Publications of Alexander Rath
All genres
Journal Article (8)
2020
Journal Article
Rodrigues Correia Ramos, J., Rath, A., Genzel, Y., , & Reichl, U. (2020)A dynamic model linking cell growth to intracellular metabolism and extracellular by‐product accumulationBiotechnology and Bioengineering, 117 (5), 1533–1553doi: 10.1002/bit.27288.
2016
Journal Article
Rath, A., Reichl, U., , , , , & (2016)Early changes in the metabolic profile of activated CD8+ T cellsBMC Biology, 17 (1), 28doi: 10.1186/s12860-016-0104-x.
, 2014
Journal Article
Rath, A., Rehberg, M., Janke, R., Genzel, Y., , , , , & Reichl, U. (2014)The influence of cell growth and enzyme activity changes on intracellular metabolite dynamics in AGE1.HN.AAT cellsJournal of Biotechnology, 178, 43–53doi: 10.1016/j.jbiotec.2014.03.012.
Journal Article
Rehberg, M., Rath, A., Ritter, J., Genzel, Y., & Reichl, U. (2014)Changes in intracellular metabolite pools during growth of adherent MDCK cells in two different mediaApplied Microbiology and Biotechnology, 98 (1), 385–397doi: 10.1007/s00253-013-5329-4.
2013
Journal Article
Borchers, S., Freund, S., Rath, A., , Reichl, U., & (2013)Identification of Growth Phases and Influencing Factors in Cultivations with AGE1.HN Cells Using Set-Based MethodsPLoS One, 8 (8), e68124doi: 10.1371/journal.pone.0068124.
Journal Article
Freund, S., Rath, A., , , , , , , , , , , & Reichl, U. (2013)Batch-to-batch variability of two human designer cell lines - AGE1.HN and AGE1.HN.AAT - carried out by different laboratories under defined culture conditions using a mathematical modelEngineering in Life Sciences, 13 (6), 580–592doi: 10.1002/elsc.201200111.
2012
Journal Article
Rath, A., Freund, S., Reichl, U., , , , , , & (2012)Evaluation of criteria for bioreactor comparison and operation standardization for mammalian cell cultureEngineering in Life Sciences, 12 (5), 518–528doi: 10.1002/elsc.201100163.
, , , , , 2009
Journal Article
Lohr, V., Rath, A., Genzel, Y., , , & Reichl, U. (2009)New avian suspension cell lines provide production of influenza virus and MVA in serum-free media: studies on growth, metabolism and virus propagationVaccine, 27 (36), 4975–4982doi: 10.1016/j.vaccine.2009.05.083.
Conference Paper (1)
2012
Conference Paper
Lohr, V., Rath, A., , , Genzel, Y., & Reichl, U. (2012)Avian Designer Cells AGE1.CR as Candidates for MVA and Influenza Vaccine ProductionIn: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), 615–631doi: 10.1007/978-94-007-0884-6_102.
Meeting Abstract (3)
2011
Meeting Abstract
Rath, A., Reichl, U., , , , , , & (2011)Criteria for bioreactor comparison and operation standardisation during process development for mammalian cell cultureIn: BMC Proceedings, P47doi: 10.1186/1753-6561-5-S8-P47.
, , , ,
Meeting Abstract
Rath, A., , , , , Reichl, U., & (2011)Characterization of the human AGE1.HN cell line: a systems biology approachIn: BMC Proceedings, P78doi: 10.1186/1753-6561-5-S8-P78.
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Meeting Abstract
Rath, A., , , , , , Reichl, U., , , & (2011)Characterisation of cultivation of the human cell line AGE1.HN.AATIn: BMC Proceedings, P87doi: 10.1186/1753-6561-5-S8-P87.
, , , Talk (3)
2012
Talk
Rath, A., , , Janke, R., Genzel, Y., , , & Reichl, U.Insights into mammalian energy metabolism: connecting intracellular metabolites and maximum enzyme activitiesPresented at: GVC/DECHEMA Vortrags- und Diskussionstagung - Biopharmazeutische ProduktionFreiburg, May 14, 2012.
2009
Talk
Lohr, V., Rath, A., , , Genzel, Y., & Reichl, U.Avian designer cells AGE1.CR: possible candidates for MVA and influenza vaccine production?Presented at: 21st ESACT MeetingDublin, Ireland, June 7, 2009.
2008
Talk
Rath, A., Lohr, V., Genzel, Y., Schwarzer, J., Rapp, E., , , & Reichl, U.Influenza and modified vaccinia Ankara (MVA) production in avian designer cellsPresented at: BioperspectivesHannover, Germany, October 9, 2008.
Poster (11)
2016
Poster
Rodrigues Correia Ramos, J., Rath, A., Genzel, Y., , , & Reichl, U.A Dynamic Model of Growth and Metabolism of AGE1.HN Suspension CellsPresented at: 6th IFAC Conference on Foundations of Systems Biology in Engineering (FOSBE)Magdeburg, Germany, October 9, 2016.
2013
Poster
Blechert, A.-K., Rath, A., Sann, H., , , Genzel, Y., & Reichl, U.Towards an analytical platform for metabolic studies in adherent and suspension cells: intracellular metabolite concentrations and maximum enzyme activitiesPresented at: 23rd ESACT MeetingLille, France, June 23, 2013.
2012
Poster
Freund, S., Rath, A., , , & Reichl, U.Metabolic Flux Analysis of AAT Production in AGE1.HN.AAT Cells under Different Cultivation ConditionsPresented at: ESBES - 9 th European Symposium on Biochemical Engineering ScienceIstanbul, September 24, 2012.
Poster
Freund, S., Rath, A., , , & Reichl, U.Comparison of the productivity of a new human cell line in different steady states of continuous cultivations using MFAPresented at: Metabolic Engineering IXBiarritz, France, June 3, 2012.
2011
Poster
Freund, S., Rath, A., , , & Reichl, U.AGE1.HN.AAT - growth of a human cell line in glucose excess and limitation: comparison of different metabolic states via stationary metabolic flux analysisPresented at: 22nd ESACT MeetingVienna, Austria, May 15, 2011.