Publications of Frank S. Heldt

Laske, T., Heldt, F. S., Frensing, T., & Reichl, U.Analyzing the intracellular replication of influenza A virus in the presence of defective interfering RNAsPresented at: International Conference on Systems Biology of Human Disease (SBHD)Heidelberg, Germany, July 6, 2015.

Frensing, T., Heldt, S., Bachmann, M., Genzel, Y., Jordan, I., & Reichl, U.CONTINUOUS INFLUENZA VACCINE PRODUCTIONPresented at: Vaccine Technology 2014Playa del Carmen, Mexico, June 8, 2014.

Frensing, T., Heldt, S., Bachmann, M., Genzel, Y., Jordan, I., & Reichl, U.Continuous influenza vaccine productionPresented at: ProcessNet-Jahrestagung und 31. DECHEMA-Jahrestagung der Biotechnologen 2014Aachen, Germany, September 30, 2014.

Heldt, S., Frensing, T., & Reichl, U.A multiscale model of influenza A virus infection that elucidates the treatment with direct-acting antiviralsPresented at: International Conference on Systems Biology of Human Disease 2014 (SBHD)Boston, USA, June 17, 2014.

Laske, T., Heldt, S., Frensing, T., & Reichl, U.Mathematical modeling of virus-host cell interactions during influenza A virus replication supports cell line development for vaccine productionPresented at: 4th International Influenza MeetingMünster, Germany, September 21, 2014.

Frensing, T., Heldt, S., Behrendt, I., Jordan , I., Genzel, Y., & Reichl, U.Continuous production of influenza viruses using avian suspension cellsPresented at: 1st Workshop on Virus DynamicsFrankfurt/Main (Germany), July 15, 2013.

Frensing, T., Heldt, S., Behrendt, I., Jordan, I., Genzel, Y., & Reichl, U.Influenza virus propagation in a continuous cell culture process using avian suspension cellsPresented at: 23rd Annual Meeting of the Society for Virology Kiel, Germany, March 6, 2013.

Frensing, T., Heldt, S., Behrendt, I., Jordan, I., Genzel, Y., & Reichl, U.Continuous production of influenza viruses using avian suspension cellsPresented at: 23rd ESACT Meeting Lille, France, June 23, 2013.

Frensing, T., Heldt, S., Behrendt, I., Jordan, I., Genzel, Y., & Reichl, U.Defective interfering particles hamper continuous influenza virus propagationPresented at: 15th International Negative Strand Virus MeetingGranada (Spain), June 16, 2013.

Frensing, T., Heldt, S., Behrendt, I., Jordan, I., Genzel, Y., & Reichl, U.Continuous influenza virus production in cell culture shows a periodic accumulation of defective interfering particlesPresented at: 7th Vaccine & ISV CongressBarcelona, Spanien, October 27, 2013.

Heldt, S., Isken, B., Pflugmacher, A., Frensing, T., & Reichl, U.A multi-scale model of influenza virus infection elucidates the performance of antiviralsPresented at: 23rd Annual Meeting of the Society for VirologyKiel, Germany, March 6, 2013.

Heldt, S., Peschel, B., Pflugmacher, A., Frensing, T., & Reichl, U.A multi-scale model of influenza virus infection elucidates the performance of antiviralsPresented at: 23rd Annual Meeting of the Society for Virology Kiel, Germany, March 6, 2013.

Frensing, T., Heldt, S., & Reichl, U.Modeling influenza virus replication on a single cell levelPresented at: 3rd International Influenza MeetingMuenster, Germany, September 2, 2012.

Heldt, F. S., Frensing, T., & Reichl, U.Elucidating bottlenecks in influenza virus replication to optimize vaccine productionPresented at: International Conference on the Systems Biology of Human DiseaseHeidelberg, Germany, May 2, 2012.

Heldt, F. S., Frensing, T., & Reichl, U.Elucidating the dynamics of influenza virus replication by mathematical modelingPresented at: 22nd Annual Meeting of the Society for VirologyEssen, Germany, March 14, 2012.

Heldt, F. S., Frensing, T., & Reichl, U.Mechanistic model of influenza virus replication elucidates the intracellular dynamics and control of viral RNA synthesisPresented at: 12th International Conference on Systems BiologyHeidelberg/Mannheim, Germany, August 28, 2011.

Heldt, F. S. & Reichl, U.Modelling influenza virus infection dynamics in cell culture-based vaccine productionPresented at: 11th International Conference on Systems BiologyEdinburgh, Scotland, October 11, 2010.

Heldt, F. S. & Reichl, U.Multiscale modeling of influenza virus infection dynamics in cell culture-based vaccine productionPresented at: International Conference on Systems Biology of Human DiseaseBoston, USA, June 16, 2010.

Heldt, S. (2015)Mathematical Models of Influenza A Virus Infection: From Intracellular Replication to Virus Growth in Cell PopulationsPhD Thesis, Otto-von-Guericke Universität, Magdeburgdoi: 10.25673/4197.

Heldt, S. (2009)A Mathematical Model of Protein Translation and the Competition for Rare Cellular Resources in Response to Amino Acid StarvationDiploma Thesis, Otto-von-Guericke Universität, Magdeburg.