Publications BPE group

Journal Article (40)

2021
Journal Article
Bartholomäus, A.; Kolte, B.; Mustafayeva, A.; Goebel, I.; Fuchs, S.; Benndorf, D.; Engelmann, S.; Ignatova, Z.: smORFer: a modular algorithm to detect small ORFs in prokaryotes. Nucleic Acids Research (London) 49 (15), e89 (2021)
Journal Article
Bastida, F.; Jehmlich, N.; Starke, R.; Schallert, K.; Benndorf, D.; López-Mondéjar, R.; Plaza, C.; Freixino, Z.; Ramírez-Ortuño, C.; Ruiz-Navarro, A. et al.; Díaz-López, M.; Vera, A.; Moreno, J.L.; Eldridge, D.J.; García, C.; Delgado-Baquerizo, M.: Structure and function of bacterial metaproteomes across biomes. Soil Biology and Biochemistry 160, 108331 (2021)
Journal Article
Biemann, R.; Buß, E.; Benndorf, D.; Lehmann, T.; Schallert, K.; Püttker, S.; Reichl, U.; Isermann, B.; Schneider, J. G.; Saake, G. et al.; Heyer, R.: Fecal Metaproteomics Reveals Reduced Gut Inflammation and Changed Microbial Metabolism Following Lifestyle-Induced Weight Loss. Biomolecules 11 (5), 726 (2021)
Journal Article
Bissinger, T.; Wu, Y.; Marichal-Gallardo, P.; Riedel, D.; Liu, X.; Genzel, Y.; Tan, W.; Reichl, U.: Towards integrated production of an influenza A vaccine candidate with MDCK suspension cells. Biotechnology and Bioengineering 118 (10), pp. 3996 - 4013 (2021)
Journal Article
Chuzel, L.; Fossa, S. L.; Boisvert, M. L.; Cajic, S.; Hennig, R.; Ganatra, M. B.; Reichl, U.; Rapp, E.; Taron, C. H.: Combining functional metagenomics and glycoanalytics to identify enzymes that facilitate structural characterization of sulfated N-glycans. Microbial Cell Factories 20 (20), 162 (2021)
Journal Article
De Vrieze, J.; Heyer, R.; Props, R.; Van Meulebroek, L.; Gille, K.; Vanhaecke, L.; Benndorf, D.; Boon, N.: Triangulation of microbial fingerprinting in anaerobic digestion reveals consistent fingerprinting profiles. Water Research 202 (1), 117422 (2021)
Journal Article
Di Marco, F.; Berger, T.; Esser-Skala, W.; Rapp, E.; Regl, C.; Huber, C. G.: Simultaneous Monitoring of Monoclonal Antibody Variants by Strong Cation-Exchange Chromatography Hyphenated to Mass Spectrometry to Assess Quality Attributes of Rituximab-Based Biotherapeutics. International Journal of Molecular Sciences 22 (16), 9072 (2021)
Journal Article
Eussen, S. R. B. M.; Mank, M.; Kottler, R.; Hoffmann, X.-K.; Behne, A.; Rapp, E.; Stahl, B.; Mearin, M. L.; Koletzko, B.: Presence and Levels of Galactosyllactoses and Other Oligosaccharides in Human Milk and Their Variation during Lactation and According to Maternal Phenotype. Nutrients 13 (7), 2324 (2021)
Journal Article
Feichtinger, R. G.; Hüllen, A.; Koller, A.; Kotzot, D.; Grote, V.; Rapp, E.; Hofbauer, P.; Brugger, K.; Thiel, C.; Mayr, J. A. et al.; Wortmann, S. B.: A spoonful of L‐fucose—an efficient therapy for GFUS‐CDG, a new glycosylation disorder. Embo Molecular Medicine 13 (9), e14332 (2021)
Journal Article
Fortuna, A. R.; Taft, F.; Villain, L.; Wolff, M. W.; Reichl, U.: Continuous purification of influenza A virus particles using pseudo-affinity membrane chromatography. Journal of Biotechnology 342, pp. 139 - 148 (2021)
Journal Article
Gränicher, G.; Babakhani, M.; Göbel, S.; Jordan, I.; Marichal-Gallardo, P.; Genzel, Y.; Reichl, U.: A high cell density perfusion process for Modified Vaccinia virus Ankara production: process integration with inline DNA digestion and cost analysis. Biotechnology and Bioengineering 118 (12), pp. 4720 - 4734 (2021)
Journal Article
Gränicher, G.; Tapia, F.; Behrendt, I.; Jordan, I.; Genzel, Y.; Reichl, U.: Production of Modified Vaccinia Ankara Virus by Intensified Cell Cultures: A Comparison of Platform Technologies for Viral Vector Production. Biotechnology Journal 16 (1), e2000024 (2021)
Journal Article
Gücüm, S.; Sakson, R.; Hoffmann, M.; Grote, V.; Becker, C.; Pakari, K.; Beedgen, L.; Thiel, C.; Rapp, E.; Ruppert, T. et al.; Thumberger, T.; Wittbrodt, J.: A patient-based medaka alg2 mutant as a model for hypo-N-glycosylation. Development 148 (11), dev199385 (2021)
Journal Article
Hassa, J.; Klang, J.; Benndorf, D.; Pohl, M.; Hülsemann, B.; Mächtig, T.; Effenberger, M.; Pühler, A.; Schlüter, A.; Theuerl, S.: Indicative Marker Microbiome Structures Deduced from the Taxonomic Inventory of 67 Full-Scale Anaerobic Digesters of 49 Agricultural Biogas Plants. Microorganisms 9 (7), 1457 (2021)
Journal Article
Hein, M. D.; Arora, P.; Marichal-Gallardo, P.; Winkler, M.; Genzel, Y.; Pöhlmann, S.; Schughart, K.; Kupke, S. Y.; Reichl, U.: Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles. BMC Biology 19 (1), 91 (2021)
Journal Article
Hein, M. D.; Chawla, A.; Cattaneo, M.; Kupke, S. Y.; Genzel, Y.; Reichl, U.: Cell culture–based production of defective interfering influenza A virus particles in perfusion mode using an alternating tangential flow filtration system. Applied Microbiology and Biotechnology 105, pp. 7251 - 7264 (2021)
Journal Article
Hein, M. D.; Kollmus, H.; Marichal-Gallardo, P.; Püttker, S.; Benndorf, D.; Genzel, Y.; Schughart, K.; Kupke, S. Y.; Reichl, U.: OP7, a novel influenza A virus defective interfering particle: production, purification, and animal experiments demonstrating antiviral potential. Applied Microbiology and Biotechnology 105 (1), pp. 129 - 146 (2021)
Journal Article
Kawahara, R.; Chernykh, A.; Alagesan, K.; Bern, M.; Cao, W.; Chalkley, R. J.; Cheng, K.; Choo, M. S.; Edwards, N.; Goldman, R. et al.; Hoffmann, M.; Hu, Y.; Huang, Y.; Kim, J. Y.; Kletter, D.; Liquet, B.; Liu, M.; Mechref, Y.; Meng, B.; Neelamegham, S.; Nguyen-Khuong, T.; Nilsson, J.; Pap, A.; Park, G. W.; Parker, B. L.; Pegg, C. L.; Penninger, J. M.; Phung, T. K.; Pioch, M.; Rapp, E.; Sakalli, E.; Sanda, M.; Schulz, B. L.; Scott, N. E.; Sofronov, G.; Stadlmann, J.; Vakhrushev, S. Y.; Woo, C. M.; Wu, H.-Y.; Yang, P.; Ying, W.; Zhang, H.; Zhang, Y.; Zhao, J.; Zaia, J.; Haslam, S. M.; Palmisano, G.; Yoo, J. S.; Larson, G.; Khoo, K.-H.; Medzihradszky, K. F.; Kolarich, D.; Packer, N. H.; Thaysen-Andersen, M.: Community evaluation of glycoproteomics informatics solutions reveals high-performance search strategies for serum glycopeptide analysis. Nature Methods 18, pp. 1304 - 1316 (2021)
Journal Article
Lebede, M.; Di Marco, F.; Esser-Skala, W.; Hennig, R.; Wohlschlager, T.; Huber, C. G.: Exploring the Chemical Space of Protein Glycosylation in Noncovalent Protein Complexes: An Expedition along Different Structural Levels of Human Chorionic Gonadotropin by Employing Mass Spectrometry. Analytical Chemistry 93, pp. 10424 - 10434 (2021)
Journal Article
Litschko, C.; Budde, I.; Berger, M.; Bethe, A.; Schulze, J.; Alcala Orozco, E. A.; Mahour, R.; Goettig, P.; Führing, J. I.; Rexer, T. et al.; Gerardy-Schahn, R.; Schubert, M.; Fiebig, T.: Mix-and-Match System for the Enzymatic Synthesis of Enantiopure Glycerol-3-Phosphate-Containing Capsule Polymer Backbones from Actinobacillus pleuropneumoniae, Neisseria meningitidis, and Bibersteinia trehalosi. mBio 12 (3), e00897-21 (2021)
Journal Article
Mahour, R.; Marichal-Gallardo, P.; Rexer, T.; Reichl, U.: Multi-enzyme cascades for the in vitro synthesis of guanosine diphosphate L-fucose. ChemCatChem 13 (8), pp. 1981 - 1989 (2021)
Journal Article
Marichal-Gallardo, P.; Börner, K.; Pieler, M.; Sonntag-Buck, V.; Obr, M.; Bejarano, D.; Wolff, M. W.; Kräusslich, H.-G.; Reichl, U.; Grimm, D.: Single-use capture purification of adeno-associated viral gene transfer vectors by membrane-based steric exclusion chromatography. Human Gene Therapy 32 (17-18), pp. 959 - 974 (2021)
Journal Article
Meinusch, N.; Kramer, S.; Körner, O.; Wiese, J.; Seick, I.; Beblek, A.; Berges, R.; Illenberger, B.; Illenberger, M.; Uebbing, J. et al.; Wolf, M.; Saake, G.; Benndorf, D.; Reichl, U.; Heyer, R.: Integrated Cycles for Urban Biomass as a Strategy to Promote a CO2-Neutral Society—A Feasibility Study. Sustainability 13 (17), 9505 (2021)
Journal Article
Noor, S. I.; Hoffmann, M.; Rinis, N.; Bartels, M. F.; Winterhalter, P. R.; Hoelscher, C.; Hennig, R.; Himmelreich, N.; Thiel, C.; Ruppert, T. et al.; Rapp, E.; Strahl, S.: Glycosyltransferase POMGNT1 deficiency strengthens N-cadherin-mediated cell-cell adhesion. Journal of Biological Chemistry, 100433 (2021)
Journal Article
Offersgaard, A.; Duarte Hernandez, C. R.; Pihl, A. F.; Costa, R.; Venkatesan, N. P.; Lin, X.; Van Pham, L.; Feng, S.; Fahnøe, U.; Scheel, T. K. H. et al.; Ramirez, S.; Reichl, U.; Bukh, J.; Genzel, Y.; Gottwein, J. M.: SARS-CoV-2 Production in a Scalable High Cell Density Bioreactor. Vaccines 9 (7), 706 (2021)
Journal Article
Patenaude, A.; Erhardt, J.; Hennig, R.; Rapp, E.; Lauc, G.; Pezer, M.: N‐glycosylation analysis of mouse immunoglobulin G isolated from dried blood spots. Electrophoresis: Special Issue: Monoliths 2021 42 (24), pp. 2615 - 2618 (2021)
Journal Article
Pech, S.; Rehberg, M.; Janke, R.; Benndorf, D.; Genzel, Y.; Muth, T.; Sickmann, A.; Rapp, E.; Reichl, U.: Tracking changes in adaptation to suspension growth for MDCK cells: cell growth correlates with levels of metabolites, enzymes and proteins. Applied Microbiology and Biotechnology 105 (5), pp. 1861 - 1874 (2021)
Journal Article
Pelz, L.; Rüdiger, D.; Dogra, T.; Alnaji, F. G.; Genzel, Y.; Brooke, C. B.; Kupke, S. Y.; Reichl, U.: Semi-continuous propagation of influenza A virus and its defective interfering particles: analyzing the dynamic competition to select candidates for antiviral therapy. Journal of Virology 95 (24), e01174-21 (2021)
Journal Article
Pralow, A.; Hoffmann, M.; Nguyen-Khuong, T.; Pioch, M.; Hennig, R.; Genzel, Y.; Rapp, E.; Reichl, U.: Comprehensive N‐glycosylation analysis of the influenza A virus proteins HA and NA from adherent and suspension MDCK cells. The FEBS Journal 288 (16), pp. 4869 - 4891 (2021)
Journal Article
Pralow, A.; Nikolay, A.; Leon, A.; Genzel, Y.; Rapp, E.; Reichl, U.: Site-specific N-glycosylation analysis of animal cell culture-derived Zika virus proteins. Scientific Reports 11 (1), 5147 (2021)
Journal Article
Puan, K. J.; San Luis, B.; Yusof, N.; Kumar, D.; Andiappan, A. K.; Lee, W.; Cajic, S.; Vuckovic, D.; Chan, J. D.; Döllner, T. et al.; Hou, H. W.; Jiang, Y.; Tian, C.; Agee, M.; Aslibekyan, S.; Auton, A.; Babalola, E.; Bell, R. K.; Bielenberg, J.; Bryc, K.; Bullis, E.; Cameron, B.; Coker, D.; Partida, G. C.; Dhamija, D.; Das, S.; Elson, S. L.; Filshtein, T.; Fletez-Brant, K.; Fontanillas, P.; Freyman, W.; Gandhi, P. M.; Heilbron, K.; Hicks, B.; Hinds, D. A.; Huber, K. E.; Jewett, E. M.; Kleinman, A.; Kukar, K.; Lane, V.; Lin, K.-H.; Lowe, M.; Luff, M. K.; McCreight, J. C.; McIntyre, M. H.; McManus, K. F.; Micheletti, S. J.; Moreno, M. E.; Mountain, J. L.; Mozaffari, S. V.; Nandakumar, P.; Noblin, E. S.; O’Connell, J.; Petrakovitz, A. A.; Poznik, G. D.; Schumacher, M.; Shastri, A. J.; Shelton, J. F.; Shi, J.; Shringarpure, S.; Tran, V.; Tung, J. Y.; Wang, X.; Wang, W.; Weldon, C. H.; Wilton, P.; Rapp, E.; Poidinger, M.; Wang, D. Y.; Soranzo, N.; Lee, B.; Rötzschke, O.: FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x expression. Communications Biology 4, 832 (2021)
Journal Article
Rand, U.; Kupke, S. Y.; Shkarlet, H.; Hein, M. D.; Hirsch, T.; Marichal-Gallardo, P.; Cicin-Sain, L.; Reichl, U.; Bruder, D.: Antiviral Activity of Influenza A Virus Defective Interfering Particles against SARS-CoV-2 Replication In Vitro through Stimulation of Innate Immunity. Cells 10 (7), 1756 (2021)
Journal Article
Reichl, U.; Seidel-Morgenstern, A.; Sundmacher, K.; Tsotsas, E.; van Wachem, B.: Forschungsarbeiten am Institut für Verfahrenstechnik der Otto‐von‐Guericke‐Universität Magdeburg. Chemie Ingenieur Technik 93 (3), pp. 345 - 352 (2021)
Journal Article
Rüdiger, D.; Pelz, L.; Hein, M. D.; Kupke, S. Y.; Reichl, U.: Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culture. PLoS Computational Biology 17, e1009357 (2021)
Journal Article
Ruhnau, J.; Grote, V.; Juarez-Osorio, M.; Bruder, D.; Mahour, R.; Rapp, E.; Rexer, T.; Reichl, U.: Cell-Free Glycoengineering of the Recombinant SARS-CoV-2 Spike Glycoprotein. Frontiers in Bioengineering and Biotechnology 9, 699026 (2021)
Journal Article
Starke, R.; Siles, J. A.; Fernandes, M. L. P.; Schallert, K.; Benndorf, D.; Plaza, C.; Jehmlich, N.; Delgado-Baquerizo, M.; Bastida, F.: The structure and function of soil archaea across biomes. Journal of Proteomics 237, 104147 (2021)
Journal Article
Van Den Bossche, T.; Arntzen, M. Ø.; Becher, D.; Benndorf, D.; Eijsink, V. G. H.; Henry, C.; Jagtap, P. D.; Jehmlich, N.; Juste, C.; Kunath, B. J. et al.; Mesuere, B.; Muth, T.; Pope, P. B.; Seifert, J.; Tanca, A.; Uzzau, S.; Wilmes, P.; Hettich, R. L.; Armengaud, J.: The Metaproteomics Initiative: a coordinated approach for propelling the functional characterization of microbiomes. Microbiome 9 (1), 243 (2021)
Journal Article
Van Den Bossche, T.; Kunath, B. J.; Schallert, K.; Schäpe, S. S.; Abraham, P. E.; Armengaud, J.; Arntzen, M. Ø.; Bassignani, A.; Benndorf, D.; Fuchs, S. et al.; Giannone, R. J.; Griffin, T. J.; Hagen, L. H.; Halder, R.; Henry, C.; Hettich, R. L.; Heyer, R.; Jagtap, P.; Jehmlich, N.; Jensen, M.; Juste, C.; Kleiner, M.; Langella, O.; Lehmann, T.; Leith, E.; May, P.; Mesuere, B.; Miotello, G.; Peters, S. L.; Pible, O.; Reichl, U.; Renard, B. Y.; Schiebenhoefer, H.; Scryba, A.; Tanca, A.; Trappe, K.; Trezzi, J.-P.; Uzzau, S.; Verschaffelt, P.; von Bergen, M.; Wilmes, P.; Wolf, M.; Martens, L.; Muth, T.: Critical Assessment of Metaproteome Investigation (CAMPI): A Multi-Lab Comparison of Established Workflows. Nature Communications 12 (1), 7305 (2021)
Journal Article
Walke, D.; Schallert, K.; Ramesh, P.; Benndorf, D.; Lange, E.; Reichl, U.; Heyer, R.: MPA_Pathway_Tool: User-Friendly, Automatic Assignment of Microbial Community Data on Metabolic Pathways. International Journal of Molecular Sciences 22 (20), 10992 (2021)
Journal Article
Wu, Y.; Bissinger, T.; Genzel, Y.; Liu, X.; Reichl, U.; Tan, W.-S.: High cell density perfusion process for high yield of influenza A virus production using MDCK suspension cells. Applied Microbiology and Biotechnology 105 (4), pp. 1421 - 1434 (2021)

Book (1)

2021
Book
Rapp, E.; Reichl, U. (Eds.): Advances in Glycobiotechnology. Springer, Cham, Switzerland (2021), 463 pp.

Book Chapter (5)

2021
Book Chapter
Alagesan, K.; Hoffmann, M.; Rapp, E.; Kolarich, D.: Glycoproteomics Technologies in Glycobiotechnology. In: Advances in Glycobiotechnology, pp. 413 - 434 (Eds. Rapp, E.; Reichl, U.). Springer, Cham, Switzerland (2021)
Book Chapter
Butler, M.; Reichl, U.: Animal Cell Expression Systems. In: Advances in Glycobiotechnology, pp. 1 - 36 (Eds. Rapp, E.; Reichl, U.). Springer, Cham, Switzerland (2021)
Book Chapter
Cajic, S.; Hennig, R.; Burock, R.; Rapp, E.: Capillary (Gel) Electrophoresis-Based Methods for Immunoglobulin (G) Glycosylation Analysis. In: Antibody Glycosylation, pp. 137 - 172 (Ed. Pezer, M.). Springer, Cham, Switzerland (2021)
Book Chapter
Pralow, A.; Cajic, S.; Alagesan, K.; Kolarich, D.; Rapp, E.: State-of-the-Art Glycomics Technologies in Glycobiotechnology. In: Advances in Glycobiotechnology, pp. 379 - 411 (Eds. Rapp, E.; Reichl, U.). Springer, Cham, Switzerland (2021)
Book Chapter
Rexer, T.; Laaf, D.; Gottschalk, J.; Frohnmeyer, H.; Rapp, E.; Elling, L.: Enzymatic Synthesis of Glycans and Glycoconjugates. In: Advances in Glycobiotechnology, pp. 231 - 280 (Eds. Rapp, E.; Reichl, U.). Springer, Cham, Switzerland (2021)

Meeting Abstract (1)

2021
Meeting Abstract
Beimdiek, J.; Hennig, R.; Burock, R.; Puk, O.; Biskup, S.; Rapp, E.; Lesinski-Schiedat, A.; Buettner, F. F. R.; Das, A. M.: CDG-IIb syndrome: Clinical phenotype and in-depth glycomic characterization of a novel patient. In Glycobiology, 31 12 Ed., P145, p. 1745 - 1745. 2021 Annual Meeting of the Society for Glycobiology, San Diego, California, USA, November 07, 2021 - November 10, 2021. Oxford University Press, Oxford (2021)

Talk (9)

2021
Talk
Genzel, Y.: ESACT Course on Cell Culture-based Viral Vaccines (6th Edition):Cells, Upstream Processing and Process Intensification. ESACT Course 2021, Virtual Meeting (2021)
Talk
Genzel, Y.: ESACT Course on Cell Culture-based Viral Vaccines (6th Edition): Overview on COVID-19 candidate vaccines. ESACT Course 2021, Virtual Meeting (2021)
Talk
Genzel, Y.: ESACT Course on Cell Culture-based Viral Vaccines (6th Edition): Exercise on COVID-19 antigen design options and vaccination platforms. ESACT Course 2021, Virtual Meeting (2021)
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