Publications BPE group

Journal Article (294)

2021
Journal Article
Bartholomäus, A.; Kolte, B.; Mustafayeva, A.; Goebel, I.; Fuchs, S.; Benndorf, D.; Engelmann, S.; Ignatova, Z.: smORFer: a modular algorithm to detect small ORFs in prokaryotes. Nucleic Acids Research (London) 49 (15), e89 (2021)
Journal Article
Bastida, F.; Jehmlich, N.; Starke, R.; Schallert, K.; Benndorf, D.; López-Mondéjar, R.; Plaza, C.; Freixino, Z.; Ramírez-Ortuño, C.; Ruiz-Navarro, A. et al.; Díaz-López, M.; Vera, A.; Moreno, J.L.; Eldridge, D.J.; García, C.; Delgado-Baquerizo, M.: Structure and function of bacterial metaproteomes across biomes. Soil Biology and Biochemistry 160, 108331 (2021)
Journal Article
Biemann, R.; Buß, E.; Benndorf, D.; Lehmann, T.; Schallert, K.; Püttker, S.; Reichl, U.; Isermann, B.; Schneider, J. G.; Saake, G. et al.; Heyer, R.: Fecal Metaproteomics Reveals Reduced Gut Inflammation and Changed Microbial Metabolism Following Lifestyle-Induced Weight Loss. Biomolecules 11 (5), 726 (2021)
Journal Article
Bissinger, T.; Wu, Y.; Marichal-Gallardo, P.; Riedel, D.; Liu, X.; Genzel, Y.; Tan, W.; Reichl, U.: Towards integrated production of an influenza A vaccine candidate with MDCK suspension cells. Biotechnology and Bioengineering 118 (10), pp. 3996 - 4013 (2021)
Journal Article
Chuzel, L.; Fossa, S. L.; Boisvert, M. L.; Cajic, S.; Hennig, R.; Ganatra, M. B.; Reichl, U.; Rapp, E.; Taron, C. H.: Combining functional metagenomics and glycoanalytics to identify enzymes that facilitate structural characterization of sulfated N-glycans. Microbial Cell Factories 20 (20), 162 (2021)
Journal Article
De Vrieze, J.; Heyer, R.; Props, R.; Van Meulebroek, L.; Gille, K.; Vanhaecke, L.; Benndorf, D.; Boon, N.: Triangulation of microbial fingerprinting in anaerobic digestion reveals consistent fingerprinting profiles. Water Research 202 (1), 117422 (2021)
Journal Article
Di Marco, F.; Berger, T.; Esser-Skala, W.; Rapp, E.; Regl, C.; Huber, C. G.: Simultaneous Monitoring of Monoclonal Antibody Variants by Strong Cation-Exchange Chromatography Hyphenated to Mass Spectrometry to Assess Quality Attributes of Rituximab-Based Biotherapeutics. International Journal of Molecular Sciences 22 (16), 9072 (2021)
Journal Article
Eussen, S. R. B. M.; Mank, M.; Kottler, R.; Hoffmann, X.-K.; Behne, A.; Rapp, E.; Stahl, B.; Mearin, M. L.; Koletzko, B.: Presence and Levels of Galactosyllactoses and Other Oligosaccharides in Human Milk and Their Variation during Lactation and According to Maternal Phenotype. Nutrients 13 (7), 2324 (2021)
Journal Article
Feichtinger, R. G.; Hüllen, A.; Koller, A.; Kotzot, D.; Grote, V.; Rapp, E.; Hofbauer, P.; Brugger, K.; Thiel, C.; Mayr, J. A. et al.; Wortmann, S. B.: A spoonful of L‐fucose—an efficient therapy for GFUS‐CDG, a new glycosylation disorder. Embo Molecular Medicine 13 (9), e14332 (2021)
Journal Article
Gränicher, G.; Babakhani, M.; Göbel, S.; Jordan, I.; Marichal-Gallardo, P.; Genzel, Y.; Reichl, U.: A high cell density perfusion process for Modified Vaccinia virus Ankara production: process integration with inline DNA digestion and cost analysis. Biotechnology and Bioengineering (2021)
Journal Article
Gränicher, G.; Tapia, F.; Behrendt, I.; Jordan, I.; Genzel, Y.; Reichl, U.: Production of Modified Vaccinia Ankara Virus by Intensified Cell Cultures: A Comparison of Platform Technologies for Viral Vector Production. Biotechnology Journal 16 (1), e2000024 (2021)
Journal Article
Gücüm, S.; Sakson, R.; Hoffmann, M.; Grote, V.; Becker, C.; Pakari, K.; Beedgen, L.; Thiel, C.; Rapp, E.; Ruppert, T. et al.; Thumberger, T.; Wittbrodt, J.: A patient-based medaka alg2 mutant as a model for hypo-N-glycosylation. Development 148 (11), dev199385 (2021)
Journal Article
Hassa, J.; Klang, J.; Benndorf, D.; Pohl, M.; Hülsemann, B.; Mächtig, T.; Effenberger, M.; Pühler, A.; Schlüter, A.; Theuerl, S.: Indicative Marker Microbiome Structures Deduced from the Taxonomic Inventory of 67 Full-Scale Anaerobic Digesters of 49 Agricultural Biogas Plants. Microorganisms 9 (7), 1457 (2021)
Journal Article
Hein, M. D.; Arora, P.; Marichal-Gallardo, P.; Winkler, M.; Genzel, Y.; Pöhlmann, S.; Schughart, K.; Kupke, S. Y.; Reichl, U.: Cell culture-based production and in vivo characterization of purely clonal defective interfering influenza virus particles. BMC Biology 19 (1), 91 (2021)
Journal Article
Hein, M. D.; Chawla, A.; Cattaneo, M.; Kupke, S. Y.; Genzel, Y.; Reichl, U.: Cell culture–based production of defective interfering influenza A virus particles in perfusion mode using an alternating tangential flow filtration system. Applied Microbiology and Biotechnology 105, pp. 7251 - 7264 (2021)
Journal Article
Hein, M. D.; Kollmus, H.; Marichal-Gallardo, P.; Püttker, S.; Benndorf, D.; Genzel, Y.; Schughart, K.; Kupke, S. Y.; Reichl, U.: OP7, a novel influenza A virus defective interfering particle: production, purification, and animal experiments demonstrating antiviral potential. Applied Microbiology and Biotechnology 105, pp. 129 - 146 (2021)
Journal Article
Lebede, M.; Di Marco, F.; Esser-Skala, W.; Hennig, R.; Wohlschlager, T.; Huber, C. G.: Exploring the Chemical Space of Protein Glycosylation in Noncovalent Protein Complexes: An Expedition along Different Structural Levels of Human Chorionic Gonadotropin by Employing Mass Spectrometry. Analytical Chemistry 93, pp. 10424 - 10434 (2021)
Journal Article
Litschko, C.; Budde, I.; Berger, M.; Bethe, A.; Schulze, J.; Alcala Orozco, E. A.; Mahour, R.; Goettig, P.; Führing, J. I.; Rexer, T. et al.; Gerardy-Schahn, R.; Schubert, M.; Fiebig, T.: Mix-and-Match System for the Enzymatic Synthesis of Enantiopure Glycerol-3-Phosphate-Containing Capsule Polymer Backbones from Actinobacillus pleuropneumoniae, Neisseria meningitidis, and Bibersteinia trehalosi. mBio 12 (3), e00897-21 (2021)
Journal Article
Mahour, R.; Marichal-Gallardo, P.; Rexer, T.; Reichl, U.: Multi-enzyme cascades for the in vitro synthesis of guanosine diphosphate L-fucose. ChemCatChem 13 (8), pp. 1981 - 1989 (2021)
Journal Article
Marichal-Gallardo, P.; Börner, K.; Pieler, M.; Sonntag-Buck, V.; Obr, M.; Bejarano, D.; Wolff, M. W.; Kräusslich, H.-G.; Reichl, U.; Grimm, D.: Single-use capture purification of adeno-associated viral gene transfer vectors by membrane-based steric exclusion chromatography. Human Gene Therapy 32 (17-18), pp. 959 - 974 (2021)
Journal Article
Meinusch, N.; Kramer, S.; Körner, O.; Wiese, J.; Seick, I.; Beblek, A.; Berges, R.; Illenberger, B.; Illenberger, M.; Uebbing, J. et al.; Wolf, M.; Saake, G.; Benndorf, D.; Reichl, U.; Heyer, R.: Integrated Cycles for Urban Biomass as a Strategy to Promote a CO2-Neutral Society—A Feasibility Study. Sustainability 13 (17), 9505 (2021)
Journal Article
Noor, S. I.; Hoffmann, M.; Rinis, N.; Bartels, M. F.; Winterhalter, P. R.; Hoelscher, C.; Hennig, R.; Himmelreich, N.; Thiel, C.; Ruppert, T. et al.; Rapp, E.; Strahl, S.: Glycosyltransferase POMGNT1 deficiency strengthens N-cadherin-mediated cell-cell adhesion. Journal of Biological Chemistry, 100433 (2021)
Journal Article
Offersgaard, A.; Duarte Hernandez, C. R.; Pihl, A. F.; Costa, R.; Venkatesan, N. P.; Lin, X.; Van Pham, L.; Feng, S.; Fahnøe, U.; Scheel, T. K. H. et al.; Ramirez, S.; Reichl, U.; Bukh, J.; Genzel, Y.; Gottwein, J. M.: SARS-CoV-2 Production in a Scalable High Cell Density Bioreactor. Vaccine 9 (7), 706 (2021)
Journal Article
Pech, S.; Rehberg, M.; Janke, R.; Benndorf, D.; Genzel, Y.; Muth, T.; Sickmann, A.; Rapp, E.; Reichl, U.: Tracking changes in adaptation to suspension growth for MDCK cells: cell growth correlates with levels of metabolites, enzymes and proteins. Applied Microbiology and Biotechnology 105, pp. 1861–1874 - 1874 (2021)
Journal Article
Pelz, L.; Rüdiger, D.; Dogra, T.; Alnaji, F. G.; Genzel, Y.; Brooke, C. B.; Kupke, S. Y.; Reichl, U.: Semi-continuous propagation of influenza A virus and its defective interfering particles: analyzing the dynamic competition to select candidates for antiviral therapy. Journal of Virology (2021)
Journal Article
Pralow, A.; Hoffmann, M.; Nguyen-Khuong, T.; Pioch, M.; Hennig, R.; Genzel, Y.; Rapp, E.; Reichl, U.: Comprehensive N‐glycosylation analysis of the influenza A virus proteins HA and NA from adherent and suspension MDCK cells. The FEBS Journal 288 (16), pp. 4869 - 4891 (2021)
Journal Article
Pralow, A.; Nikolay, A.; Leon, A.; Genzel, Y.; Rapp, E.; Reichl, U.: Site-specific N-glycosylation analysis of animal cell culture-derived Zika virus proteins. Scientific Reports 11, 5147 (2021)
Journal Article
Puan, K. J.; San Luis, B.; Yusof, N.; Kumar, D.; Andiappan, A. K.; Lee, W.; Cajic, S.; Vuckovic, D.; Chan, J. D.; Döllner, T. et al.; Hou, H. W.; Jiang, Y.; Tian, C.; Agee, M.; Aslibekyan, S.; Auton, A.; Babalola, E.; Bell, R. K.; Bielenberg, J.; Bryc, K.; Bullis, E.; Cameron, B.; Coker, D.; Partida, G. C.; Dhamija, D.; Das, S.; Elson, S. L.; Filshtein, T.; Fletez-Brant, K.; Fontanillas, P.; Freyman, W.; Gandhi, P. M.; Heilbron, K.; Hicks, B.; Hinds, D. A.; Huber, K. E.; Jewett, E. M.; Kleinman, A.; Kukar, K.; Lane, V.; Lin, K.-H.; Lowe, M.; Luff, M. K.; McCreight, J. C.; McIntyre, M. H.; McManus, K. F.; Micheletti, S. J.; Moreno, M. E.; Mountain, J. L.; Mozaffari, S. V.; Nandakumar, P.; Noblin, E. S.; O’Connell, J.; Petrakovitz, A. A.; Poznik, G. D.; Schumacher, M.; Shastri, A. J.; Shelton, J. F.; Shi, J.; Shringarpure, S.; Tran, V.; Tung, J. Y.; Wang, X.; Wang, W.; Weldon, C. H.; Wilton, P.; Rapp, E.; Poidinger, M.; Wang, D. Y.; Soranzo, N.; Lee, B.; Rötzschke, O.: FUT6 deficiency compromises basophil function by selectively abrogating their sialyl-Lewis x expression. Communications Biology 4, 832 (2021)
Journal Article
Rand, U.; Kupke, S. Y.; Shkarlet, H.; Hein, M. D.; Hirsch, T.; Marichal-Gallardo, P.; Cicin-Sain, L.; Reichl, U.; Bruder, D.: Antiviral Activity of Influenza A Virus Defective Interfering Particles against SARS-CoV-2 Replication In Vitro through Stimulation of Innate Immunity. Cells 10 (7), 1756 (2021)
Journal Article
Reichl, U.; Seidel-Morgenstern, A.; Sundmacher, K.; Tsotsas, E.; van Wachem, B.: Forschungsarbeiten am Institut für Verfahrenstechnik der Otto‐von‐Guericke‐Universität Magdeburg. Chemie Ingenieur Technik 93 (3), pp. 345 - 352 (2021)
Journal Article
Rüdiger, D.; Pelz, L.; Hein, M. D.; Kupke, S. Y.; Reichl, U.: Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culture. PLoS Computational Biology 17, e1009357 (2021)
Journal Article
Ruhnau, J.; Grote, V.; Juarez-Osorio, M.; Bruder, D.; Mahour, R.; Rapp, E.; Rexer, T.; Reichl, U.: Cell-Free Glycoengineering of the Recombinant SARS-CoV-2 Spike Glycoprotein. Frontiers in Bioengineering and Biotechnology 9, 699026 (2021)
Journal Article
Starke, R.; Siles, J. A.; Fernandes, M. L. P.; Schallert, K.; Benndorf, D.; Plaza, C.; Jehmlich, N.; Delgado-Baquerizo, M.; Bastida, F.: The structure and function of soil archaea across biomes. Journal of Proteomics 237, 104147 (2021)
Journal Article
Wu, Y.; Bissinger, T.; Genzel, Y.; Liu, X.; Reichl, U.; Tan, W.-S.: High cell density perfusion process for high yield of influenza A virus production using MDCK suspension cells. Applied Microbiology and Biotechnology 105 (4), pp. 1421 - 1434 (2021)
2020
Journal Article
Coronel, J.; Gränicher, G.; Sandig, V.; Noll, T.; Genzel, Y.; Reichl, U.: Application of an Inclined Settler for Cell Culture-Based Influenza A Virus Production in Perfusion Mode. Frontiers in Bioengineering and Biotechnology 8, 672 (2020)
Journal Article
Duvigneau, S.; Dürr, R.; Laske, T.; Bachmann, M.; Dostert, M.; Kienle, A.: Model-based approach for predicting the impact of genetic modifications on product yield in biopharmaceutical manufacturing—Application to influenza vaccine production. PLoS Computational Biology 16 (6), e1007810 (2020)
Journal Article
Gränicher, G.; Coronel, J.; Trampler, F.; Jordan, I.; Genzel, Y.; Reichl, U.: Performance of an Acoustic Settler Versus a Hollow Fiber-Based ATF Technology for Influenza Virus Production in Perfusion. Applied Microbiology and Biotechnology 104, pp. 4877 - 4888 (2020)
Journal Article
Heyer, R.; Klang, J.; Hellwig, P.; Schallert, K.; Kress, P.; Huelsemann, B.; Theuerl, S.; Reichl, U.; Benndorf, D.: Impact of feeding and stirring regimes on the internal stratification of microbial communities in the fermenter of anaerobic digestion plants. Bioresource Technology 314, 123679 (2020)
Journal Article
Hinneburg , H.; Pedersen, J. L.; Bokil, N. J.; Pralow, A.; Schirmeister, F.; Kawahara, R.; Rapp, E.; Saunders, B. M.; Thaysen-Andersen, M.: High-resolution Longitudinal N- And O-glycoprofiling of Human Monocyte-To- Macrophage Transition. Glycobiology 30 (9), pp. 679 - 694 (2020)
Journal Article
Kupke, S. Y.; Ly, L.-H.; Börno, S. T.; Ruff, A.; Timmermann, B.; Vingron, M.; Haas , S.; Reichl, U.: Single-Cell Analysis Uncovers a Vast Diversity in Intracellular Viral Defective Interfering RNA Content Affecting the Large Cell-to-Cell Heterogeneity in Influenza A Virus Replication. Viruses 12 (1), 71 (2020)
Journal Article
Leoz, D.; A., M. L.; Duewer, D. L.; Fung, A.; Liu, L.; Yau, H. K.; Potter, O.; Staples, G. O.; Furuki, K.; Frenkel, R. et al.; Hu, Y.; Sosic, Z.; Zhang, P.; Altmann, F.; Gruber, C.; Shao, C.; Zaia, J.; Evers, W.; Pangelley, S.; Suckau, D.; Wiechmann, A.; Resemann, A.; Jabs, W.; Beck, A.; Froehlich, J. W.; Huang, C.; Li, Y.; Liu, Y.; Sun, S.; Wang, Y.; Seo, Y.; An, H. J.; Reichardt, N.-C.; Ruiz, J. E.; Archer‑Hartmann, S.; Azadi, P.; Bell, L.; Lakos, Z.; An, Y.; Cipollo, J. F.; Pučić-Baković, M.; Štambuk, J.; Lauc, G.; Li, X.; Wang, P. G.; Bock, A.; Hennig, R.; Rapp, E.; Creskey, M.; Cyr, T.; Nakano, M.; Sugiyama, T.; Leung, P. A.; Link‑Lenczowski, P.; Jaworek, J.; Yang, S. J.; Zhang, H.; Kelly, T.; Klapoetke, S.; Cao, R.; Kim, J. Y.; Lee, H. K.; Lee, J.; Yoo, J. S.; Kim, S.; Suh, S.; de Haan, N.; Falck, D.; Lageveen-Kammeijer, G. S.M.; Wuhrer, M.; Emery, R. J.; Kozak, R. P.; Liew, L. P.; Royle, L.; Urbanowicz, P. A.; Packer, N.; Song, X.; Everest-Dass, A.; Lattová, E.; Cajic, S.; Alagesan, K.; Kolarich, D.; Kasali, T.; Lindo, V.; Chen, Y.; Goswami, K.; Gau, B.; Amunugama, R.; Jones, R.; Stroop, C. J. M.; Kato, K.; Yagi, H.; Kondo, S.; Yuen, C.; Harazono, A.; Shi, X.; Magnelli, P.; Kasper, B. T.; Mahal, L. K.; Harvey, D. J.; O'Flaherty, R.; Rudd, P. M.; Saldova, R.; Hecht, E. S.; Muddiman, D. C.; Kang, J.; Bhoskar, P.; Menard, D.; Saati, A.; Merle, C.; Mast, S.; Tep, S.; Truong, J.; Nishikaze, T.; Sekiya, S.; Shafer, A.; Funaoka, S.; Toyoda, M.; de Vreugd, P.; Caron, C.; Pradhan, P.; Tan, N. C.; Mechref, Y.; Patil, S.; Rohrer, J. S.; Chakrabarti, R.; Dadke, D.; Lahori, M.; Zou, C.; Cairo, C. W.; Reiz, B.; Whittal, R. M.; Lebrilla, C.; Wu, L. D.; Guttman, A.; Szigeti, M.; Kremkow, B. G.; Lee, K.; Sihlbom, C.; Adamczyk, B.; Jin, C.; Karlsson, N. G.; Örnros, J.; Larson, G.; Nilsson, J.; Meyer, B.; Wiegandt, A.; Komatsu, E.; Perreault, H.; Bodnar, E. D.; Said, N.; Francois, Y.; Leize-Wagner, E.; Maier, S.; Zeck, A.; Heck, A. J. R.; Yang, Y.; Haselberg, R.; Yu, Y. Q.; Alley, W.; Leone, J. W.; Yuan, H.; Stein, S. E.: NIST interlaboratory study on glycosylation analysis of monoclonal antibodies: comparison of results from diverse analytical methods. Molecular and Cellular Proteomics 19 (1), pp. 11 - 30 (2020)
Journal Article
Maus, I.; Tubbesing, T.; Wibberg, D.; Heyer, R.; Hassa, J.; Tomazetto, G.; Huang, L.; Bunk, B.; Spröer, C.; Benndorf, D. et al.; Zverlov, V.; Pühler, A.; Klocke, M.; Sczyrba, A.; Schlüter, A.: The Role of Petrimonas mucosa ING2-E5AT in Mesophilic Biogas Reactor Systems as Deduced from Multiomics Analyses. Microorganisms 8 (12), 2024 (2020)
Journal Article
Nikolay, A.; de Grooth, J.; Genzel, Y.; Wood, J. A.; Reichl, U.: Virus harvesting in perfusion culture: Choosing the right typeof hollow fiber membrane. Biotechnology and Bioengineering 117 (10), pp. 3040 - 3052 (2020)
Journal Article
Patenaude, A.; Erhardt, J.; Hennig, R.; Rapp, E.; Lauc, G.; Pezer, M.: N‐glycosylation analysis of mouse immunoglobulin G isolated from dried blood spots. Electrophoresis (2020)
Journal Article
Rexer, T.; Wenzel, L.; Hoffmann, M.; Tischlik, S.; Bergmann, C.; Grote, V.; Boecker, S.; Bettenbrock, K.; Schildbach, A.; Kottler, R. et al.; Mahour, R.; Rapp, E.; Pietzsch, M.; Reichl, U.: Synthesis of lipid-linked oligosaccharides by a compartmentalized multi-enzyme cascade for the in vitro N-glycosylation of peptides. Journal of Biotechnology 322 (10), pp. 54 - 65 (2020)
Journal Article
Rodrigues Correia Ramos, J.; Rath, A.; Genzel, Y.; Sandig, V.; Reichl, U.: A dynamic model linking cell growth to intracellular metabolism and extracellular by‐product accumulation. Biotechnology and Bioengineering 117 (5), pp. 1533 - 1553 (2020)
Journal Article
Rodrigues, A. F.; Fernandes, P.; Laske, T.; Castro, R.; Marques Alves, P.; Genzel, Y.; Coroadinha, A. S.: Cell Bank Origin of MDCK Parental Cells Shapes Adaptation to Serum-Free Suspension Culture and Canine Adenoviral Vector Production. International Journal of Molecular Sciences 21 (17), 6111 (2020)
Journal Article
Schaffert, A.; Hanić, M.; Novokmet, M.; Zaytseva, O.; Krištić, J.; Lux, A.; Nitschke, L.; Peipp, M.; Pezer, M.; Hennig, R. et al.; Rapp, E.; Lauc, G.; Nimmerjahn, F.: Minimal B Cell Extrinsic IgG Glycan Modifications of Pro- and Anti-Inflammatory IgG Preparations in vivo. Frontiers in Immunology 10, 3024 (2020)
Journal Article
Schiebenhoefer, H.; Schallert, K.; Renard, B. Y.; Trappe, K.; Schmid, E.; Benndorf, D.; Riedel, K.; Muth, T.; Fuchs, S.: A complete and flexible workflow for metaproteomics data analysis based on MetaProteomeAnalyzer and Prophane. Nature Protocols 15, pp. 3212 - 3239 (2020)
Journal Article
Scoma, A.; Khor, W. C.; Coma, M.; Heyer, R.; Props, R.; Schoelynk, J.; Bouts, T.; Benndorf, D.; Li, D.; Zhang, H. et al.; Rabaey, K.: Substrate-Dependent Fermentation of Bamboo in Giant Panda Gut Microbiomes: Leaf Primarily to Ethanol and Pith to Lactate. Frontiers in Microbiology 11, 530 (2020)
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