Publications BPE group
Journal Article (10)
2007
Journal Article
46 (13), pp. 4686 - 4694 (2007)
Hydrodynamic characteristics and expansion behavior of beds containing single and binary-mixtures of particles. Industrial and Engineering Chemistry Research
Journal Article
25 (20), pp. 3987 - 3995 (2007)
Establishment of a mink enteritis vaccine production process in stirred-tank reactor and Wave Bioreactor microcarrier culture in 1-10 L scale. Vaccine
Journal Article
97 (1), pp. 73 - 85 (2007)
Harvesting and concentration of human influenza A virus produced in serum-free mammalian cell culture for the production of vaccines. Biotechnology and Bioengineering
Journal Article
299, pp. 251 - 260 (2007)
Direct capture of influenza A virus from cell culture supernatant with Sartobind anion-exchange membrane adsorbers. Journal of Membrane Science
Journal Article
96, pp. 932 - 944 (2007)
Purification of cell culture-derived human influenza A virus by size-exclusion and anion-exchange chromatography. Biotechnology and Bioengineering
Journal Article
23 (18), pp. 9271 - 9281 (2007)
Concentration Polarization and Nonequilibrium Electroosmotic Slip in Dense Multiparticle Systems. Langmuir
Journal Article
5, p. 46 (2007)
Visualizing Regulatory Interactions in Metabolic Networks. BMC Biology
Journal Article
131 (3), pp. 309 - 317 (2007)
Impact of adsorbents selection on affinity purification efficiency of cell culture derived human Influenza viruses. Journal of Biotechnology
Journal Article
25 (5), pp. 939 - 947 (2007)
Lectin-affinity chromatography for downstream processing of MDCK cell culture derived human influenza A viruses. Vaccine
Journal Article
26 (12), pp. 1552 - 1565 (2007)
Development and optimisation of a procedure for the production of Parapoxvirus Ovis by large scale microcarrier cell culture in a non animal, non human and non plant derived medium. Vaccine Book Chapter (3)
2007
Book Chapter
Vaccine production - state of the art and future needs in upstream processing. In: Animal Cell Biotechnology: Methods and Protocols, pp. 457 - 473 (Ed. Pörtner, R.). HUMANA Press Inc., Totowa, New Jersey (2007)
Book Chapter
Dynamics of Virus-Host Cell Interaction. In: Bioinformatics: From Genomes to Therapies, pp. 861 - 898 (Ed. Lengauer, T.). Wiley-VCH, Weinheim (2007)
Book Chapter
Monitoring of Extracellular TCA Cycle Intermediates in Mammalian Cell Culture. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 603 - 605 (Ed. Smith, R.). Springer, Dordrecht, The Netherlands (2007)
Conference Paper (7)
2007
Conference Paper
Closed loop control of perfusion systems in high-density cell culture. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 549 - 551 (Ed. Smith, R.). 19th ESACT Meeting, Harrogate, UK, June 05, 2005 - June 08, 2005. Springer, Dordrecht, The Netherlands (2007)
Conference Paper
Serum-free influenza vaccine production with MDCK cells in wave-bioreactor and 5L-stirred tank bioreactor. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 563 - 565 (Ed. Smith, R.). 19th ESACT Meeting , Harrogate, UK, June 05, 2005 - June 08, 2005. Springer, Dordrecht, The Netherlands (2007)
Conference Paper
Influenza Vaccines: Challenges in Mammalian Cell Culture Technology. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 503 - 508 (Ed. Smith, R.). 19th ESACT Meeting, Harrogate, UK, June 05, 2005 - June 08, 2005. Springer, Dordrecht, The Netherlands (2007)
Conference Paper
Cultivation of E-FL in Perfusion Mode Using Wave Bioreactor and Stirre-Tank Reactor for Parvovirus Vaccine Production. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 519 - 522 (Ed. Smith, R.). 19th ESACT Meeting, Harrogate, UK, June 05, 2005 - June 08, 2005. Springer, Dordrecht, The Netherlands (2007)
Conference Paper
Strategies for Large Scale Production of Parapoxvirus Ovis NZ-2. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 707 - 710 (Ed. Smith, R.). 19th ESACT Meeting, Harrogate, UK, June 05, 2005 - August 06, 2005. Springer, Dordrecht, The Netherlands (2007)
Conference Paper
7, pp. 191 - 208. Ringberg-Symposium, Kreuth, Germany, May 03, 2006 - May 05, 2006. (2007)
Biological Fundamentals, Models and Technologies for Vaccine Production. In: Perspectives of Research - Identification and Implementation of Research Topics by Organizations: Ringberg-Symposium Mai 2006, Vol.
Conference Paper
Monitoring of Cell Physiology in Influenza Vaccine Production by Flow Cytometry. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 531 - 533 (Ed. Smith, R.). 19th ESACT Meeting, Harrogate, UK, June 05, 2005 - August 06, 2005. Springer, Dordrecht, The Netherlands (2007)
Meeting Abstract (1)
2007
Meeting Abstract
1, p. 5. BioSysBio 2007 : Systems Biology, Bioinformatics and Synthetic Biology, Manchester, UK, January 11, 2007 - January 13, 2007. (2007)
Visualizing regulatory interactions in metabolic networks. In BMC Systems Biology, Talk (22)
2007
Talk
Vero or MDCK cells for influenza A virus production in microcarrier systems? European BioPerspectives 2007, Cologne, Germany (2007)
Talk
Implementation of analytical methods during upstream processing for an influenza A virus production process. Vaccine Production : Analytical Methods, Characterisation, Scale-up and Manufacturing, Cologne, Germany (2007)
Talk
Lectin-affinity chromatography: a novel purification method for cell culture based Influenza vaccine production from the current season 2006/07. European BioPerspectives 2007, Cologne, Germany (2007)
Talk
Lektin-Affinitätschromatographie - Neuartige Methode zur Aufreinigung humaner Influenza Viren aus Zellkulturen zur Impfstoffproduktion. DECHEMA/GVC Vortrag- und Diskussionstagung "Aufarbeitung biotechnologischer Produkte", Osnabrück, Germany (2007)
Talk
Efficient influenza virus capture from cell cultivation broth by a novel affinity chromatography. AIChE Annual meeting 2007, Salt Lake City, USA (2007)
Talk
Novel capturing method for currently spread influenza viruses from cell cultures by affinity separation. ISPPP 2007, Orlando, USA (2007)
Talk
Characterisation of Glycosylation Patterns Utilizing a DNA-Sequenzer and Mass Spectrometry. 14th European Carbohydrate Symposium, Lübeck, Germany (2007)
Talk
Characterisation of Glycosylation Patterns Utilizing a DNA-Sequenzer and a MALDI-TOF Mass Spectrometer. 7th Carbohydrate Bioengineering Meeting (CBM7), Braunschweig, Germany (2007)
Talk
Elucidation of the Influenza A Virus Glycosylation Patterns with Respect to Vaccine Production Down to the Lower Zeptomolar Range. 21st International Symposium on MicroScale Bioseparations (MSB), Vancouver, BC, Canada (2007)
Talk
Quantitative proteomic analysis of influenza A virus infected mammalian cells: Elucidation of virus / host cell interactions with respect to the vaccine production process. 27th International Symposium & Exhibit on the Separation of Proteins, Peptides & Polynucleotides (ISPPP 2007), Orlando, USA (2007)
Talk
A Systems Perspective of Virus Replication in Mammalian Cell Cultures. Meeting at MPI Golm, Potsdam-Golm, Germany (2007)
Talk
Influenza Vaccines: Challenges in Optimization of Virus Yields in Mammalian Cell Culture. Vaccine Congress, Amsterdam, The Netherlands (2007)
Talk
Characterization of Cell Growth and Influenza Virus Replication in Microcarrier Culture. Kooperationsgespräch bei ROCHE AG, Penzberg, Germany (2007)
Talk
A Systems Perspective of Influenza Virus Replication in Cell Cultures. European Conference on Complex Systems, Dresden, Germany (2007)
Talk
Theoretical and Experimental Characterization of Influenza Virus Replication in Cell Cultures. Meeting Helmholtz-Zentrum, Braunschweig, Germany (2007)
Talk
Theoretical and Experimental Characterization of Influenza Virus Replication in Cell Cultures. DECHEMA-Arbeitsausschuss Biotechnologie, Frankfurt/M., Germany (2007)
Talk
Mathematical Modeling of Mammalian Cell Cultures - Cell Growth and Product Synthesis. MPG-CNRS Treffen, Paris, France (2007)
Talk
MDCK cell derived influenza vaccines - aspects of up- and downstream processing. Meeting Merck & Co., Inc., USA (2007)
Talk
Mathematical Modeling of Mammalian Cell Cultures: From Cell Populations to Individual Cells. Workshop "Systems biology", Leipzig, Germany (2007)
Talk
Metabolite Analysis in Mammalian Cells: How to generate reliable data sets? 20th ESACT meeting, Dresden, Germany (2007)
Talk
A Medically Relevant Three-Species Mixed Culture in a Chemostat: Mathematical Modelling and Experiments to Study Interaction Effects. European BioPerspectives 2007, Cologne, Germany (2007)
Talk
N-glycan analysis method for cell culture derived influenza virus hemagglutinin. Joint Meeting 2007, Lille, France (2007)
Poster (24)
2007
Poster
Higher yields in influenza vaccine production using perfusion in high-density cell culture. Vaccine Congress, Amsterdam, The Netherlands (2007)
Poster
Monitoring of cell activity: online oxygen uptake rates in pulsed aerated cell culture. 20th ESACT Meeting, Dresden, Germany (2007)
Poster
Online measurement and balancing of dissolved carbon dioxide in cell culture technology. European BioPerspectives, Cologne, Germany (2007)
Poster
Comparing Vero and MDCK cells for influenza A virus production in microcarrier systems. 20th ESACT Meeting , Dresden, Germany (2007)
Poster
Analytical platform for bioprocesses with adherent mammalian cells. MPG-CNRS Joint Workshop on Systems Biology, Berlin, Germany (2007)
Poster
Lectin-affinity chromatography for downstream processing of current influenza virus strains from MDCK and Vero cell cultivations. AIChE Annual meeting 2007, Salt Lake City, USA (2007)
Poster
Elucidation of the Influenza A Virus Glycosylation-Patterns with Respect to Vaccine-Production Down to the Zeptomolar Range. 3rd Glycan Forum Berlin 2007, Berlin-Dahlem, Germany (2007)