Publications of Hartmut Grammel

Carius, L.; Rumschinski, P.; Faulwasser, T.; Flockerzi, D.; Grammel, H.; Findeisen, R.: Model-based derivation, analysis and control of unstable microaerobic steady-states-Considering Rhodospirillum rubrum as an example. Biotechnology and Bioengineering 111 (4), pp. 734 - 747 (2014)

Carius, L.; Carius, A. B.; McIntosh, M.; Grammel, H.: Quorum sensing influences growth and photosynthetic membrane production in high-cell-density cultivations of Rhodospirillum rubrum. BMC Microbiology 13, 189 (2013)

Carius, L.; Hädicke, O.; Grammel, H.: Stepwise reduction of the culture redox potential allows the analysis of microaerobic metabolism and photosynthetic membrane synthesis in Rhodospirillum rubrum. Biotechnology and Bioengineering 110 (2), pp. 573 - 585 (2013)

Franz, A.; Rehner, R.; Kienle, A.; Grammel, H.: Rapid selection of glucose-utilizing variants of the polyhydroxyalkanoate producer Ralstonia eutropha H16 by incubation with high substrate levels. Letters in Applied Microbiology 54 (1), pp. 45 - 51 (2012)

Rudolf, C.; Grammel, H.: Fructose metabolism of the purple non-sulfur bacterium Rhodospirillum rubrum: Effect of carbon dioxide on growth, and production of bacteriochlorophyll and organic acids. Enzyme and Microbial Technology 50 (4-5), pp. 238 - 246 (2012)

Wang, G.-S.; Grammel, H.; Abou-Aisha, K.; Sägesser, R.; Gosh, R.: High-Level Production of the Industrial Product Lycopene by the Photosynthetic Bacterium Rhodospirillum rubrum. Applied and Environmental Microbiology 78 (20), pp. 7205 - 7215 (2012)

Carius, A. B.; Henkel, M.; Grammel, H.: Glutathione Redox Effect on Photosynthetic Membrane Expression in Rhodospirillum rubrum. Journal of Bacteriology 193 (8), pp. 1893 - 1900 (2011)

Hädicke, O.; Grammel, H.; Klamt, S.: Metabolic network modeling of redox balancing and biohydrogen production in purple nonsulfur bacteria. BMC Systems Biology 5, 150 (2011)

Janke, R.; Genzel, Y.; Freund, S.; Wolff, M. W.; Grammel, H.; Rühmkorf, C.; Seidemann, J.; Wahl, A.; Reichl, U.: Expression, purification, and characterization of a His6-tagged glycerokinase from Pichia farinosa for enzymatic cycling assays in mammalian cells. Journal of Biotechnology 150 (3), pp. 396 - 403 (2010)

Zeiger, L.; Grammel, H.: Model-based high cell density cultivation of Rhodospirillum rubrum under respiratory dark conditions. Biotechnology and Bioengineering 105 (4), pp. 729 - 739 (2010)

Antoniukas, L.; Grammel, H.; Sasnauskas, K.; Reichl, U.: Profiling of external metabolites during production of hantavirus nucleocapsid protein with recombinant Saccharomyces cerevisiae. Biotechnology Letters 30 (3), pp. 415 - 420 (2008)

Grammel, H.; Ghosh, R.: Redox state dynamics of ubiquinone-10 imply cooperative regulation of photosynthetic membrane expression in Rhodospirillum rubrum. Journal of Bacteriology 190 (14), pp. 4912 - 4921 (2008)

Klamt, S.; Grammel, H.; Straube, R.; Ghosh, R.; Gilles, E. D.: Modeling the electron transport chain of purple non-sulfur bacteria. Molecular Systems Biology 4, 156 (2008)

Antoniukas, L.; Grammel, H.; Reichl, U.: Production of hantavirus Puumala nucleocapsid protein in Saccharomyces cerevisiae for vaccine and diagnostics. Journal of Biotechnology 124 (2), pp. 347 - 362 (2006)

Grammel, H.; Gilles, E. D.; Ghosh, R.: Microaerophilic cooperation of reductive and oxidative pathways allows maximal photosynthetic membrane biosynthesis in Rhodospirillum rubrum. Applied and Environmental Microbiology 69 (11), pp. 6577 - 6586 (2003)

Grammel, H.: High Cell Density Culture of Rhodospirillum rubrum and Photosynthetic Membrane Expression under Respiratory Dark Conditions. 13th International Symposium on Phototrophic Prokaryotes, Montreal, Canada (2009)

Zeiger, L.; Grammel, H.: Analysis and Design of Microaerophilic Processes by Combining Computational Models and In-Vivo Spectroscopy. 27. Dechema Jahrestagung der Biotechnologen, Mannheim, Germany (2009)

Grammel, H.: Redox Phenomena in Photosynthetic Bacteria: Applications in Systems Biology and Biotechnology. 1st FORSYS Symposium, Berlin, Germany (2008)

Grammel, H.: Redox Phenomena in Photosynthetic Bacteria: Applications in Systems Biology and Biotechnology. Workshop “Dynamic Systems in Practice”, Magdeburg, Germany (2008)

Streif, S.; Findeisen, R.; Zeiger, L.; Grammel, H.; Janke, R.; Genzel, Y.; Reichl, U.: WPT7: Model Validation, Parameter Analysis and Experimental Design. Part I: Parameter estimation and model invalidation using uncertain data. Part II: Redox Signaling in the facultative photosynthetic bacterium Rhodospirillum rubrum. Part III: Sensitive cycling assays for measuring key metabolic enyzme activities in MDCK cells. FORSYS/FORSYS Partner Status Seminar, Heidelberg, Germany (2011)