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Journal Article (83)

2013
Journal Article
Jordan, I.; Lohr, V.; Genzel, Y.; Reichl, U.; Sandig, V.: Elements in the Development of a Production Process for Modified Vaccinia Virus Ankara. Microorganisms 1 (1), pp. 100 - 121 (2013)
Journal Article
Kluge, S.; Rourou, S.; Vester, D.; Majoul, S.; Benndorf, D.; Genzel, Y.; Rapp, E.; Kallel, H.; Reichl, U.: Proteome analysis of virus-host cell interaction: rabies virus replication in Vero cells in two different media. Applied Microbiology and Biotechnology 97 (12), pp. 5493 - 5506 (2013)
Journal Article
Peschel, B.; Frentzel, S.; Laske, T.; Genzel, Y.; Reichl, U.: Comparison of influenza virus yields and apoptosis-induction in an adherent and a suspension MDCK cell line. Vaccine 31 (48), pp. 5693 - 5699 (2013)
Journal Article
Rehberg, M.; Ritter, J. B.; Genzel, Y.; Flockerzi, D.; Reichl, U.: The relation between growth phases, cell volume changes and metabolism of adherent cells during cultivation. Journal of Biotechnology 164 (4), pp. 489 - 499 (2013)
Journal Article
Rödig, J. V.; Rapp, E.; Bohne, J.; Kampe, M.; Kaffka, H.; Bock, A.; Genzel, Y.; Reichl, U.: Impact of Cultivation Conditions on N-glycosylation of Influenza Virus A Hemagglutinin Produced in MDCK Cell Culture. Biotechnology and Bioengineering 110 (6), pp. 1691 - 1703 (2013)
Journal Article
Tung, S.; Shi, Y.; Wong, K.; Zhu, F.; Gorczynski, R.; Laister, R.; Minden, M.; Blechert, A.-K.; Genzel, Y.; Reichl, U. et al.; Spaner, D. E.: PPARalpha and fatty acid oxidation mediate glucocorticoid resistance in chronic lymphocytic leukemia. Blood 122 (6), pp. 969 - 980 (2013)
2012
Journal Article
Isken, B.; Genzel, Y.; Reichl, U.: Productivity, apoptosis, and infection dynamics of influenza A/PR/8 strains and A/PR/8-based reassortants. Vaccine 30 (35), pp. 5253 - 5261 (2012)
Journal Article
Lohr, V.; Genzel, Y.; Jordan, I.; Katinger, D.; Mahr, S.; Sandig, V.; Reichl, U.: Live attenuated influenza viruses produced in a suspension process with avian AGE1.CR.pIX cells. BMC Biotechnology 12, p. 79 (2012)
2011
Journal Article
Bock, A.; Schulze-Horsel, J.; Schwarzer, J.; Rapp, E.; Genzel, Y.; Reichl, U.: High-density microcarrier cell cultures for influenza virus production. Biotechnology Progress 27 (1), pp. 241 - 250 (2011)
Journal Article
Janke, R.; Genzel, Y.; Händel, N.; Wahl, A.; Reichl, U.: Metabolic adaptation of MDCK cells to different growth conditions: Effects on catalytic activities of central metabolic enzymes. Biotechnology and Bioengineering 108 (11), pp. 2691 - 2704 (2011)
Journal Article
Kalmbach, A.; Bordas, R.; Öncül, A.; Thévenin, D.; Genzel, Y.; Reichl, U.: Experimental Characterization of Flow Conditions in 2- and 20-L Bioreactors with Wave-Induced Motion. Biotechnology Progress 27 (2), pp. 402 - 409 (2011)
Journal Article
Rödig, J.; Rapp, E.; Djeljadini, S.; Lohr, V.; Genzel, Y.; Jordan, I.; Sandig, V.; Reichl, U.: Impact of Influenza Virus Adaptation Status on HA N-Glycosylation Patterns in Cell Culture-Based Vaccine Production. Journal of Carbohydrate Chemistry 30 (4-6), pp. 281 - 290 (2011)
Journal Article
Roedig, J.; Rapp, E.; Höper, D.; Genzel, Y.; Reichl, U.: Impact of Host Cell Line Adaptation on Quasispecies Composition and Glycosylation of Influenza A Virus Hemagglutinin. PLoS One 6 (12), p. e27989 (2011)
2010
Journal Article
Genzel, Y.; Dietzsch, C.; Rapp, E.; Schwarzer, J.; Reichl, U.: MDCK and Vero cells for influenza virus vaccine production: a one-to-one comparison up to lab-scale bioreactor cultivation. Applied Microbiology and Biotechnology 88 (2), pp. 461 - 475 (2010)
Journal Article
Heynisch, B.; Frensing, T.; Heinze, K.; Seitz, C.; Genzel, Y.; Reichl, U.: Differential activation of host cell signaling pathways through infection with two variants of influenza A /Puerto Rico /8/34 (H1N1) in MDCK cells. Vaccine 28 (51), pp. 8210 - 8218 (2010)
Journal Article
Janke, R.; Genzel, Y.; Freund, S.; Wolff, M. W.; Grammel, H.; Rühmkorf, C.; Seidemann, J.; Wahl, A.; Reichl, U.: Expression, purification, and characterization of a His6-tagged glycerokinase from Pichia farinosa for enzymatic cycling assays in mammalian cells. Journal of Biotechnology 150 (3), pp. 396 - 403 (2010)
Journal Article
Janke, R.; Genzel, Y.; Wahl, A.; Reichl, U.: Measurement of Key Metabolic Enzyme Activities in Mammalian Cells Using Rapid and Sensitive Microplate-Based Assays. Biotechnology and Bioengineering 107 (3), pp. 566 - 581 (2010)
Journal Article
Lohr, V.; Genzel, Y.; Behrendt, I.; Scharfenberg, K.; Reichl, U.: A new MDCK suspension line cultivated in a fully defined medium in stirred-tank and wave bioreactor. Vaccine 28 (38), pp. 6256 - 6264 (2010)
Journal Article
Öncül, A.; Kalmbach, A.; Genzel, Y.; Reichl, U.; Thevenin, D.: Characterization of flow conditions in 2 L and 20 L wave bioreactors using Computational Fluid Dynamics. Biotechnology Progress 26 (1), pp. 101 - 110 (2010)
Journal Article
Ritter, J.; Wahl, A.; Freund, S.; Genzel, Y.; Reichl, U.: Metabolic effects of influenza virus infection in cultured animal cells: Intra- and extracellular metabolite profiling. BMC Systems Biology 4, p. 61 (2010)
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