Publications of Sascha Young Kupke

Kupke, S. Y., Riedel, D., Frensing, T., Zmora, P., & Reichl, U. (2018)Single-cell analysis uncovers a novel influenza A virus-derived defective interfering particle for antiviral therapyIn: Vaccine Technology VII, 133.

Pelz, L., Rüdiger, D., Hein, M., Böhme, J., Bälkner, M., Kershaw, O., Marichal-Gallardo, P., Gruber, A., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U.Engineered defective interfering particles of influenza A virus for antiviral treatmentPresented at: 33^rd Annual Meeting of the Society for Virology (GfV)Vienna (Austria), March 25, 2023.

Dogra, T., Pelz, L., Boehme, J. D., Baelkner, M., Kershaw, O., Marichal-Gallardo, P., Gruber, A. D., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U.Genetically engineered defective interfering particles of influenza A virus for antiviral treatment and vaccinationPresented at: 17^th Vaccine CongressGlasgow (Scotland), September 24, 2023.

Dogra, T., Pelz, L., Rüdiger, D., Kupke, S. Y., & Reichl, U.Reverse genetics for Influenza a virus to generate genetically engineered defective interfering particles for antiviral treatment and vaccinationPresented at: Vir-AI-DIP Workshop Hamburg (Germany), July 18, 2023.

Küchler, J., Opitz, P., Rüdiger, D., Kupke, S. Y., Genzel, Y., Benndorf, D., & Reichl, U.Absolute quantification of influenza A virus proteins during single-round replication in different host cellsPresented at: 6^th Workshop on Virus DynamicsNagoya (Japan), July 4, 2023.

Kupke, S. Y., Dogra, T., Pelz, L., Hein, M. D., Ndeir, N., Rand, U., Boehme, J., Baelkner, M., Kershaw, O., Winkler, M., Cicin-Sain, L., Bruder, D., Pöhlmann, S., & Reichl, U.Influenza A virus defective interfering particles as antiviral agentsPresented at: 32^nd Annual Meeting of the Society for Virology (GfV)Ulm (Germany), March 28, 2023.

Pelz, L., Dogra, T., Boehme, J. D., Hein, M. D., Marichal-Gallardo, P., Genzel, Y., Bruder, D., Kupke, S. Y., & Reichl, U.Influenza A virus OP7 defective interfering particles: Cell culture-based production and antiviral efficacy in vivoPresented at: Cell Culture Engineering (CCE) XVIII Cancun (Mexico), April 23, 2023.

Pelz, L., Genzel, Y., Kupke, S. Y., & Reichl, U.In-depth characterization and cell culture-based production of influenza A virus defective interfering particlesPresented at: ACTIP fellowship sessionDublin (Ireland), October 11, 2023.

Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. D., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Semi-continuous Propagation of Influenza A Virus and Its Defective Interfering Particles: Analyzing the Dynamic Competition To Select Candidates for Antiviral TherapyPresented at: Vir-AI-DIP WorkshopHamburg (Germany), July 18, 2023.

Rüdiger, D., Küchler, J., Piasecka, J., Pontes, C., Kupke, S. Y., & Reichl, U.OP7, a defective interfering particle with mutations: in vitro infection experiments, intracellular model, impact of mutations and mode of antiviral actionPresented at: 6^th Workshop on Virus DynamicsNagoya (japan), July 4, 2023.

Rüdiger, D., Pelz, L., Hein, M. D., Kupke, S. Y., & Reichl, U.Multiscale model of influenza A virus and defective interfering particle co-infection in animal cell culturePresented at: Vir-AI-DIP WorkshopHamburg (Germany), July 18, 2023.

Hein, M., Chawla, A., Arora , P., Cattaneo, M., Winkler, M., Pöhlmann, S., Schughart, K., Genzel, Y., Kupke, S. Y., & Reichl, U.Production of influenza A virus defective interfering particles in a high cell density perfusion cultivation with continuous virus harvestingPresented at: Vaccine Technology VIIISitges (Spain), June 12, 2022.

Hein, M., Dogra, T., Arora , P., Rand , U., Genzel, Y., Cattaneo, M., Winkler, M., Cicin-Sain, L., Bruder, D., Schughart, K., Pöhlmann, S., Kupke, S. Y., & Reichl, U.Influenza A Virus-Derived Defective Interfering Particles for Antiviral TreatmentPresented at: 27th ESACT MeetingLisbon (Portugal), June 26, 2022.

Kupke, S. Y., Hein, M. D., Bdeir, N., Rand, U., Marichal-Gallardo, P., Cicin-Sain, L., Bruder, D., Pöhlmann, S., Schughart, K., & Reichl, U.Influenza A Virus Defective Interfering Particles for Antiviral Treatment of the Influenza Disease and COVID-19Presented at: 31st Annual Meeting of the Society for Virologyonline, March 30, 2022.

Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Long-Term Propagation of Influenza A Virus and Its Defective Interfering Particles: Analyzing Dynamic Competition to Select Antiviral CandidatesPresented at: Vaccine Technology VIIISitges (Spain), June 12, 2022.

Pelz, L., Rüdiger, D., Dogra, T., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Semi-Continuous propagation of Influenza A virus and its defective interfering particles: Analyzing the dynamic competition to select antiviral candidatesPresented at: 27th ESACT MeetingLisbon (Portugal), June 26, 2022.

Rüdiger, D., Küchler, J., Pontes, C., Kupke, S. Y., & Reichl, U.Modeling the intracellular replication of a new type of defective interfering particle of influenza virus with genomic nucleotide substitutionsPresented at: 12th European Conference on Mathematical and Theoretical BiologyHeidelberg (Germany), September 19, 2022.

Rüdiger, D., Pelz, L., Hein, M. D., Kupke, S. Y., & Reichl, U.Multiscale model of influenza A virus and defective interfering particle co-infection in animal cell culturePresented at: 5th Workshop on Virus Dynamicsvirtual, October 4, 2021.

Pelz, L., Rüdiger, D., Alnaji, F. G., Genzel, Y., Brooke, C. B., Kupke, S. Y., & Reichl, U.Evolution and selection of influenza a virus defective interfering particles in a semi-continuous production system for the use as antiviralPresented at: The seventh ESWI Influenza ConferenceVirtual Meeting, December 6, 2020.

Rüdiger, D., Pelz, L., Hein, M., Kupke, S. Y., & Reichl, U.Multiscale model of DIP replication and its effects on influenza A virus infection in animal cell culturePresented at: Society for Mathematical Biology 2020 Annual MeetingVirtual Meeting, August 17, 2020.