chemical Engineering, 45–59doi: 10.1016/j.compchemeng.2016.06.008.
2015
Journal Article
Do Thi, Q. N., Varničić, M., Flassig, R., Vidaković-Koch, T., & Sundmacher, K. (2015)Dynamic and Steady State 1-D Model of Mediated Electron Transfer in a Porous Enzymatic ElectrodeBioelectrochemistry, 106 (Part A), 3–13doi: 10.1016/j.bioelechem.2015.07.007.
Journal Article
Flassig, R., Migal, I., van der Zalm, E., Rihko-Struckmann, L., & Sundmacher, K. (2015)Rational selection of experimental readout and intervention sites for reducing uncertainties in computational model predictionsBMC Bioinformatics, 16, 13doi: 10.1186/s12859-014-0436-5.
Journal Article
Pirwitz, K., Flassig, R., Rihko-Struckmann, L., & Sundmacher, K. (2015)Energy and operating cost assessment of competing harvesting methods for D. salina in a ß-carotene production processAlgal Research, 12, 161–169doi: 10.1016/j.algal.2015.08.016.
2014
Journal Article
Fachet, M., Flassig, R., Rihko-Struckmann, L., & Sundmacher, K. (2014)A dynamic growth model of Dunaliella salina: Parameter identification and profile likelihood analysisBioresource Technology, 173, 21–31doi: 10.1016/j.biortech.2014.08.124.
Journal Article
Flassig, R., Maubach, G., Täger, C., Sundmacher, K., & Naumann, M. (2014)Experimental design, validation and computational modeling uncover DNA damage sensing by DNA-PK and ATMMolecular BioSystems, 10 (7), 1978–1986doi: 10.1039/C4MB00093E.
2013
Journal Article
Flassig, R., Heise, S., Sundmacher, K., & Klamt, S. (2013)An effective framework for reconstructing gene regulatory networks from genetical genomics data.Bioinformatics, 29 (2), 246–254doi: 10.1093/bioinformatics/bts679.
Journal Article
Pinna, A., Heise, S., Flassig, R., de la Fuente, A., & Klamt, S. (2013)Reconstruction of large-scale regulatory networks based on perturbation graphs and transitive reduction: improved methods and their evaluationBMC Systems Biology, 7, 73doi: 10.1186/1752-0509-7-73.
2012
Journal Article
Flassig, R. & Sundmacher, K. (2012)Optimal design of stimulus experiments for robust discrimination of biochemical reaction networksBioinformatics, 28 (23), 3089–3096doi: 10.1093/bioinformatics/bts585.
2010
Journal Article
Klamt, S., Flassig, R., & Sundmacher, K. (2010)TRANSWESD: inferring cellular networks with transitive reductionBioinformatics, 26 (17), 2160–2168doi: 10.1093/bioinformatics/btq342.
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