Publications of Timo Frensing

Kupke, S. Y., Heldt, S., Frensing, T., & Reichl, U.Heterogeneity in Influenza A Virus Infection Unveiled by Single-Cell Analysis and Stochastic Mathemeatical ModelingPresented at: Single Cell Technologies 2016Frankfurt/Main, April 6, 2016.

Kupke, S. Y., Heldt, S., Frensing, T., & Reichl, U.Single-Cell Analysis of Influenza A Virus-Infected Cells for the Optimization of Cell Culture-Based Vaccine ProductionPresented at: Vaccine Technology VIAlbufeira, Portugal, June 12, 2016.

Laske, T., Bachmann, M., Frensing, T., & Reichl, U.Model-based analysis of influenza A virus replication in genetically modified cell lines elucidates virus-host cell interactionsPresented at: 1st ESACT Frontiers RetreatLyon, France, October 20, 2016.

Frensing, T.Impact of virus-host cell interactions on cell culture-based influenza vaccine productionPresented at: Protein Expression in Animal Cells (PEACE) ConferenceUSA, San Diego, September 20, 2015.

Frensing, T.Single-cell analysis and stochastic modeling reveal large cell-to-cell variability in the cell culture-based production of influenza A virusPresented at: ESACT 2015Barcelona, Spain, May 30, 2015.

Laske, T., Heldt, F. S., Frensing, T., & Reichl, U.Analyzing the dynamics of influenza A virus replication in the presence of defective interfering RNAsPresented at: 2nd Workshop on Virus Dynamics Toronto, Ontario, Canada, July 17, 2015.

Heldt, S., Frensing, T., & Reichl, U.The multiscale nature of influenza A virus infection and its implications for modeling antiviral therapyPresented at: The Joint Annual Meeting of the Japanese Society for Mathematical Biology and the Society for Mathematical BiologyOsaka, Japan, July 28, 2014.

Frensing, T.Continuous cell culture-based influenza vaccine productionPresented at: 3rd Workshop European Network on Viral Vaccine Processes (ENVVP)Frankfurt/Main, November 25, 2013.

Heldt, S., Isken, B., Pflugmacher, A., Frensing, T., & Reichl, U.Multi-scale modeling of influenza virus infection elucidates the performance of antiviralsPresented at: 1st Workshop on Virus Dynamics (DECHEMA)Frankfurt/Main, Germany, July 15, 2013.

Heldt, S., Peschel, B., Frensing, T., & Reichl, U.Multiscale modeling of influenza virus infection supports the development of antiviral drugsPresented at: 14th International Conference on Systems Biology Copenhagen (Denmark), August 30, 2013.

Heldt, F. S., Frensing, T., & Reichl, U.Elucidating bottlenecks in influenza virus replication to optimize vaccine productionPresented at: International Conference on the Systems Biology of Human DiseaseHeidelberg, Germany, May 2, 2012.

Heynisch, B., Frensing, T., Seitz, C., Genzel, Y., & Reichl, U.Analysis of the impact of innate immunity of MDCK cells on virus replication in influenza vaccine productionPresented at: ECAB 2011Berlin, September 26, 2011.

Frensing, T., Seitz, C., Heynisch, B., & Reichl, U.Influence of Host Cell Defence during Influenza Vaccine Production in MDCK CellsPresented at: Vaccine Technology IIIPuerto Vallarta, Mexiko, June 6, 2010.

Heynisch, B., Frensing, T., Seitz, C., & Reichl, U.Induction of innate immunity signaling pathways in MDCK cells and their relevance in a bioprocess for influenza vaccine productionPresented at: Molecular Interactions 2010Berlin, September 15, 2010.

Seitz, C., Frensing, T., Heynisch, B., & Reichl, U.Einfluss der zelleigenen Pathogenabwehr auf die Influenza-Impfstoffproduktion in MDCK-ZellenPresented at: Dechema JahrestagungAachen, Germany, September 20, 2010.

Laske, T., Bachmann, M., Dostert, M., Frensing, T., Karlas, A., Wirth, D., & Reichl, U.Modeling reveals changes in key parameters of infuenza A virus replication in engineered cell linesPresented at: 11th Annual International Conference on Systems Biology of Human DiseasesLos Angeles, USA, June 4, 2018.

Laske, T., Bachmann, M., Frensing, T., & Reichl, U.Model-based analysis of influenza A virus replication in genetically modified cell lines elucidates virus-host cell interactionsPresented at: 17th International Conference on Systems Biology (ICSB)Barcelona, Spain, September 16, 2016.

Laske, T., Heldt, F. S., Hoffmann, H., Frensing, T., & Reichl, U.Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAsPresented at: 26th Annual Meeting of the Society for VirologyMünster, Germany, April 6, 2016.

Bachmann, M., Breitwieser, T., Lipps , C., Wirth, D., Jordan, I., Rose, T., Sandig, V., Reichl, U., & Frensing, T.Impaired antiviral response supports viral vaccine production in adenoviral transformed designer cell linesPresented at: 25th Annual Meeting of the Society for VirologyBochum, Germany, March 18, 2015.

Bachmann, M., Breitwieser, T., Lipps, C., Wirth, D., Jordan, I., Rose, T., Sandig, V., Reichl, U., & Frensing, T.Impaired antiviral response supports influenza vaccine production in adenoviral transformed designer cell linesPresented at: ESACTBarcelona, May 31, 2015.