Publications of M. Wolff

Wolff, M., Siewert, C., Lehmann, S., Hansen, S. P., Djurup, R., Faber, R., & Reichl, U. (2010)Capturing of Cell Culture-Derived Modified Vaccinia Ankara Virus by Ion Exchange and Pseudo-Affinity Membrane AdsorbersBiotechnology and Bioengineering, 105 (4), 761–769doi: 10.1002/bit.22595.

Opitz, L., Hohlweg, J., Reichl, U., & Wolff, M. W. (2009)Purification of cell culture-derived influenza virus A/Puerto Rico/8/34 by membrane-based immobilized metal affinity chromatographyJournal of Virological Methods, 161 (2), 312–316doi: 10.1016/j.jviromet.2009.06.025.

Opitz, L., Lehmann, S., Reichl, U., & Wolff, M. W. (2009)Sulfated membrane adsorbers for economic pseudo-affinity capture of influenza virus particlesBiotechnology and Bioengineering, 103 (6), 1144–1154doi: 10.1002/bit.22345.

Opitz, L., Zimmermann, A., Lehmann, S., Genzel, Y., Lübben, H., Reichl, U., & Wolff, M. W. (2008)Capture of cell culture-derived influenza virus by lectins: strain independent, but host cell dependentJournal of Virological Methods, 154 (1-2), 61–68doi: 10.1016/j.jviromet.2008.09.004.

Wolff, M. W. & Reichl, U. (2008)Downstream Processing: From egg to cell culture-derived influenza virus particlesChemical Engineering and Technology, 31 (6), 846–857doi: 10.1002/ceat.200800118.

Bandaru, K. S. V. S. R., Keßler, L. C., Wolff, M. W., Reichl, U., Seidel-Morgenstern, A., & Pushpavanam, S. (2007)Hydrodynamic characteristics and expansion behavior of beds containing single and binary-mixtures of particlesIndustrial and Engineering Chemistry Research, 46 (13), 4686–4694doi: 10.1021/ie061580x.

Kalbfuss, B., Genzel, Y., Wolff, M. W., Zimmermann, A., Morenweiser, R., & Reichl, U. (2007)Harvesting and concentration of human influenza A virus produced in serum-free mammalian cell culture for the production of vaccinesBiotechnology and Bioengineering, 97 (1), 73–85doi: 10.1002/bit.21139.

Kalbfuss, B., Wolff, M. W., Geisler, L., Tappe, A., Wickramasinghe, R., Thom, V., & Reichl, U. (2007)Direct capture of influenza A virus from cell culture supernatant with Sartobind anion-exchange membrane adsorbersJournal of Membrane Science, 299, 251–260doi: 10.1016/j.memsci.2007.04.048.

Kalbfuss, B., Wolff, M. W., Morenweiser, R., & Reichl, U. (2007)Purification of cell culture-derived human influenza A virus by size-exclusion and anion-exchange chromatographyBiotechnology and Bioengineering, 96, 932–944doi: 10.1002/bit.21109.

Opitz, L., Lehmann, S., Zimmermann, A., Reichl, U., & Wolff, M. W. (2007)Impact of adsorbents selection on affinity purification efficiency of cell culture derived human Influenza virusesJournal of Biotechnology, 131 (3), 309–317doi: 10.1016/j.jbiotec.2007.07.723.

Opitz, L., Salaklang, J., Büttner, H., Reichl, U., & Wolff, M. W. (2007)Lectin-affinity chromatography for downstream processing of MDCK cell culture derived human influenza A virusesVaccine, 25 (5), 939–947doi: 10.1016/j.vaccine.2006.08.043.

Hoffmann, D., Leber, J., Loewe, D., Lothert, K., Oppermann, T., Zitzmann, J., Weidner, T., Salzig, D., Wolff, M. W., & Czermak, P. (2019)Purification of New Biologicals Using Membrane-Based ProcessesCurrent Trends and Future Developments on (Bio-) Membranes123–150Elsevierdoi: 10.1016/B978-0-12-813606-5.00005-1.

Kröber, T., Wolff, M. W., Lehmann, S., Zimmermann, A., & Reichl, U. (2012)Accounting for the Entire Influenza Hemagglutinin during a Flu Vaccine Production ProcessIn: ESACT - Proceedings of the 21st Annual meeting of the European Society for animal cell technology (ESACT), 685–689doi: 10.1007/978-94-007-0884-6_108.

Marichal-Gallardo, P., Genzel, Y., Börner, K., Grimm, D., Wolff, M. W., & Reichl, U. (2019)A single-use chromatographic purification platform for viral gene transfer vectors & viral vaccinesIn: Proceedings Advancing Manufacture of Cell and Gene Therapies VI, 92.

Fortuna, A. R., Taft, F., Villain, L., Wolff, M. W., & Reichl, U. (2018)Continuous purification of cell culture-derived influenza A virus particles through pseudo- affinity membrane chromatographyIn: Vaccine Technology VII, 124.

Marichal-Gallardo, P., Fortuna, A. R., Genzel, Y., Wolff, M. W., & Reichl, U. (2018)Purifying viruses with a sheet of paper: Single-use steric exclusion chromatography as a capture platform for vaccine candidatesIn: Vaccine Technology VII, 128.

Peixoto, C., Carvalho, S. B., Carrondo, M. J. T., Alves , P. M., Fortuna, A. R., Reichl, U., & Wolff, M. W. (2018)Addressing the challenges of influenza virus-like particles purificationIn: Vaccine Technology VII, 57.

Taft, F., Köhler, R., Van Teeffelen, S., Fortuna, A. R., Wolff, M. W., Reichl, U., Villain, L., & Boulais, A. (2018)Influenza virus capture using membrane chromatography: Improving selectivity by matrix design and pseudo-affinity ligand interactionsIn: Vaccine Technology VII, 75.

Pieler, M., Frentzel, S., Bruder , D., Wolff, M. W., & Reichl, U. (2016)Pseudo-affinity purification and formulation of a cell-culture derived whole influenza virus vaccine using magnetic sulfated cellulose particlesIn: Vaccine Technology VI, 57.

Marichal-Gallardo, P., Genzel, Y., Börner, K., Grimm, D., Wolff, M. W., & Reichl, U.A single-use purification platform for viral vaccines & gene therapy vectorsPresented at: International Symposium on the Separation of Proteins, Peptides, and Polynucleotides (ISPPP) 2018Berlin, Germany, November 3, 2018.