Publications BPE group
Journal Article (27)
2019
Journal Article
14 (3), e0212757 (2019)
A system for production of defective interfering particles in the absence of infectious influenza A virus. PLoS One
Journal Article
37 (47), pp. 7003 - 7010 (2019)
Semi-perfusion cultures of suspension MDCK cells enable high cell concentrations and efficient influenza A virus production. Vaccine
Journal Article
10, 4816 (2019)
Inverting family GH156 sialidases define an unusual catalytic motif for glycosidase action. Nature Communications
Journal Article
29 (5), pp. 349 - 354 (2019)
The minimum information required for a glycomics experiment (MIRAGE) project: LC guidelines. Glycobiology
Journal Article
37 (47), pp. 7011 - 7018 (2019)
Influenza A virus production in a single-use orbital shaken bioreactor with ATF or TFF perfusion systems. Vaccine
Journal Article
24 (19), 3482 (2019)
Enzymatic Cascades for Tailored 13C6 and 15N Enriched Human Milk Oligosaccharides. Molecules
Journal Article
14 (3), 1800305 (2019)
Enzymatic cascade synthesis provides novel linear human milk oligosaccharides as reference standards for xCGE-LIF based high-throughput analysis. Biotechnology Journal
Journal Article
Use of sulfated cellulose membrane adsorbers for chromatographic purification of cell cultured-derived influenza A and B viruses. Separation and Purification Technology (226), pp. 350 - 358 (2019)
Journal Article
37 (47), pp. 7019 - 7028 (2019)
Efficient influenza A virus production in high cell density using the novel porcine suspension cell line PBG.PK2.1. Vaccine
Journal Article
10, 1883 (2019)
A Robust and Universal Metaproteomics Workflow for Research Studies and Routine Diagnostics Within 24 h Using Phenol Extraction, FASP Digest, and the MetaProteomeAnalyzer. Frontiers in Microbiology
Journal Article
Metaproteome analysis reveals that syntrophy, competition, and phage-host interaction shape microbial communities in biogas plants. Microbiome (7), 69 (2019)
Journal Article
91 (7), pp. 4559 - 4567 (2019)
Post-Column Make-Up Flow (PCMF) Enhances the Performance of Capillary-Flow PGC-LC-MS/MS-Based Glycomics. Analytical Chemistry
Journal Article
15 (2), e1006759 (2019)
RedCom: A strategy for reduced metabolic modeling of complex microbial communities and its application for analyzing experimental datasets from anaerobic digestion. PLoS Computational Biology
Journal Article
93 (4), 01786-18 (2019)
A Novel Type of Influenza A Virus-Derived Defective Interfering Particle with Nucleotide Substitutions in Its Genome. Journal of Virology
Journal Article
15 (4), e1006944 (2019)
Model-based analysis of influenza A virus replication in genetically engineered cell lines elucidates the impact of host cell factors on key kinetic parameters of virus growth. PLoS Computational Biology
Journal Article
201, pp. 93 - 103 (2019)
Metaproteomics of fecal samples of Crohn's disease and Ulcerative Colitis. Journal of Proteomics
Journal Article
375 (2), pp. 507 - 529 (2019)
The subcommissural organ and the Reissner fiber: old friends revisited. Cell and Tissue Research
Journal Article
18 (1), pp. 3 - 15 (2019)
High-throughput serum N-glycomics: method comparison and application to study rheumatoid arthritis and pregnancy-associated changes. Molecular and Cellular Proteomics
Journal Article
91 (10), pp. 6413 - 6418 (2019)
Approach for Profiling of Glycosphingolipid Glycosylation by Multiplexed Capillary Gel Electrophoresis Coupled to Laser-Induced Fluorescence Detection to Identify Cell-Surface Markers of Human Pluripotent Stem Cells and Derived Cardiomyocytes. Analytical Chemistry
Journal Article
15 (2), e1006819 (2019)
Multiscale modeling of influenza A virus replication in cell cultures predicts infection dynamics for highly different infection conditions. PLoS Computational Biology
Journal Article
13 (4), pp. 1004 - 1018 (2019)
Reduced TCA cycle rates at high hydrostatic pressure hinder hydrocarbon degradation and obligate oil degraders in natural, deep-sea microbial communities. The ISME Journal
Journal Article
7, 275 (2019)
Production of Defective Interfering Particles of Influenza A Virus in Parallel Continuous Cultures at Two Residence Times—Insights From qPCR Measurements and Viral Dynamics Modeling. Frontiers in Bioengineering and Biotechnology
Journal Article
14 (11), e0224317 (2019)
Continuous influenza virus production in a tubular bioreactor system provides stable titers and avoids the “von Magnus effect”. PLoS One
Journal Article
19 (2), pp. 439 - 455 (2019)
A robust, cost-effective method for DNA, RNA and protein co-extraction from soil, other complex microbiomes, and pure cultures. Molecular Ecology Resources
Journal Article
103 (7), pp. 3025 - 3035 (2019)
High titer MVA and influenza A virus production using a hybrid fed-batch/perfusion strategy with an ATF system. Applied Microbiology and Biotechnology
Journal Article
1117, pp. 103 - 117 (2019)
Hydrophobic-interaction chromatography for purification of influenza A and B virus. Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences
Journal Article
10, 1095 (2019)
Augmenting Biogas Process Modeling by Resolving Intracellular Metabolic Activity. Frontiers in Microbiology Book Chapter (1)
2019
Book Chapter
Purification of New Biologicals Using Membrane-Based Processes. In: Current Trends and Future Developments on (Bio-) Membranes, pp. 123 - 150 (Eds. Basile, A.; Charcosset, C.). Elsevier (2019)
Conference Paper (1)
2019
Conference Paper
Efficient transformation of protein sequence databases to columnar index schema. In: Database and Expert Systems Applications. DEXA 2019, pp. 67 - 72 (Ed. Anderst-Kotsis , G.). DEXA: International Conference on Database and Expert Systems Applications
, Linz, Austria, August 26, 2019 - August 29, 2019. Springer, Cham, Switzerland (2019)
Meeting Abstract (3)
2019
Meeting Abstract
Continuous mode of production for two classes of defective interfering influenza A virus particles as antiviral candidates. In Integrated Continuous Biomanufacturing IV, 76. Biomanufact IV, Ocean Edge Resort Brewster (Cape Cod), Massachusetts, USA , October 06, 2019 - October 10, 2019. (2019)
Meeting Abstract
A single-use chromatographic purification platform for viral gene transfer vectors & viral vaccines. In Proceedings Advancing Manufacture of Cell and Gene Therapies VI, 92. Advancing Manufacture of Cell and Gene Therapies VI, Loews Coronado Bay Hotel Coronado, California, USA, January 27, 2019 - January 31, 2019. (2019)
Meeting Abstract
258, 45-ENFL. ACS Fall National Meeting and Exposition, San Diego, CA, August 25, 2019 - August 29, 2019. (2019)
High-pressure methane adsorption and characterization of pores in Posidonia shales and isolated kerogens. In Abstracts of Papers of the American Chemical Society, Talk (26)
2019
Talk
Recent experimental and bioinformatic developments in metaproteomics. Metaproteomics - The Gateway to Microbial Commmunity Structure-Function Analysis, Sheffield, UK (2019)
Talk
Next-generation production platforms for viral therapies. Simposio Max Planck / Fronteras de la Ciencia Bogotá, Bogota, Colombia (2019)
Talk
Upstream Process Development - From Master Seed to Production. ESACT Cell culture based viral vaccine course, Llafranc, Spanien (2019)
Talk
Upstream Process Intensification. ESACT Cell culture based viral vaccine course, Llafranc, Spanien (2019)
Talk
Orbital Shaken Bioreactors: Perfusion with shaken bioreactors. Kühner Workshop Meeting, San Martin, Spain (2019)
Talk
System diagnostics of the human gut microbiome using metaproteome analysis of fecal samples. Deutscher Kongress für Laboratoriumsmedizin, Magdeburg, Germany (2019)
Talk
Identification of process parameters shaping microbial communities in biogas plants using large scale metaproteome analysis. Annual Conference of the Association for General and Applied Microbiology (VAAM), Mainz, Germany (2019)
Talk
Post-Column Make-up Flow (PCMF) Enhances the Sensitivity of Capillary-Flow PCG-LC-MS/Based Glycomics. GlycoBioTec 2019, Berlin, Germany (2019)
Talk
Biological conversion of CO2 from a biogas plant to CH4. Young Professionals Conference on Process Engineering (YCOPE 2019), Magdeburg (2019)
Talk
A novel type of defective interfering particle for antiviral therapy. 26th ESACT Meeting, Copenhagen, Denmark (2019)
Talk
Production of defective interfering particles of influenza A virus in continuously cultured bioreactors at two residence times - insights from within-host virus dynamics. 4th Workshop on Viral Dynamics, Paris, France (2019)
Talk
A single-use chromatographic purification platform for viral gene transfer vectors & viral vaccines. ECI Advancing Manufacture of Cell and Gene Therapies VI, Coronado, United States of America (2019)
Talk
Moderne Methoden der Impfstoffherstellung. Wissenschaft im Rathaus, Magdeburg, Germany (2019)
Talk
Cell Culture-based Viral Vaccines: Process Intensification and Monitoring. Cuba Symposium “Frontiers of Science”, Havanna, Cuba (2019)
Talk
glyXbox CE: A powerful tool in the glycoanalytical toolbox - improving biologics development. GlycoBioTec 2019, Berlin, Germany (2019)
Talk
Dynamics of influenza A virus defective interfering particle replication. DARPA PI-Meeting, Arlington, United States of America (2019)
Talk
Dynamics of influenza A virus defective interfering particle replication. DARPA PI Meeting, New York, United States of America (2019)
Talk
High Yield Viral Vaccine Production: Process Options and Monitoring. 9th ISBioTech Spring Meeting, Norfolk, USA (2019)