Publications of Sascha Young Kupke

Pelz, L.; Dogra, T.; Boehme, J.D.; Marichal-Gallardo, P.; Hein, M. D.; Genzel, Y.; Bruder, D.; Kupke, S. Y.; Reichl, U.: A Scalable High-Yield Process for Production of Influenza A Virus Defective Interfering Particles and In Vivo Studies. Himmelfahrtstagung on Bioprocess Engineering 2023, Weimar (Germany) (2023)

Pelz, L.; Dogra, T.; Boehme, J.D.; Marichal-Gallardo, P.; Hein, M. D.; Genzel, Y.; Bruder, D.; Kupke, S. Y.; Reichl, U.: Influenza A Virus Chimeric OP7 Defective Interfering Particles: Cell Culture-based Production and In Vivo Antiviral Efficacy. 32^nd Annual Meeting of the Society for Virology (GFV), Ulm (Germany) (2023)

Piasecka, J.; Rüdiger, D.; Kupke, S. Y.; Reichl, U.: Reduced transcription of the mutated genomic segment 7 of the novel “OP7” influenza defective interfering particle intended for use as an antiviral. 8^th European Congress of Virology, Gdańsk (Poland) (2023)

Piasecka, J.; Rüdiger, D.; Kupke, S. Y.; Reichl, U.: Promoter mutations in novel “OP7” influenza defective interfering particle severely reduce transcription of its genomic segment 7. 32^nd Annual Meeting of the Society for Virology (GfV), Ulm (Germany) (2023)

Piasecka, J.; Rüdiger, D.; Kupke, S. Y.; Reichl, U.: Promoter mutations in the novel “OP7” influenza defective interfering particle intended for use as antiviral. 17^th Vaccine Congress, Glasgow (Scotland) (2023)

Dogra, T.; Pelz, L.; Marc, H.; Rüdiger, D.; Boehme, J.; Bruder, D.; Kupke, S. Y.; Reichl, U.: Reverse genetics for Influenza A virus to generate genetically engineered defective interfering particles for antiviral treatment and vaccination. 27th ESACT Meeting, Lisbon (Portugal) (2022)

Hein, M.; Chawla, A.; Arora , P.; Cattaneo, M.; Winkler, M.; Pöhlmann, S.; Genzel, Y.; Kupke, S. Y.; Reichl, U.: Production of influenza A virus-derived defective interfering particles for antiviral therapy in a high cell density perfusion cultivation. 27th ESACT Meeting, Lisbon (Portugal) (2022)

Küchler, J.; Püttker, S.; Lahmann, P.; Genzel, Y.; Kupke, S. Y.; Benndorf, D.; Reichl, U.: Absolute quantification of viral proteins during single-round replication of MDCK suspension cells. Proteomic Forum 2022, Leipzig (Germany) (2022)

Kupke, S. Y.; Hein, M.D.; Bdeir, N.; Rand, U.; Marichal-Gallardo, P.; Cicin-Sain, L.; Bruder, D.; Pöhlmann, S.; Schughart, K.; Reichl, U.: Influenza A Virus Defective Interfering Particles for Antiviral Treatment of the Influenza Disease and COVID-19. 31st Annual Meeting of the Society for Virology, online (2022)

Kupke, S. Y.; Hein, M.; Bdeir, N.; Rand, U.; Marichal-Gallardo, P.; Cicin-Sain, L.; Bruder, D.; Pöhlmann, S.; Schughart, K.; Reichl, U.: Influenza A Virus Defective Interfering Particles for Antiviral Treatment of the Influenza Disease and COVID-19. Vaccine Technology VIII, Sitges (Spain) (2022)

Pelz, L.; Rüdiger, D.; Dogra, T.; Alnaji, F.G.; Genzel, Y.; Brooke, C.B.; Kupke, S. Y.; Reichl, U.: Long-Term Propagation of Influenza A Virus and Its Defective Interfering Particles: Analyzing Dynamic Competition to Select Antiviral Candidates. Vaccine Technology VIII, Sitges (Spain) (2022)

Pelz, L.; Rüdiger, D.; Dogra, T.; Alnaji, F. G.; Genzel, Y.; Brooke, C. B.; Kupke, S. Y.; Reichl, U.: Semi-Continuous propagation of Influenza A virus and its defective interfering particles: Analyzing the dynamic competition to select antiviral candidates. 27th ESACT Meeting, Lisbon (Portugal) (2022)

Pelz, L.; Rüdiger, D.; Alnaji, F. G.; Genzel, Y.; Brooke, C. B.; Kupke, S. Y.; Reichl, U.: Semi-continuous propagation of influenza A virus and its defective interfering particles - analyzing the dynamic competition to select antiviral candidates. 30th Annual Meeting of the Society for Virology, online (2021)

Kupke, S. Y.; Hein, M. D.; Kollmus, H.; Marichal-Gallardo, P.; Schughart, K.; Reichl, U.: The novel influenza A virus defective interfering particle "OP7" as an antiviral agent: discovery, production, and animal trials. The seventh ESWI Influenza Conference, Virtual Meeting (2020)

Kupke, S. Y.; Riedel, D.; Frensing, T.; Zmora, P.; Reichl, U.: A novel type of defective interfering particle for antiviral therapy. 26th ESACT Meeting, Copenhagen, Denmark (2019)

Rüdiger, D.; Laske, T.; Kupke, S. Y.; Reichl, U.: A multiscale model of defective interfering particle replication. FOSBE 2019, Valencia, Spain (2019)

Rüdiger, D.; Kupke, S. Y.; Reichl, U.: A multiscale model of influenza A virus replication covering highly different infection conditions in cell cultures. Foundations of Systems Biology in Engineering - 7th FOSBE 2018, Oak Brook, Illinois, USA (2018)

Rüdiger, D.; Heldt, S.; Kupke, S. Y.; Reichl, U.: Stochastic multiscale modeling of influenza virus production in cell cultures. Poster presented at 6th IFAC Conference on Foundations of Systems Biology in Engineering. 6th IFAC Conference on Foundations of Systems Biology in Engineering (FOSBE), Magdeburg, Germany (2016)

Rüdiger, D.; Heldt, S.; Kupke, S. Y.; Reichl, U.: Stochastic multiscale modeling of influenza virus production in cell cultures. 6th IFAC Conference on Foundations of Systems Biology in Engineering (FOSBE), Magdeburg, Germany (2016)

Kupke, S. Y.; Heldt, F.S.; Frensing, T.; Reichl, U.: Single Cell Analysis of Influenza A Virus-infected Cells for the Optimization of Cell Culture-based Vaccine Manufacturing Processes. ESACT 2015, Barcelona, Spain (2015)