Publications BPE group
Journal Article (16)
2012
Journal Article
7 (12), pp. 1522 - 1529 (2012)
How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology? Biotechnology Journal
Journal Article
58 (7), pp. 917 - 922 (2012)
Metaproteome analysis to determine the metabolically active part of thermophilic microbial community producing biogas from agricultural biomass. Canadian Journal of Microbiology
Journal Article
86 (15), pp. 7806 - 7817 (2012)
Modeling the intracellular dynamics of influenza virus replication to understand the control of viral RNA synthesis. Journal of Virology
Journal Article
30 (35), pp. 5253 - 5261 (2012)
Productivity, apoptosis, and infection dynamics of influenza A/PR/8 strains and A/PR/8-based reassortants. Vaccine
Journal Article
12 (12), pp. 1893 - 1901 (2012)
Proteomic tracking and analysis of a bacterial mixed culture. Proteomics
Journal Article
18 (41), pp. 12986 - 12998 (2012)
Red-Emitting Rhodamines with Hydroxylated, Sulfonated, and Phosphorylated Dye Residues and Their Use in Fluorescence Nanoscopy. Chemistry - A European Journal
Journal Article
12, 79 (2012)
Live attenuated influenza viruses produced in a suspension process with avian AGE1.CR.pIX cells. BMC Biotechnology
Journal Article
28 (4), pp. 584 - 586 (2012)
JDet: interactive calculation and visualization of function-related conservation patterns in multiple sequence alignments and structures. Bioinformatics
Journal Article
12 (5), pp. 518 - 528 (2012)
Evaluation of criteria for bioreactor comparison and operation standardization for mammalian cell culture. Engineering in Life Sciences
Journal Article
26 (2), pp. 2930 - 2936 (2012)
Effect of the 3’-terminal truncation of the human interferon-gamma gene on plasmid segregation in escherichia coli. Biotechnology and Biotechnological Equipment
Journal Article
46 (1), pp. 60 - 61 (2012)
Limonade durch Fermentation. Chemie in unserer Zeit
Journal Article
12 (2), pp. 188 - 197 (2012)
Time-kill studies with a ceftazidime-treated mixed culture consisting of Pseudomonas aeruginosa, Burkholderia cepacia and Staphylococcus aureus. Engineering in Life Sciences
Journal Article
81 A (12), pp. 1055 - 1066 (2012)
A Flow Cytometric Method for Viability Assessment of Staphylococcus aureus and Burkholderia cepacia in Mixed Culture. Cytometry Part A
Journal Article
93 (2), pp. 601 - 611 (2012)
Trypsin promotes efficient influenza vaccine production in MDCK cells by interfering with the antiviral host response. Applied Microbiology and Biotechnology
Journal Article
12 (9), pp. 1337 - 1348 (2012)
MALDI-TOF-MS analysis of sialylated glycans and glycopeptides using 4-chloro-α-cyanocinnamic acid matrix. Proteomics
Journal Article
11 (12), pp. 5804 - 5814 (2012)
Glycoproteomic Analysis of Human Fibrinogen Reveals Novel Regions of O‑Glycosylation. Journal of Proteome Research Conference Paper (7)
2012
Conference Paper
45 (2), pp. 320 - 325 (2012)
Distributed Modeling and Parameter Estimation of Influenza Virus Replication During Vaccine Production. MATHMOD 2012 - 7th Vienna International Conference on Mathematical Modelling, Vienna, Austria, February 15, 2012 - February 17, 2012. IFAC Proceedings Volumes
Conference Paper
Monitoring of Host-Cell Infection and Virus-Induced Apoptosis in Influenza Vaccine Production. In: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), pp. 675 - 683 (Eds. Jenkins, N.; Barron, N.; Alves, P.). 21st ESACT Meeting , Dublin, Ireland, June 07, 2009 - June 10, 2009. (2012)
Conference Paper
Accounting for the Entire Influenza Hemagglutinin during a Flu Vaccine Production Process. In: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), pp. 685 - 689. 21st ESACT Meeting , Dublin, Ireland, June 07, 2009 - June 10, 2009. Berlin (2012)
Conference Paper
Avian Designer Cells AGE1.CR as Candidates for MVA and Influenza Vaccine Production. In: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), pp. 615 - 631 (Eds. Jenkins, N.; Barron, N.; Alves, P.). 21st ESACT Meeting, Dublin, Ireland, June 07, 2009 - June 10, 2009. (2012)
Conference Paper
Flow characterization in wave bioreactors using Computational Fluid Dynamics. In: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), pp. 455 - 469 (Eds. Jenkins, N.; Barron, N.; Alves, P.). 21st ESACT Meeting, Dublin, Ireland, June 07, 2009 - June 10, 2009. Dordrecht (2012)
Conference Paper
Optimized CGE-LIF-based glycan analysis for high-throughput applications. In: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), pp. 599 - 603 (Eds. Jenkins, N.; Barron, N.; Alves, P.). 21st ESACT Meeting, Dublin, Ireland, June 07, 2009 - June 10, 2009. (2012)
Conference Paper
45 (2), pp. 165 - 170 (2012)
Parameter Identification of Time-Delay Systems: A Flatness Based Approach. MATHMOD 2012 - 7th Vienna International Conference on Mathematical Modelling, Vienna, Austria, February 15, 2012 - February 17, 2012. IFAC Proceedings Volumes Talk (16)
2012
Talk
Distributed Modeling and Parameter Estimation of Influenza Virus Replication During Vaccine Production. MATHMOD 2012 - 7th Vienna International Conference on Mathematical Modelling, Vienna, Austria (2012)
Talk
Cell culture-based influenza virus production: suspension or adherent producer cell lines? Cell line development and engineering 2012, Cologne, Germany (2012)
Talk
High cell density cultivations for influenza virus production using suspension cells. Vaccine Technology IV, Albufeira, Portugal (2012)
Talk
Elucidating bottlenecks in influenza virus replication to optimize vaccine production. International Conference on the Systems Biology of Human Disease, Heidelberg, Germany (2012)
Talk
Tailored sample preparation methods for xCGE-LIF based carbohydrate analysis. 23rd Joint Glycobiology Meeting 2012, Wageningen, The Netherlands (2012)
Talk
A high-throughput assay to assess enzyme activity in central metabolism of production cell lines. Cell Culture Engineering XIII, Scottsdale, Arizona, USA (2012)
Talk
Screening for hydrophobic interaction chromatography conditions for downstreaming of influenza virus. ACHEMA 2012, Frankfurt am Main, Germany (2012)
Talk
Proteomanalyse der Virus-Wirtszell-Interaktion: Tollwutvirus-Replikation in einer Vero Zelllinie unter Einfluss zweier Zellkulturmedien. Biopharmazeutische Produktion 2012, Freiburg (2012)
Talk
Dynamics of influenza A virsu transcription & replication in mammalian cell culture. 22nd Annual Meeting of the Society for Virology, Essen, Germany (2012)
Talk
Insights into mammalian energy metabolism: connecting intracellular metabolites and maximum enzyme activities. GVC/DECHEMA Vortrags- und Diskussionstagung - Biopharmazeutische Produktion, Freiburg (2012)
Talk
Cell Culture-derived Influenza Vaccine Production. Sächsische Akademie der Wisenschaften: Sitzung der Technikwissenschaftlichen Klasse, Leipzig (2012)
Talk
Process Conditions can markedly affect the N-glycosylation pattern and immunogenicity of influenza A virus. ACTIP Meeting, Marburg (2012)
Talk
Impact of process conditions on influenza A virus HA N-glycosylation and immunogenicity. ProcessNet-Jahrestagung und 30. DECHEMA-Jahrestagung der Biotechnologen, Karlsruhe (2012)
Talk
Charakterisierung medizinisch-relevanter bakterieller Mischkulturen mittels t-RFLP und Durchflusszytometrie. ProcessNet Jahrestagung 2012 und 30. Jahrestagung der Biotechnologen, Karlsruhe, Germany (2012)
Talk
Viability analysis of Lactobacillus plantarum by flow cytometry. ACHEMA 2012 Congress, Frankfurt, Germany (2012)
Talk
Downstream Processing of Cell Culture-derived Virus Particles. ProcessNet-Membranverfahren in der Biotechnologie, Frankfurt am Main, Germany (2012)
Poster (16)
2012
Poster
Modeling influenza virus replication on a single cell level. 3rd International Influenza Meeting, Muenster, Germany (2012)
Poster
Metabolic Flux Analysis of AAT Production in AGE1.HN.AAT Cells under Different Cultivation Conditions. ESBES - 9 th European Symposium on Biochemical Engineering Science, Istanbul (2012)
Poster
Comparison of the productivity of a new human cell line in different steady states of continuous cultivations using MFA. Metabolic Engineering IX, Biarritz, France (2012)
Poster
Elucidating bottlenecks in influenza virus replication to optimize vaccine production. International Conference on the Systems Biology of Human Disease, Heidelberg, Germany (2012)
Poster
Elucidating the dynamics of influenza virus replication by mathematical modeling. 22nd Annual Meeting of the Society for Virology, Essen, Germany (2012)
Poster
Tailored sample preparation methods for xCGE-LIF based carbohydrate analysis. 23rd Joint Glycobiology Meeting 2012, Wageningen, The Netherlands (2012)
Poster
glyXtool – a software for automated high-throughput processing of xCGE-LIF based glycoanalysis data. 6th Glycan Forum, Berlin, Germany (2012)
Poster
Glycosylation matters: role of viral hemagglutinin N-glycosylation in immunogenicity. European Congress of Immunology, Glasgow, Scotland (2012)
Poster
In-Depth Characterization of the Human Milk Oligosaccharide Composition via xCGE-LIF, Utilizing a Multiplexing Capillary DNA Sequencer. 6th Glycan Forum, Berlin, Germany (2012)
Poster
Characterization of AGE1.CR.pIX high cell density cultivations for vaccinia virus production. GVC/DECHEMA Vortrags- und Diskussionstagung Biopharmazeutische Produktion, Freiburg, Germany (2012)
Poster
Live attenuated influenza virus production in batch high cell density cultivation of suspension AGE1.CR.pIX cells. Vaccine Technology IV, Albufeira, Portugal (2012)