Search results

Journal Article (6)

2021
Journal Article
Hein, M. D.; Kollmus, H.; Marichal-Gallardo, P.; Püttker, S.; Benndorf, D.; Genzel, Y.; Schughart, K.; Kupke, S. Y.; Reichl, U.: OP7, a novel influenza A virus defective interfering particle: production, purification, and animal experiments demonstrating antiviral potential. Applied Microbiology and Biotechnology 105, pp. 129 - 146 (2021)
2020
Journal Article
Kupke, S. Y.; Ly, L.-H.; Börno, S. T.; Ruff, A.; Timmermann, B.; Vingron, M.; Haas , S.; Reichl, U.: Single-Cell Analysis Uncovers a Vast Diversity in Intracellular Viral Defective Interfering RNA Content Affecting the Large Cell-to-Cell Heterogeneity in Influenza A Virus Replication. Viruses 12 (1), 71 (2020)
2019
Journal Article
Kupke, S. Y.; Riedel, D.; Frensing, T.; Zmora, P.; Reichl, U.: A Novel Type of Influenza A Virus-Derived Defective Interfering Particle with Nucleotide Substitutions in Its Genome. Journal of Virology 93 (4), 01786-18 (2019)
Journal Article
Rüdiger, D.; Kupke, S. Y.; Laske, T.; Zmora, P.; Reichl, U.: Multiscale modeling of influenza A virus replication in cell cultures predicts infection dynamics for highly different infection conditions. PLoS Computational Biology 15 (2), e1006819 (2019)
2016
Journal Article
Frensing, T.; Kupke, S. Y.; Bachmann, M.; Fritzsche, S.; Gallo Ramirez, L. E.; Reichl, U.: Influenza virus intracellular replication dynamics, release kinetics, and particle morphology during propagation in MDCK cells. Applied Microbiology and Biotechnology 100 (16), pp. 7181 - 7192 (2016)
2015
Journal Article
Heldt, F. S.; Kupke, S. Y.; Dorl, S.; Frensing, T.; Reichl, U.: Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection. Nature Communications 6, 8938 (2015)

Conference Paper (1)

2018
Conference Paper
Rüdiger, D.; Kupke, S. Y.; Reichl, U.: A multiscale model of influenza A virus replication covering highly different infection conditions in cell cultures. IFAC-PapersOnLine 51 (19), pp. 32 - 33 (2018)

Meeting Abstract (2)

2019
Meeting Abstract
Hein, M.; Tapia, F.; Genzel, Y.; Kupke, S. Y.; Reichl, U.: Continuous mode of production for two classes of defective interfering influenza A virus particles as antiviral candidates. In Integrated Continuous Biomanufacturing IV, 76. Biomanufact IV, Ocean Edge Resort Brewster (Cape Cod), Massachusetts, USA , October 06, 2019 - October 10, 2019. (2019)
2018
Meeting Abstract
Kupke, S. Y.; Riedel, D.; Frensing, T.; Zmora, P.; Reichl, U.: Single-cell analysis uncovers a novel influenza A virus-derived defective interfering particle for antiviral therapy. In Vaccine Technology VII, 133. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)

Talk (9)

2020
Talk
Pelz, L.; Rüdiger, D.; Alnaji, F. G.; Genzel, Y.; Brooke, C. B.; Kupke, S. Y.; Reichl, U.: Evolution and selection of influenza a virus defective interfering particles in a semi-continuous production system for the use as antiviral. The seventh ESWI Influenza Conference, Virtual Meeting (2020)
Talk
Rüdiger, D.; Pelz, L.; Hein, M.; Kupke, S. Y.; Reichl, U.: Multiscale model of DIP replication and its effects on influenza A virus infection in animal cell culture. Society for Mathematical Biology 2020 Annual Meeting, Virtual Meeting (2020)
2019
Talk
Kupke, S. Y.; Riedel, D.; Frensing, T.; Zmora, P.; Reichl, U.: A novel type of defective interfering particle for antiviral therapy. 26th ESACT Meeting, Copenhagen, Denmark (2019)
Talk
Rüdiger, D.; Laske, T.; Kupke, S. Y.; Reichl, U.: Multiscale model of DIP interference and production during. 4th Workshop on Virus Dynamics, Paris, France (2019)
2018
Talk
Kupke, S. Y.: Single-Cell analysis uncover a novel influenza A virus-derived defective interfering particle for antiviral therapy. Vaccine Technology VII, Mont Tremblant, Canada (2018)
2017
Talk
Rüdiger, D.; Kupke, S. Y.; Zmora, P.; Reichl, U.: Multiscale model of influenza virus infection predicts viral release dynamics in cell cultures for a wide range of infection conditions. 3rd Workshop on Virus Dynamics, Heidelberg, Germany (2017)
2016
Talk
Kupke, S. Y.; Heldt, S.; Frensing, T.; Reichl, U.: Single-Cell Analysis of Influenza A Virus-Infected Cells. 26th Annual Meeting of the Society for Virology, Münster, Germany (2016)
Talk
Kupke, S. Y.; Heldt, S.; Frensing, T.; Reichl, U.: Heterogeneity in Influenza A Virus Infection Unveiled by Single-Cell Analysis and Stochastic Mathemeatical Modeling. Single Cell Technologies 2016, Frankfurt/Main (2016)
Talk
Kupke, S. Y.; Heldt, S.; Frensing, T.; Reichl, U.: Single-Cell Analysis of Influenza A Virus-Infected Cells for the Optimization of Cell Culture-Based Vaccine Production. Vaccine Technology VI, Albufeira, Portugal (2016)

Poster (6)

2020
Poster
Kupke, S. Y.; Hein, M. D.; Kollmus, H.; Marichal-Gallardo, P.; Schughart, K.; Reichl, U.: The novel influenza A virus defective interfering particle "OP7" as an antiviral agent: discovery, production, and animal trials. The seventh ESWI Influenza Conference, Virtual Meeting (2020)
2019
Poster
Kupke, S. Y.; Riedel, D.; Frensing, T.; Zmora, P.; Reichl, U.: A novel type of defective interfering particle for antiviral therapy. 26th ESACT Meeting, Copenhagen, Denmark (2019)
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