Publications of Sascha Young Kupke

Poster (27)

2022
Poster
Hein, M., Chawla, A., Arora , P., Cattaneo, M., Winkler, M., Pöhlmann, S., Genzel, Y., Kupke, S. Y., & Reichl, U.Production of influenza A virus-derived defective interfering particles for antiviral therapy in a high cell density perfusion cultivationPresented at: 27th ESACT MeetingLisbon (Portugal), June 26, 2022.
Poster
Küchler, J., Püttker, S., Lahmann, P., Genzel, Y., Kupke, S. Y., Benndorf, D., & Reichl, U.Absolute quantification of viral proteins during single-round replication of MDCK suspension cellsPresented at: Proteomic Forum 2022Leipzig (Germany), April 3, 2022.
Poster
Kupke, S. Y., Hein, M. D., Bdeir, N., Rand, U., Marichal-Gallardo, P., Cicin-Sain, L., Bruder, D., Pöhlmann, S., Schughart, K., & Reichl, U.Influenza A Virus Defective Interfering Particles for Antiviral Treatment of the Influenza Disease and COVID-19Presented at: 31st Annual Meeting of the Society for Virologyonline, March 30, 2022.
Poster
Kupke, S. Y., Hein, M., Bdeir, N., Rand, U., Marichal-Gallardo, P., Cicin-Sain, L., Bruder, D., Pöhlmann, S., Schughart, K., & Reichl, U.Influenza A Virus Defective Interfering Particles for Antiviral Treatment of the Influenza Disease and COVID-19Presented at: Vaccine Technology VIIISitges (Spain), June 12, 2022.
Poster
Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Long-Term Propagation of Influenza A Virus and Its Defective Interfering Particles: Analyzing Dynamic Competition to Select Antiviral CandidatesPresented at: Vaccine Technology VIIISitges (Spain), June 12, 2022.
Poster
Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Semi-Continuous propagation of Influenza A virus and its defective interfering particles: Analyzing the dynamic competition to select antiviral candidatesPresented at: 27th ESACT MeetingLisbon (Portugal), June 26, 2022.
2021
Poster
Pelz, L., Rüdiger, D., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Semi-continuous propagation of influenza A virus and its defective interfering particles - analyzing the dynamic competition to select antiviral candidatesPresented at: 30th Annual Meeting of the Society for Virologyonline, March 24, 2021.
2020
Poster
Kupke, S. Y., Hein, M. D., Kollmus, H., Marichal-Gallardo, P., Schughart, K., & Reichl, U.The novel influenza A virus defective interfering particle "OP7" as an antiviral agent: discovery, production, and animal trialsPresented at: The seventh ESWI Influenza ConferenceVirtual Meeting, December 6, 2020.
2019
Poster
Kupke, S. Y., Riedel, D., Frensing, T., Zmora, P., & Reichl, U.A novel type of defective interfering particle for antiviral therapyPresented at: 26th ESACT MeetingCopenhagen, Denmark, May 5, 2019.
Poster
Rüdiger, D., Laske, T., Kupke, S. Y., & Reichl, U.A multiscale model of defective interfering particle replicationPresented at: FOSBE 2019Valencia, Spain, October 15, 2019.
2018
Poster
Rüdiger, D., Kupke, S. Y., & Reichl, U.A multiscale model of influenza A virus replication covering highly different infection conditions in cell culturesPresented at: Foundations of Systems Biology in Engineering - 7th FOSBE 2018Oak Brook, Illinois, USA, August 5, 2018.
2016
Poster
Rüdiger, D., Heldt, S., Kupke, S. Y., & Reichl, U.Stochastic multiscale modeling of influenza virus production in cell cultures. Poster presented at 6th IFAC Conference on Foundations of Systems Biology in EngineeringPresented at: 6th IFAC Conference on Foundations of Systems Biology in Engineering (FOSBE)Magdeburg, Germany, October 9, 2016.
Poster
Rüdiger, D., Heldt, S., Kupke, S. Y., & Reichl, U.Stochastic multiscale modeling of influenza virus production in cell culturesPresented at: 6th IFAC Conference on Foundations of Systems Biology in Engineering (FOSBE)Magdeburg, Germany, October 9, 2016.
2015
Poster
Kupke, S. Y., Heldt, F. S., Frensing, T., & Reichl, U.Single Cell Analysis of Influenza A Virus-infected Cells for the Optimization of Cell Culture-based Vaccine Manufacturing ProcessesPresented at: ESACT 2015Barcelona, Spain, May 31, 2015.

Thesis - PhD (1)

2020
Thesis - PhD
Kupke, S. Y. (2020)Single-cell analysis of influenza A virus replication: sources of cell-to-cell heterogeneity and discoverey of a novel type of defective interfering particlePhD Thesis, Otto-von-Guericke-Universität, Magdeburgdoi: 10.25673/32916.

Patent (1)

2020
Patent
Kupke, S. Y., Frensing, T., Zmora, P., & Reichl, U. (2020)Protective Interfering Nucleic Acid Molecule And Virus - Like Particle, Virsl Vector, or Virus Particle Containing the same as well as Pharmaceutical Composition Containing the Protective Interfering Nucleic Acid and its use.

Preprint (1)

2021
Preprint
Pelz, L., Rüdiger, D., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U. (2021)Semi-continuous propagation of influenza A virus and its defective interfering particles: analyzing the dynamic competition to select candidates for antiviral therapybioRxivdoi: 10.1101/2021.02.08.430251 .
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