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Journal Article (79)

2009
Journal Article
Lohr, V.; Rath, A.; Genzel, Y.; Jordan, I.; Sandig, V.; Reichl, U.: New avian suspension cell lines provide production of influenza virus and MVA in serum-free media: studies on growth, metabolism and virus propagation. Vaccine 27 (36), pp. 4975 - 4982 (2009)
Journal Article
Schulze-Horsel, J.; Schulze, M.; Agalaridis, G.; Genzel, Y.; Reichl, U.: Infection dynamics and virus-induced apoptosis in cell culture-based influenza vaccine production – flow cytometry and mathematical modeling. Vaccine 27 (20), pp. 2712 - 2722 (2009)
Journal Article
Schwarzer, J.; Rapp, E.; Hennig, R.; Genzel, Y.; Jordan, I.; Sandig, V.; Reichl, U.: Glycan analysis in cell culture-based influenza vaccine production: Influence of host cell line and virus strain on the glycosylation pattern of viral hemagglutinin. Vaccine 27 (32), pp. 4325 - 4336 (2009)
Journal Article
Vester, D.; Rapp, E.; Gade, D.; Genzel, Y.; Reichl, U.: Quantitative analysis of cellular proteome alterations in human influenza A virus-infected mammalian cell lines. Proteomics 9 (12), pp. 3316 - 3327 (2009)
2008
Journal Article
Opitz, L.; Zimmermann, A.; Lehmann, S.; Genzel, Y.; Lübben, H.; Reichl, U.; Wolff, M. W.: Capture of cell culture-derived influenza virus by lectins: strain independent, but host cell dependent. Journal of Virological Methods 154 (1-2), pp. 61 - 68 (2008)
Journal Article
Ritter, J. B.; Genzel, Y.; Reichl, U.: Simultaneous extraction of several metabolites of energy metabolism and related substances in mammalian cells: Optimization using experimental design. Analytical Biochemistry 373, pp. 349 - 369 (2008)
Journal Article
Schulze-Horsel, J.; Genzel, Y.; Reichl, U.: Flow cytometric monitoring of influenza A virus infection in MDCK cells during vaccine production. BMC Biotechnology 8, p. 45 (2008)
Journal Article
Sidorenko, Y.; Wahl, A.; Dauner, M.; Genzel, Y.; Reichl, U.: Comparison of Metabolic Flux Distributions for MDCK Cell Growth in Glutamine- and Pyruvate-Containing Media. Biotechnology Progress 24 (2), pp. 311 - 320 (2008)
Journal Article
Wahl, A.; Sidorenko, Y.; Dauner, M.; Genzel, Y.; Reichl, U.: Metabolic flux model for an anchorage-dependent MDCK cell line: Characteristic Growth Phases and Minimum Substrate Consumption Flux Distribution. Biotechnology and Bioengineering 101 (1), pp. 135 - 152 (2008)
2007
Journal Article
Hundt, B.; Best, C.; Schlawin, N.; Kassner, H.; Genzel, Y.; Reichl, U.: Establishment of a mink enteritis vaccine production process in stirred-tank reactor and Wave Bioreactor microcarrier culture in 1-10 L scale. Vaccine 25 (20), pp. 3987 - 3995 (2007)
Journal Article
Kalbfuss, B.; Genzel, Y.; Wolff, M. W.; Zimmermann, A.; Morenweiser, R.; Reichl, U.: Harvesting and concentration of human influenza A virus produced in serum-free mammalian cell culture for the production of vaccines. Biotechnology and Bioengineering 97 (1), pp. 73 - 85 (2007)
2006
Journal Article
Genzel, Y.; Fischer, M.; Reichl, U.: Serum-free influenza virus production avoiding washing steps & medium exchange in large-scale microcarrier culture. Vaccine 24, pp. 3261 - 3272 (2006)
Journal Article
Genzel, Y.; Olmer, R. M.; Schäfer, B.; Reichl, U.: Wave microcarrier cultivation of MDCK cells for influenza virus production in serum containing and serum-free media. Vaccine 24 (35-36), pp. 6074 - 6087 (2006)
Journal Article
Ritter, J. B.; Genzel, Y.; Reichl, U.: High-performance anion-exchange chromatography using on-line electrolytic eluent generation for the determination of more than 25 intermediates from energy metabolism of mammalian cells in culture. Journal of Chromatography B 843 (2), pp. 216 - 226 (2006)
2005
Journal Article
Genzel, Y.; Ritter, J. B.; König, S.; Alt, R.; Reichl, U.: Substitution of glutamine by pyruvate to reduce ammonia formation and growth inhibition of mammalian cells. Biotechnology Progress 21 (1), pp. 58 - 69 (2005)
2004
Journal Article
Genzel, Y.; Behrendt, I.; König, S.; Sann, H.; Reichl, U.: Metabolism of MDCK Cells during cell growth and influenza virus production in large-scale microcarrier culture. Vaccine 22, pp. 2202 - 2208 (2004)
Journal Article
Genzel, Y.; König, S.; Reichl, U.: Amino acid analysis in mammalian cell culture media containing serum and high glucose concentrations by anion exchange chromatography and integrated pulsed amperometric detection. Analytical Biochemistry 335, pp. 119 - 125 (2004)
Journal Article
Genzel, Y.; Reichl, U.: Bioprozesstechnik und Impfstoff-Forschung an der Elbe. Bioforum 27 (5), pp. 44 - 46 (2004)
2002
Journal Article
Genzel, Y.; Reichl, U.: Analysis of cell growth, virus replication and medium composition in equine influenza vaccine production. Chemie-Ingenieur-Technik 74 (5), pp. 673 - 674 (2002)

Book Chapter (5)

2020
Book Chapter
Bürgin, T.; Coronel, J.; Hagens, G.; Keebler, M. V.; Genzel, Y.; Reichl, U.; Anderlei, T.: Orbitally Shaken Single-Use Bioreactor for Animal Cell Cultivation: Fed-Batch and Perfusion Mode. In: Animal Cell Biotechnology, pp. 105 - 123. Humana, New York (2020)
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