Publications

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Journal Article (4)

  1. Journal Article
    Rüdiger, D.; Kupke, S. Y.; Laske, T.; Zmora, P.; Reichl, U.: Multiscale modeling of influenza A virus replication in cell cultures predicts infection dynamics for highly different infection conditions. PLoS Computational Biology 15 (2), e1006819 (2019)
  2. Journal Article
    Laske, T.; Heldt, S.; Hoffmann, H.; Frensing, T.; Reichl, U.: Reprint of “Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs. Virus Research 218, pp. 86 - 95 (2016)
  3. Journal Article
    Castro, R.; Fernandes, P.; Laske, T.; Sousa, M. F. Q.; Genzel, Y.; Scharfenberg, K.; Alves, P.M.; Coroadinha, A.S.: Production of canine adenovirus type 2 in serum-free suspension cultures of MDCK cells. Applied Microbiology and Biotechnology 99 (17), pp. 7059 - 7068 (2015)
  4. Journal Article
    Peschel, B.; Frentzel, S.; Laske, T.; Genzel, Y.; Reichl, U.: Comparison of influenza virus yields and apoptosis-induction in an adherent and a suspension MDCK cell line. Vaccine 31 (48), pp. 5693 - 5699 (2013)

Conference Paper (2)

  1. Conference Paper
    Duvigneau, S.; Dürr, R.; Laske, T.; Bachmann, M.; Dostert, M.; Reichl, U.; Kienle, A.: Mathematical modeling as a tool to improve influenza vaccine production processes. FOSBE 2018, Chicago, Illinois, USA, August 05, 2018 - August 08, 2018. IFAC-PapersOnLine 51 (19), pp. 1 - 4 (2018)
  2. Conference Paper
    Dürr, R.; Duvigneau, S.; Laske, T.; Bachmann, M.; Kienle, A.: Analyzing the Impact of Heterogeneity in Genetically Engineered Cell Lines for Influenza Vaccine Production Using Population Balance Modeling. Foundations of Systems Biology in Engineering - FOSBE 2016 — Magdeburg, Germany, 9—12 October 2016, Magdeburg, Germany, October 09, 2016 - October 12, 2016. IFAC-PapersOnLine 49 (26), pp. 225 - 230 (2016)

Meeting Abstract (1)

  1. Meeting Abstract
    Fernandes, P.; Castro, R.; Laske, T.; Genzel, Y.; Kremer, E.; Alves, P.; Coroadinha, A.: The impact of MDCK cell source on the production of influenza and canine adenovirus. In New Biotechnology: Abstracts of the 16th European Congress on Biotechnology, 31 Supplement, p. S180. (2014)

Talk (4)

  1. Talk
    Laske, T.; Bachmann, M.; Dostert, M.; Karlas, A.; Wirth, D.; Frensing, T.; Reichl, U.: Model-based characterization of influenza A virus production in genetically engineered cell lines elucidates changes in virus replication. 3rd Workshop on Virus Dynamics, Heidelberg, Germany (2017)
  2. Talk
    Laske, T.; Bachmann, M.; Frensing, T.; Reichl, U.: Model-based analysis of influenza A virus replication in genetically modified cell lines elucidates virus-host cell interactions. 1st ESACT Frontiers Retreat, Lyon, France (2016)
  3. Talk
    Laske, T.; Heldt, F. S.; Frensing, T.; Reichl, U.: Analyzing the dynamics of influenza A virus replication in the presence of defective interfering RNAs. 2nd Workshop on Virus Dynamics, Toronto, Ontario, Canada (2015)
  4. Talk
    Laske, T.: Mathematical modeling of virus-host cell interactions during influenza virus replication supports cell line development for vaccine production. Workshop on Virus Dynamics and Evolution des Centre De Recerca Matemàtica (CRM), Bellaterra, Spain (2014)

Poster (7)

  1. Poster
    Laske, T.; Bachmann, M.; Dostert, M.; Frensing, T.; Karlas, A.; Wirth, D.; Reichl, U.: Modeling reveals changes in key parameters of infuenza A virus replication in engineered cell lines. 11th Annual International Conference on Systems Biology of Human Diseases, Los Angeles, USA (2018)
  2. Poster
    Dürr, R.; Duvigneau, S.; Laske, T.; Bachmann, M.; Kienle, A.: Analyzing the impact of heterogeneity in genetically engineered cell lines for influenza vaccine production using population balance modeling. 6th IFAC Conference on Foundations of Systems Biology in Engineering (FOSBE), Magdeburg, Germany (2016)
  3. Poster
    Laske, T.; Bachmann, M.; Frensing, T.; Reichl, U.: Model-based analysis of influenza A virus replication in genetically modified cell lines elucidates virus-host cell interactions. 17th International Conference on Systems Biology (ICSB), Barcelona, Spain (2016)
  4. Poster
    Laske, T.; Heldt, F. S.; Hoffmann, H.; Frensing, T.; Reichl, U.: Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs. 26th Annual Meeting of the Society for Virology, Münster, Germany (2016)
  5. Poster
    Laske, T.; Heldt, F. S.; Frensing, T.; Reichl, U.: Analyzing the intracellular replication of influenza A virus in the presence of defective interfering RNAs. International Conference on Systems Biology of Human Disease (SBHD), Heidelberg, Germany (2015)
  6. Poster
    Fernandes, P.; Castro, R.; Laske, T.; Genzel, Y.; Kremer, E.J.; Alves, P.M.; Coroadinha, A.S.: The impact of MDCK cell source on the production of Influenza and Canine Adenovirus. ECB16 - 16th European Congress on Biotechnology, Edinburgh, Scotland (2014)
  7. Poster
    Laske, T.; Heldt, S.; Frensing, T.; Reichl, U.: Mathematical modeling of virus-host cell interactions during influenza A virus replication supports cell line development for vaccine production. 4th International Influenza Meeting, Münster, Germany (2014)

Thesis - Master (1)

  1. Thesis - Master
    Laske, T.: Characterization of adherent and suspension MDCK cells as substrate for canine adenovirus type 2 production. Master, 71 pp., Otto-von-Guericke-Universität, Magdeburg (2013)

Thesis - Bachelor (1)

  1. Thesis - Bachelor
    Laske, T.: Durchflusszytometrische Untersuchung von Influenza-Infektionen an verschiedenen MDCK Zelllinien. Bachelor, 86 pp., Otto-von-Guericke-Universität, Mageburg (2011)
 
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