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Journal Article (70)

  1. Journal Article
    Hundt, B.; Best, C.; Schlawin, N.; Kassner, H.; Genzel, Y.; Reichl, U.: Establishment of a mink enteritis vaccine production process in stirred-tank reactor and Wave Bioreactor microcarrier culture in 1-10 L scale. Vaccine 25 (20), pp. 3987 - 3995 (2007)
  2. Journal Article
    Kalbfuss, B.; Genzel, Y.; Wolff, M. W.; Zimmermann, A.; Morenweiser, R.; Reichl, U.: Harvesting and concentration of human influenza A virus produced in serum-free mammalian cell culture for the production of vaccines. Biotechnology and Bioengineering 97 (1), pp. 73 - 85 (2007)
  3. Journal Article
    Genzel, Y.; Fischer, M.; Reichl, U.: Serum-free influenza virus production avoiding washing steps & medium exchange in large-scale microcarrier culture. Vaccine 24, pp. 3261 - 3272 (2006)
  4. Journal Article
    Genzel, Y.; Olmer, R. M.; Schäfer, B.; Reichl, U.: Wave microcarrier cultivation of MDCK cells for influenza virus production in serum containing and serum-free media. Vaccine 24 (35-36), pp. 6074 - 6087 (2006)
  5. Journal Article
    Ritter, J. B.; Genzel, Y.; Reichl, U.: High-performance anion-exchange chromatography using on-line electrolytic eluent generation for the determination of more than 25 intermediates from energy metabolism of mammalian cells in culture. Journal of Chromatography B 843 (2), pp. 216 - 226 (2006)
  6. Journal Article
    Genzel, Y.; Ritter, J. B.; König, S.; Alt, R.; Reichl, U.: Substitution of glutamine by pyruvate to reduce ammonia formation and growth inhibition of mammalian cells. Biotechnology Progress 21 (1), pp. 58 - 69 (2005)
  7. Journal Article
    Genzel, Y.; König, S.; Reichl, U.: Amino acid analysis in mammalian cell culture media containing serum and high glucose concentrations by anion exchange chromatography and integrated pulsed amperometric detection. Analytical Biochemistry 335, pp. 119 - 125 (2004)
  8. Journal Article
    Genzel, Y.; Behrendt, I.; König, S.; Sann, H.; Reichl, U.: Metabolism of MDCK Cells during cell growth and influenza virus production in large-scale microcarrier culture. Vaccine 22, pp. 2202 - 2208 (2004)
  9. Journal Article
    Genzel, Y.; Reichl, U.: Bioprozesstechnik und Impfstoff-Forschung an der Elbe. Bioforum 27 (5), pp. 44 - 46 (2004)
  10. Journal Article
    Genzel, Y.; Reichl, U.: Analysis of cell growth, virus replication and medium composition in equine influenza vaccine production. Chemie-Ingenieur-Technik 74 (5), pp. 673 - 674 (2002)

Book Chapter (3)

  1. Book Chapter
    Genzel, Y.; Rödig, J.; Rapp, E.; Reichl, U.: Vaccine production: Upstream processing with adherent or suspension cell lines. In: Animal Cell Biotechnology: Methods and Protocols, pp. 371 - 393 (Ed. Pörtner, R.). HUMANA Press Inc., New York (2014)
  2. Book Chapter
    Genzel, Y.; Reichl, U.: Vaccine production - state of the art and future needs in upstream processing. In: Animal Cell Biotechnology: Methods and Protocols, pp. 457 - 473 (Ed. Pörtner, R.). HUMANA Press Inc., Totowa, New Jersey (2007)
  3. Book Chapter
    Ritter, J. B.; Genzel, Y.; Reichl, U.: Monitoring of Extracellular TCA Cycle Intermediates in Mammalian Cell Culture. In: Cell Technology for Cell Products: Proceedings of the 19th ESACT Meeting, pp. 603 - 605 (Ed. Smith, R.). Springer, Dordrecht, The Netherlands (2007)

Conference Paper (15)

  1. Conference Paper
    Lohr, V.; Rath, A.; Jordan, I.; Sandig, V.; Genzel, Y.; Reichl, U.: Avian Designer Cells AGE1.CR as Candidates for MVA and Influenza Vaccine Production. In: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), pp. 615 - 631 (Eds. Jenkins, N.; Barron, N.; Alves, P.). 21st ESACT Meeting, Dublin, Ireland, June 07, 2009 - June 10, 2009. (2012)
  2. Conference Paper
    Öncül, A. A.; Genzel, Y.; Reichl, U.; Thévenin, D.: Flow characterization in wave bioreactors using Computational Fluid Dynamics. In: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), pp. 455 - 469 (Eds. Jenkins, N.; Barron, N.; Alves, P.). 21st ESACT Meeting, Dublin, Ireland, June 07, 2009 - June 10, 2009. Dordrecht (2012)
  3. Conference Paper
    Bock, A.; Genzel, Y.; Reichl, U.: Monitoring of Cell activity: online oxygen uptake rates in pulsed aerated cell culture. In: Cells and Culture: Proceedings of the 20th ESACT Meeting, pp. 391 - 396 (Ed. Noll, T.). 20th ESACT Meeting, Dresden, Germany, June 17, 2007 - June 20, 2007. (2010)
  4. Conference Paper
    Genzel, Y.; Dietzsch, C.; Reichl, U.: Comparing Vero and MDCK cells for influenza A virus production in microcarrier systems. In: Cells and Culture: Proceedings of the 20th ESACT Meeting, pp. 635 - 638 (Ed. Noll, T.). 20th ESACT Meeting, Dresden, Germany, June 17, 2007 - June 20, 2007. (2010)
  5. Conference Paper
    Öncül, A.A.; Janiga, G.; Genzel, Y.; Reichl, U.; Thévenin, D.: Two-population CFD simulation: microcarrier system for adherent cell growth in Wave Bioreactors. In: 4th International Conference on Population Balance Modelling: PBM 2010, pp. 667 - 681. 4th International Conference on Population Balance Modelling, Berlin, Germany, September 15, 2010 - September 17, 2010. (2010)
  6. Conference Paper
    Ritter, J. B.; Genzel, Y.; Reichl, U.: Metabolite Analysis in Mammalian Cells: How to generate reliable data sets? In: Cells and Culture: Proceedings of the 20th ESACT Meeting, pp. 397 - 406 (Ed. Noll, T.). 20th ESACT Meeting, Dresden, Germany, June 17, 2007 - June 20, 2007. (2010)
  7. Conference Paper
    Schulze-Horsel, J.; Schulze, M.; Genzel, Y.; Reichl, U.: Single-cell approach in influenza vaccine production: apoptosis and virus protein production. In: Cells and Culture: Proceedings of the 20th ESACT Meeting, pp. 25 - 28 (Ed. Noll, T.). 20th ESACT Meeting, Dresden, Germany, June 17, 2007 - June 20, 2007. (2010)
 
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