Publications of Thomas Bissinger

Rodrigues Correia Ramos, J.; Bissinger, T.; Genzel, Y.; Reichl, U.: Impact of Influenza A Virus Infection on Growth and Metabolism of Suspension MDCK Cells Using a Dynamic Model. Metabolites 12 (3), 239 (2022)

Bissinger, T.; Wu, Y.; Marichal-Gallardo, P.; Riedel, D.; Liu, X.; Genzel, Y.; Tan, W.; Reichl, U.: Towards integrated production of an influenza A vaccine candidate with MDCK suspension cells. Biotechnology and Bioengineering 118 (10), pp. 3996 - 4013 (2021)

Wu, Y.; Bissinger, T.; Genzel, Y.; Liu, X.; Reichl, U.; Tan, W.-S.: High cell density perfusion process for high yield of influenza A virus production using MDCK suspension cells. Applied Microbiology and Biotechnology 105 (4), pp. 1421 - 1434 (2021)

Bissinger, T.; Fritsch, J.; Mihut, A. N.; Wu, Y.; Liu, X.; Genzel, Y.; Tan, W.-S.; Reichl, U.: Semi-perfusion cultures of suspension MDCK cells enable high cell concentrations and efficient influenza A virus production. Vaccine 37 (47), pp. 7003 - 7010 (2019)

Koch, S.; Kohrs, F.; Lahmann, P.; Bissinger, T.; Wendschuh, S.; Benndorf, D.; Reichl, U.; Klamt, S.: RedCom: A strategy for reduced metabolic modeling of complex microbial communities and its application for analyzing experimental datasets from anaerobic digestion. PLoS Computational Biology 15 (2), e1006759 (2019)

Kohrs, F.; Heyer, R.; Bissinger, T.; Kottler, R.; Schallert, K.; Püttker, S.; Behne, A.; Rapp, E.; Benndorf, D.; Reichl, U.: Proteotyping of laboratory-scale biogas plants reveals multiple steady-states in community composition. Anaerobe 46, pp. 56 - 68 (2017)

Nikolay, A.; Bissinger, T.; Gränicher, G.; Wu, Y.; Genzel, Y.; Reichl, U.: Perfusion Control for High Cell Density Cultivation and Viral Vaccine Production. In: Animal Cell Biotechnology, pp. 141 - 168 (Ed. Pörtner, R.). Humana, New York (2020)

Bissinger, T.; Reichl, U.; Genzel, Y.; Wu, Y.; Liu, X.; Tan, W.-S.: Highly efficient influenza virus production: A MDCK-based high-cell-density process. In Vaccine Technology VII, 13. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)

Wu, Y.; Liu, X.; Tan, W.-S.; Bissinger, T.; Genzel, Y.; Reichl, U.: Efficient influenza vaccine manufacturing: Single MDCK suspension cells in chemically defined medium. In Vaccine Technology VII, 5. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)

Kohrs, F.; Heyer, R.; Benndorf, D.; Bissinger, T.; Kottler, R.; Fronk, K.; Rapp, E.; Reichl, U.: Kultivierung und Metaproteomanalyse anaerober mikrobieller Gemeinschaften. 23. SIMBA-Treffen, Havelberg, Germany (2016)

Rodrigues Correia Ramos, J.; Bissinger, T.; Genzel, Y.; Reichl, U.: A Dynamic Model for Cell Growth, Metabolism & Virus Production of MDCK Suspension Cells. YCOPE 2019, Magdeburg, Germany (2019)

Bissinger, T.; Rodrigues Correia Ramos, J.; Ringeisen, J.; Genzel, Y.; Reichl, U.: Dynamics of intracellular metabolite pools in MDCK suspension cells during cell growth and influenza virus infection. Cell Culture Engineering XVI, Tampa, Florida, USA (2018)

Bissinger, T.; Wu, Y.; Genzel, Y.; Liu, X.; Wen-Song, T.; Reichl, U.: Efficient influenza virus production: a MDCK-based high-cell-density process. Vaccine Technology VII, Mont Tremblant, Canada (2018)

Bissinger, T.; Rodrigues Correia Ramos, J.; Ringeisen, J.; Genzel, Y.; Reichl, U.: Intracellular Metabolic Pool Dynamics in MDCK Suspension Cells during Growth and Influenza Virus Infection. 25th ESACT Meeting, Lausanne, Switzerland (2017)

Kohrs, F.; Heyer, R.; Bissinger, T.; Kottler, R.; Schallert, K.; Püttker, S.; Behne, A.; Rapp, E.; Benndorf, D.; Reichl, U.: Proteotyping of microbial communities from laboratory-scale biogas plants reveals multiple steady-states. 14th Symposium on Bacterial Genetics and Ecology (BAGECO 14), Aberdeen, Scotland (2017)

Bissinger, T.; Schleuß, T.; Thom, V.; Wolff, M.; Reichl, U.: Separation of Enterovirus 71 Virus Like Particles from Baculovirus by Crossflow Filtration. ESACT 2015, Barcelona, Spain (2015)

Wolff, M. W.; Meininger, M.; Bissinger, T.; Djurup, R.; Villain, L.; Schleuß, T.; Thom, V.; Cardosa, J.; Reichl, U.: Development of a Purification Strategy for Enterovirus 71 Like Particles for Vaccine Production. The Recovery of Biological Products XVI Conference, Rostock, Germany (2014)

Bissinger, T.: Evaluation of MDCK suspension cell lines for influenza A virus production: media, metabolism, and process conditions. Dissertation, Otto-von-Guericke-Universität, Magdeburg (2020)

Bissinger, T.: Separation of Enterovirus 71 Virus Like Particles from Baculovirus by Cross Flow Filtration. Diploma, Universität Stuttgart, Stuttgart (2013)