Publications of Pavel Marichal-Gallardo

Journal Article (9)

2021
Journal Article
Bissinger, T.; Wu, Y.; Marichal-Gallardo, P.; Riedel, D.; Liu, X.; Genzel, Y.; Tan, W.; Reichl, U.: Towards integrated production of an influenza A vaccine candidate with MDCK suspension cells. Biotechnology and Bioengineering 118 (10), pp. 3996 - 4013 (2021)
Journal Article
Gränicher, G.; Babakhani, M.; Göbel, S.; Jordan, I.; Marichal-Gallardo, P.; Genzel, Y.; Reichl, U.: A high cell density perfusion process for Modified Vaccinia virus Ankara production: process integration with inline DNA digestion and cost analysis. Biotechnology and Bioengineering 118 (12), pp. 4720 - 4734 (2021)
Journal Article
Hein, M. D.; Arora, P.; Marichal-Gallardo, P.; Winkler, M.; Genzel, Y.; Pöhlmann, S.; Schughart, K.; Kupke, S. Y.; Reichl, U.: Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles. BMC Biology 19 (1), 91 (2021)
Journal Article
Hein, M. D.; Kollmus, H.; Marichal-Gallardo, P.; Püttker, S.; Benndorf, D.; Genzel, Y.; Schughart, K.; Kupke, S. Y.; Reichl, U.: OP7, a novel influenza A virus defective interfering particle: production, purification, and animal experiments demonstrating antiviral potential. Applied Microbiology and Biotechnology 105, pp. 129 - 146 (2021)
Journal Article
Mahour, R.; Marichal-Gallardo, P.; Rexer, T.; Reichl, U.: Multi-enzyme cascades for the in vitro synthesis of guanosine diphosphate L-fucose. ChemCatChem 13 (8), pp. 1981 - 1989 (2021)
Journal Article
Marichal-Gallardo, P.; Börner, K.; Pieler, M.; Sonntag-Buck, V.; Obr, M.; Bejarano, D.; Wolff, M. W.; Kräusslich, H.-G.; Reichl, U.; Grimm, D.: Single-use capture purification of adeno-associated viral gene transfer vectors by membrane-based steric exclusion chromatography. Human Gene Therapy 32 (17-18), pp. 959 - 974 (2021)
Journal Article
Rand, U.; Kupke, S. Y.; Shkarlet, H.; Hein, M. D.; Hirsch, T.; Marichal-Gallardo, P.; Cicin-Sain, L.; Reichl, U.; Bruder, D.: Antiviral Activity of Influenza A Virus Defective Interfering Particles against SARS-CoV-2 Replication In Vitro through Stimulation of Innate Immunity. Cells 10 (7), 1756 (2021)
2019
Journal Article
Gränicher, G.; Coronel, J.; Pralow, A.; Marichal-Gallardo, P.; Wolff, M. W.; Rapp, E.; Karlas, A.; Sandig, V.; Genzel, Y.; Reichl, U.: Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG.PK2.1. Vaccine 37 (47), pp. 7019 - 7028 (2019)
2017
Journal Article
Marichal-Gallardo, P.; Pieler, M.; Wolff, M. W.; Reichl, U.: Steric exclusion chromatography for purification of cell culture-derived influenza A virus using regenerated cellulose membranes and polyethylene glycol. Journal of Chromatography A 1483 (3), pp. 110 - 119 (2017)

Meeting Abstract (2)

2019
Meeting Abstract
Marichal-Gallardo, P.; Genzel, Y.; Börner, K.; Grimm, D.; Wolff, M. W.; Reichl, U.: A single-use chromatographic purification platform for viral gene transfer vectors & viral vaccines. In Proceedings Advancing Manufacture of Cell and Gene Therapies VI, 92. Advancing Manufacture of Cell and Gene Therapies VI, Loews Coronado Bay Hotel Coronado, California, USA, January 27, 2019 - January 31, 2019. (2019)
2018
Meeting Abstract
Marichal-Gallardo, P.; Fortuna, A. R.; Genzel, Y.; Wolff, M. W.; Reichl, U.: Purifying viruses with a sheet of paper: Single-use steric exclusion chromatography as a capture platform for vaccine candidates. In Vaccine Technology VII, 128. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)

Talk (6)

2019
Talk
Marichal-Gallardo, P.; Genzel, Y.; Börner, K.; Grimm, D.; Wolff, M.W.; Reichl, U.: A single-use chromatographic purification platform for viral gene transfer vectors & viral vaccines. ECI Advancing Manufacture of Cell and Gene Therapies VI, Coronado, United States of America (2019)
Talk
Nikolay, A.; Tapia, F.; Marichal-Gallardo, P.; Pralow, A.; Hoffmann, M.; Rapp, E.; Genzel, Y.; Reichl, U.: Moderne Methoden der Impfstoffherstellung. Wissenschaft im Rathaus, Magdeburg, Germany (2019)
Talk
Nikolay, A.; Tapia, F.; Marichal-Gallardo, P.; Pralow, A.; Hoffmann, M.; Rapp, E.; Genzel, Y.; Reichl, U.: Cell Culture-based Viral Vaccines: Process Intensification and Monitoring. Cuba Symposium “Frontiers of Science”, Havanna, Cuba (2019)
Talk
Tapia, F.; Marichal-Gallardo, P.; Reichl, U.: A universal platform for continuous manufacturing of viral vaccines & gene therapy vectors. Workshop Bioverfahrenstechnik, Leuna, Germany (2019)
2018
Talk
Marichal-Gallardo, P.; Genzel, Y.; Börner, K.; Grimm, D.; Wolff, M. W.; Reichl, U.: A single-use purification platform for viral vaccines & gene therapy vectors. International Symposium on the Separation of Proteins, Peptides, and Polynucleotides (ISPPP) 2018, Berlin, Germany (2018)
Talk
Marichal-Gallardo, P.; Lothert, K.; Grein, T.; Reichl, U.; Czermak, P.; Wolff, M. W.: Single-use purification of cell culture-based virus particles by steric exclusion chromatography. National Meeting of the American Chemical Society (ACS), New Orleans, USA (2018)

Poster (2)

2020
Poster
Kupke, S. Y.; Hein, M. D.; Kollmus, H.; Marichal-Gallardo, P.; Schughart, K.; Reichl, U.: The novel influenza A virus defective interfering particle "OP7" as an antiviral agent: discovery, production, and animal trials. The seventh ESWI Influenza Conference, Virtual Meeting (2020)
2018
Poster
Wolff, M. W.; Marichal-Gallardo, P.; Lothert, K.; Riedel, D.; Börner, K.; Fortuna, A. R.; Czermak, P.; Reichl, U.: A step towards globally affordable vaccines & gene therapies: Steric exclusion chromatography as a capture platform. Recovery of Biological Products, Asheville, USA (2018)

Thesis - PhD (1)

2019
Thesis - PhD
Marichal-Gallardo, P.: Chromatographic purification of biological macromolecules by their capture on hydrophilic surfaces with the aid of non-ionic polymers. Dissertation, Otto-von-Guericke-Universität, Magdeburg (2019)
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