Publications BPE group

Beimdiek, J.; Hennig, R.; Burock, R.; Puk, O.; Biskup, S.; Rapp, E.; Lesinski-Schiedat, A.; Buettner, F. F. R.; Das, A. M.: Serum N-glycomics of a novel CDG-IIb patient reveals aberrant IgG glycosylation. Glycobiology 32 (5), pp. 380 - 390 (2022)

Göbel, S.; Kortum, F.; Chavez, K. J.; Jordan, I.; Sandig, V.; Reichl, U.; Altomonte, J.; Genzel, Y.: Cell-line screening and process development for a fusogenic oncolytic virus in small-scale suspension cultures. Applied Microbiology and Biotechnology 106, pp. 4945 - 4961 (2022)

Hinterholzer, A.; Moises, J.; Regl, C.; Schwap, S.; Rapp, E.; Huber, C. G.; Schubert, M.: Unambiguous identification of α-Gal epitopes in intact monoclonal antibodies by NMR spectroscopy. mAbs 14 (1), 2132977 (2022)

Hütte, H. J.; Tiemann, B.; Shcherbakova, A.; Grote, V.; Hoffmann, M.; Povolo, L.; Lommel, M.; Strahl, S.; Vakhrushev, S. Y.; Rapp, E. et al.; Buettner, F. F. R.; Halim, A.; Imberty, A.; Bakker, H.: A Bacterial Mannose Binding Lectin as a Tool for the Enrichment of C- and O-Mannosylated Peptides. Analytical Chemistry 94 (20), pp. 7329 - 7338 (2022)

Khesali Aghtaei, H.; Püttker, S.; Maus, I.; Heyer, R.; Huang, L.; Sczyrba, A.; Reichl, U.; Benndorf, D.: Adaptation of a microbial community to demand-oriented biological methanation. Biotechnology for Biofuels and Bioproducts 15, 125 (2022)

Küchler, J.; Püttker, S.; Lahmann, P.; Genzel, Y.; Kupke, S. Y.; Benndorf, D.; Reichl, U.: Absolute quantification of viral proteins during single-round replication of MDCK suspension cells. Journal of Proteomics 259, 104544 (2022)

Kuil, T.; Yayo, J.; Pechan, J.; Küchler, J.; van Maris, A. J. A.: Ethanol tolerance of Clostridium thermocellum: the role of chaotropicity, temperature and pathway thermodynamics on growth and fermentative capacity. Microbial Cell Factories 21, 273 (2022)

Lageveen-Kammeijer, G. S. M.; Rapp, E.; Chang, D.; Rudd, P. M.; Kettner, C.; Zaia, J.: The minimum information required for a glycomics experiment (MIRAGE): reporting guidelines for capillary electrophoresis. Glycobiology 32 (7), pp. 580 - 587 (2022)

Mahour, R.; Lee, J. W.; Grimpe, P.; Boecker, S.; Grote, V.; Klamt, S.; Seidel-Morgenstern, A.; Rexer, T.; Reichl, U.: Cell‐free multi‐enzyme synthesis and purification of uridine diphosphate galactose. ChemBioChem 23 (2), e202100361 (2022)

Möckel, M.; Baldok, N.; Walles, T.; Hartig, R.; Müller, A. J.; Reichl, U.; Genzel, Y.; Walles, H.; Wiese-Rischke, C.: Human 3D Airway Tissue Models for Real-Time Microscopy: Visualizing Respiratory Virus Spreading. Cells 11 (22), 3634 (2022)

Offersgaard, A.; Duarte Hernandez, C. R.; Pihl, A. F.; Venkatesan, N. P.; Krarup, H.; Lin, X.; Reichl, U.; Bukh, J.; Genzel, Y.; Gottwein, J. M.: High-Titer Hepatitis C Virus Production in a Scalable Single-Use High Cell Density Bioreactor. Vaccines 10 (2), 249 (2022)

Rodrigues Correia Ramos, J.; Bissinger, T.; Genzel, Y.; Reichl, U.: Impact of Influenza A Virus Infection on Growth and Metabolism of Suspension MDCK Cells Using a Dynamic Model. Metabolites 12 (3), 239 (2022)

Schallert, K.; Verschaffelt, P.; Mesuere, B.; Benndorf, D.; Martens, L.; Van Den Bossche, T.: Pout2Prot: An Efficient Tool to Create Protein (Sub)groups from Percolator Output Files. Journal of Proteome Research 21 (4), pp. 1175 - 1180 (2022)

Scoma, A.; Khor, W.; Coma, M.; Heyer, R.; Props, R.; Bouts, T.; Benndorf, D.; Li, D.; Zhang, H.; Rabaey, K.: Lignocellulose Fermentation Products Generated by Giant Panda Gut Microbiomes Depend Ultimately on pH Rather than Portion of Bamboo: A Preliminary Study. Microorganisms 10 (5), 978 (2022)

Sydor, S.; Dandyk, C.; Schwerdt, J.; Manka, P.; Benndorf, D.; Lehmann, T.; Schallert, K.; Wolf, M.; Reichl, U.; Canbay, A. et al.; Bechmann, L. P.; Heyer, R.: Discovering Biomarkers for Non-Alcoholic Steatohepatitis Patients with and without Hepatocellular Carcinoma Using Fecal Metaproteomics. International Journal of Molecular Sciences 23 (16), 8841 (2022)

Tolonen, A. C.; Beauchemin, N.; Bayne, C.; Li, L.; Tan, J.; Lee, J.; Meehan, B. M.; Meisner, J.; Millet, Y.; LeBlanc, G. et al.; Kottler, R.; Rapp, E.; Murphy, C.; Turnbaugh, P. J.; von Maltzahn, G.; Liu, C. M.; van Hylckama Vlieg, J. E. T.: Synthetic glycans control gut microbiome structure and mitigate colitis in mice. Nature Communications 13 (1), 1244 (2022)

Espinel-Rios, S.; Huber, N.; Alcalá Orozco, E. A.; Morabito, B.; Rexer, T.; Reichl, U.; Klamt, S.; Findeisen, R.: Cell-free biosynthesis meets dynamic optimization and control: a fed-batch framework. 9th IFAC Conference on Foundations of Systems Biology in Engineering (FOSBE), Cambridge, MA, August 28, 2022 - August 31, 2022. IFAC-PapersOnLine 55 (23), pp. 92 - 97 (2022)

Bürgin, T.; Coronel, J.; Fiddeke, K.; Karlas, A.; Sandig, V.; Genzel, Y.; Reichl, U.; Anderlei, T.: Producing viruses in orbit: Current developments for orbital shaken viral vaccine manufacturing. In Proceedings Vaccine Technology VIII, 54. Vaccine Technology VIII, Sitges (Spain), June 12, 2022 - June 17, 2022. (2022)

Göbel, S.; Dorn, M.; Jaén Chavez, K.; Jordan, I.; Sandig, V.; Altomonte, J.; Genzel, Y.; Reichl, U.: Production of a fusogenic oncolytic rVSV-NDV virus in perfusion processes. In Proceedings Vaccine Technology VIII, 60. Vaccine Technology VIII, Sitges (Spain), June 12, 2022 - June 17, 2022. (2022)

Göbel, S.; Pelz, L.; Behrendt, I.; Prömmel, M.; Altomonte, J.; Anderlei, T.; Bürgin, T.; Genzel, Y.; Reichl, U.: Scale-Down of an Ortbital Shaken Bioreactor: High Cell Density Cultivation in Perfusion Mode and Virus production. In Proceedings Single-Use Technologies V: Building the Future, 40. Single-Use Technologies V: Building the Future, Marseille, France, March 20, 2022 - March 23, 2022. (2022)

Offersgaard, A.; Duarte Hernandez, C. R.; Pihl, A. F.; Costa, R.; Prabhakar Venkatesan, N.; Lin, X.; Van Pham, L.; Feng, S.; Fahnøe, U.; Høyer Scheel, T. K. et al.; Ramirez, S.; Reichl, U.; Bukh, J.; Genzel, Y.; Gottwein, J. M.: SARS-COV-2 production in a single-use scalable high cell density bioreactor. In Proceedings Single-Use Technologies V: Building the Future, 29. Single-Use Technologies V: Building the Future, Marseille, France, March 20, 2022 - March 23, 2022. (2022)

Zinnecker, T. M.; Behrendt, I.; Lau, M.; Hinkelmann, A.; Thiele, K.; Badri, N.; Araujo, D.; Genzel, Y.; Reichl, U.: Automated single-cell cloning in chemically defined medium for new suspension MDCK cell lines and scale-down of influenza A virus production into ambr^®15 microbioreactors. In Proceedings Vaccine Technology VIII, 55. Vaccine Technology VIII, Sitges (Spain), June 12, 2022 - June 17, 2022. (2022)

Göbel, S.; Pelz, L.; Behrendt, I.; Prömmel, M.; Altomonte, J.; Anderlei, T.; Bürgin, T.; Genzel, Y.; Reichl, U.: Scale-Down of an Ortbital Shaken Bioreactor: High Cell Density Cultivation in Perfusion Mode and Virus production. Single-Use Technologies V: Building the Future, Marseille, France (2022)

Gränicher, G.; Göbel, S.; Marichal-Gallardo, P.; Jordan, I.; Sandig, V.; Genzel, Y.; Reichl, U.: Integrated cell-culture based MVA virus production process with perfusion mode for vaccines or gene therapy. Value through intensified bioprocessing II, Oxford, United Kingdom (2022)

Gränicher, G.; Göbel, S.; Marichal-Gallardo, P.; Jordan, I.; Sandig, V.; Genzel, Y.; Reichl, U.: Integrated cell-culture based MVA virus production process with perfusion mode for vaccines or gene therapy. 27th ESACT Meeting, Lisbon (Portugal) (2022)

Hein, M.; Chawla, A.; Arora , P.; Cattaneo, M.; Winkler, M.; Pöhlmann, S.; Schughart, K.; Genzel, Y.; Kupke, S. Y.; Reichl, U.: Production of influenza A virus defective interfering particles in a high cell density perfusion cultivation with continuous virus harvesting. Vaccine Technology VIII, Sitges (Spain) (2022)

Hein, M.; Dogra, T.; Arora , P.; Rand , U.; Genzel, Y.; Cattaneo, M.; Winkler, M.; Cicin-Sain, L.; Bruder, D.; Schughart, K. et al.; Pöhlmann, S.; Kupke, S. Y.; Reichl, U.: Influenza A Virus-Derived Defective Interfering Particles for Antiviral Treatment. 27th ESACT Meeting, Lisbon (Portugal) (2022)

Huber, N.; Alcalá Orozco, E. A.; Rexer, T.; Reichl, U.; Klamt, S.: Dynamic Modeling and Optimization of a Cell-free Enzymatic Cascade for the Production of GDP-Fucose. ISGSB2022 Conference, Innsbruck, Austria (2022)

Juárez-Osorio, M.; Darr , A.; Volckmar, J.; Bruder, D.; Rexer, T.; Reichl, U.: Towards full control over protein glycosylation: In-vitro glycoengineering of Influenza A virus Hemagglutinin and SARS-CoV-2 spike protein. 32nd Glycobiology Meeting, Utrecht (The Netherlands) (2022)

Khesali Aghtaei, H.; Benndorf, D.; Reichl, U.: Biological methanation using a tubular foam bioreactor. Smart Process Systems Engineering 2022 Towards Sustainable & Circular Production Processes (SmartProSys 2022), Magdeburg, Germany (2022)

Khesali Aghtaei, H.; Benndorf, D.; Sczyrba, A.; Reichl, U.: Adaptation of a methanogenic community to demand-oriented biological methanation. 4th International Metaproteomics Symposium, Luxembourg, Luxembourg (2022)

Kupke, S. Y.; Hein, M.D.; Bdeir, N.; Rand, U.; Marichal-Gallardo, P.; Cicin-Sain, L.; Bruder, D.; Pöhlmann, S.; Schughart, K.; Reichl, U.: Influenza A Virus Defective Interfering Particles for Antiviral Treatment of the Influenza Disease and COVID-19. 31st Annual Meeting of the Society for Virology, online (2022)

Pelz, L.; Rüdiger, D.; Dogra, T.; Alnaji, F.G.; Genzel, Y.; Brooke, C.B.; Kupke, S. Y.; Reichl, U.: Long-Term Propagation of Influenza A Virus and Its Defective Interfering Particles: Analyzing Dynamic Competition to Select Antiviral Candidates. Vaccine Technology VIII, Sitges (Spain) (2022)

Pelz, L.; Rüdiger, D.; Dogra, T.; Alnaji, F. G.; Genzel, Y.; Brooke, C. B.; Kupke, S. Y.; Reichl, U.: Semi-Continuous propagation of Influenza A virus and its defective interfering particles: Analyzing the dynamic competition to select antiviral candidates. 27th ESACT Meeting, Lisbon (Portugal) (2022)

Rüdiger, D.; Küchler, J.; Pontes, C.; Kupke, S. Y.; Reichl, U.: Modeling the intracellular replication of a new type of defective interfering particle of influenza virus with genomic nucleotide substitutions. 12th European Conference on Mathematical and Theoretical Biology, Heidelberg (Germany) (2022)

Ruhnau, J.: Cell-free Glycoengineering of the recombinant SARS-CoV-2 spike glycoprotein. 15th Bratislava Symposium on Saccharides (15BSS) , Smolenice (Slovakia) (2022)

Zinnecker, T. M.; Behrendt, I.; Lau , M.; Hinkelmann, A.; Thiele, K.; Badri, N.; Araujo, D.; Genzel, Y.; Reichl, U.: Automated single-cell cloning in chemically defined medium for new suspension MDCK cell lines and scale-down of influenza A virus production into ambr^®15 microbioreactors. Vaccine Technology VIII, Sitges (Spain) (2022)

Dogra, T.; Pelz, L.; Marc, H.; Rüdiger, D.; Boehme, J.; Bruder, D.; Kupke, S. Y.; Reichl, U.: Reverse genetics for Influenza A virus to generate genetically engineered defective interfering particles for antiviral treatment and vaccination. 27th ESACT Meeting, Lisbon (Portugal) (2022)

Göbel, S.; Dorn, M.; Jaén Chavez, K.; Jordan, I.; Sandig, V.; Altomonte, J.; Genzel, Y.; Reichl, U.: Production of a fusogenic oncolytic rVSV-NDV virus in perfusion processes. Vaccine Technology VIII, Sitges (Spain) (2022)

Göbel, S.; Jordan, I.; Sandig, V.; Altomonte, J.; Genzel, Y.; Reichl, U.: Towards the production of a fusogenic oncolytic rVSV-NDV virus in perfusion mode. 27th ESACT Meeting, Lisbon (Portugal) (2022)

Göbel, S.; Kortum, F.; Jaén Chavez, K.; Jordan, I.; Sandig, V.; Altomonte, J.; Genzel, Y.; Reichl, U.: Production of a fusogenic oncolytic VSV-NDV virus: cell-line screening and process development in small-scale suspension cultures. Advancing Manufacture of Cell and Gene Therapies VII, Coronado, CA (USA) (2022)

Hein, M.; Chawla, A.; Arora , P.; Cattaneo, M.; Winkler, M.; Pöhlmann, S.; Genzel, Y.; Kupke, S. Y.; Reichl, U.: Production of influenza A virus-derived defective interfering particles for antiviral therapy in a high cell density perfusion cultivation. 27th ESACT Meeting, Lisbon (Portugal) (2022)

Hellwig, P.; Dittrich, A.; Benndorf, D.; Reichl, U.: Establishment of a click chemistry-based method for detection and characterizationof phage-host systems in anaerobic digestion. 2nd German Phage Symposium, Stuttgart, Germany (2022)

Hellwig, P.; Heyer, R.; Maus, I.; Meinusch, N.; Walke, D.; Schlüter, A.; Hassa, J.; Sczyrba, A.; Klocke, M.; Mächtig, T. et al.; Schallert, K.; Seick, I.; Saake, G.; Reichl, U.; Benndorf, D.: Combined metagenomics and metaproteomics for analysis of the microbial community in a two-stage biogas plant. XIV Annual Congress of the European Proteomic Association, Leipzig, Germany (2022)

Hoang Son, T.; Lange, F.; Mahour, R.; Rexer, T.; Reichl, U.: In-vitro multi-enzyme cascades for the synthesis of UDP-galactose and UDP-N-acetylglucosamine. 32nd Joint Glycobiology Meeting, Utrecht, The Netherlands (2022)

Hoang Son, T.; Mahour, R.; Rexer, T.; Reichl, U.: In-vitro multi-enzyme cascades for the synthesis of UDP-galactose and UDP-N-acetylglucosamine. 10th International Congress on Biocatalysis (Biocat2022), Hamburg, Germany (2022)

Huber, N.; Alcalá Orozco, E. A.; Rexer, T.; Reichl, U.; Klamt, S.: Dynamic Modeling and Optimization of a Cell-free Enzymatic Cascade for the Production of GDP-Fucose. ISGSB2022 Conference, Innsbruck, Austria (2022)

Huber, N.; Alcalá Orozco, E. A.; Rexer, T.; Reichl, U.; Klamt, S.: Dynamic Modeling and Optimization of a Cell-free Enzymatic Cascade for the Production of GDP-Fucose. Metabolic Pathway Analysis, Seoul, Korea (2022)

Khesali Aghtaei, H.; Benndorf, D.; Reichl, U.: Power to gas: Impact of changes in H₂ supply on performance and microbial community composition of a biological methanation process. Himmelfahrtstagung on Bioprocess Engineering 2022 - Future Bioprocesses for a Sustainable Industry (DECHEMA), Mainz, Germany (2022)

Khesali Aghtaei, H.; Benndorf, D.; Reichl, U.: Development of a tubular foam bioreactor for biological methanation. 8th International Conference on Renewable Energy Gas Technology (REGATEC 2022), Malmö, Sweden (2022)