Publications of Former Research Groups

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Journal Article (7)

  1. Journal Article
    Laske, T.; Heldt, S.; Hoffmann, H.; Frensing, T.; Reichl, U.: Reprint of “Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs. Virus Research 218, pp. 86 - 95 (2016)
  2. Journal Article
    Laske, T.; Heldt, F. S.; Hoffmann, H.; Frensing, T.; Reichl, U.: Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs. Virus Research 213, pp. 90 - 99 (2016)
  3. Journal Article
    Heldt, F. S.; Kupke, S. Y.; Dorl, S.; Frensing, T.; Reichl, U.: Single-cell analysis and stochastic modelling unveil large cell-to-cell variability in influenza A virus infection. Nature Communications 6, 8938 (2015)
  4. Journal Article
    Frensing, T.; Heldt, S.; Pflugmacher, A.; Behrendt, I.; Jordan, I.; Flockerzi, D.; Genzel, Y.; Reichl, U.: Continuous Influenza Virus Production in Cell Culture Shows a Periodic Accumulation of Defective Interfering Particles. PLoS One 8 (9), p. e72288 (2013)
  5. Journal Article
    Heldt, S.; Frensing, T.; Pflugmacher, A.; Gröpler, R.; Peschel, B.; Reichl, U.: Multiscale Modeling of Influenza A Virus Infection Supports the Development of Direct-Acting Antivirals. PLoS Computational Biology 9 (11), p. e1003372 (2013)
  6. Journal Article
    Heldt, F. S.; Frensing, T.; Reichl, U.: Modeling the intracellular dynamics of influenza virus replication to understand the control of viral RNA synthesis. Journal of Virology 86 (15), pp. 7806 - 7817 (2012)
  7. Journal Article
    Vester, D.; Pflugmacher, A.; Hoffmann, D.; Seitz, C.; Heldt, S.; Bettenbrock, K.; Genzel, Y.; Reichl, U.: Real-time RT-qPCR assay for the analysis of human influenza A virus transcription and replication dynamics. Journal of Virological Methods 168 (1-2), pp. 63 - 71 (2010)

Talk (9)

  1. Talk
    Kupke, S. Y.; Heldt, S.; Frensing, T.; Reichl, U.: Single-Cell Analysis of Influenza A Virus-Infected Cells. 26th Annual Meeting of the Society for Virology, Münster, Germany (2016)
  2. Talk
    Kupke, S. Y.; Heldt, S.; Frensing, T.; Reichl, U.: Heterogeneity in Influenza A Virus Infection Unveiled by Single-Cell Analysis and Stochastic Mathemeatical Modeling. Single Cell Technologies 2016, Frankfurt/Main (2016)
  3. Talk
    Kupke, S. Y.; Heldt, S.; Frensing, T.; Reichl, U.: Single-Cell Analysis of Influenza A Virus-Infected Cells for the Optimization of Cell Culture-Based Vaccine Production. Vaccine Technology VI, Albufeira, Portugal (2016)
  4. Talk
    Laske, T.; Heldt, F. S.; Frensing, T.; Reichl, U.: Analyzing the dynamics of influenza A virus replication in the presence of defective interfering RNAs. 2nd Workshop on Virus Dynamics, Toronto, Ontario, Canada (2015)
  5. Talk
    Heldt, S.; Frensing, T.; Reichl, U.: The multiscale nature of influenza A virus infection and its implications for modeling antiviral therapy. The Joint Annual Meeting of the Japanese Society for Mathematical Biology and the Society for Mathematical Biology, Osaka, Japan (2014)
  6. Talk
    Heldt, S.; Isken, B.; Pflugmacher, A.; Frensing, T.; Reichl, U.: Multi-scale modeling of influenza virus infection elucidates the performance of antivirals. 1st Workshop on Virus Dynamics (DECHEMA), Frankfurt/Main, Germany (2013)
  7. Talk
    Heldt, S.; Peschel, B.; Frensing, T.; Reichl, U.: Multiscale modeling of influenza virus infection supports the development of antiviral drugs. 14th International Conference on Systems Biology , Copenhagen (Denmark) (2013)
  8. Talk
    Heldt, F. S.; Frensing, T.; Reichl, U.: Elucidating bottlenecks in influenza virus replication to optimize vaccine production. International Conference on the Systems Biology of Human Disease, Heidelberg, Germany (2012)
  9. Talk
    Heldt, F. S.; Reichl, U.: Understanding the dynamics of intracellular virus replication - How does Influenza control its RNA and protein synthesis? 4th ESWI Influenza Conference, Malta (2011)

Poster (21)

  1. Poster
    Laske, T.; Heldt, F. S.; Hoffmann, H.; Frensing, T.; Reichl, U.: Modeling the intracellular replication of influenza A virus in the presence of defective interfering RNAs. 26th Annual Meeting of the Society for Virology, Münster, Germany (2016)
  2. Poster
    Rüdiger, D.; Heldt, S.; Kupke, S. Y.; Reichl, U.: Stochastic multiscale modeling of influenza virus production in cell cultures. Poster presented at 6th IFAC Conference on Foundations of Systems Biology in Engineering. 6th IFAC Conference on Foundations of Systems Biology in Engineering (FOSBE), Magdeburg, Germany (2016)
  3. Poster
    Kupke, S. Y.; Heldt, F.S.; Frensing, T.; Reichl, U.: Single Cell Analysis of Influenza A Virus-infected Cells for the Optimization of Cell Culture-based Vaccine Manufacturing Processes. ESACT 2015, Barcelona, Spain (2015)
  4. Poster
    Laske, T.; Heldt, F. S.; Frensing, T.; Reichl, U.: Analyzing the intracellular replication of influenza A virus in the presence of defective interfering RNAs. International Conference on Systems Biology of Human Disease (SBHD), Heidelberg, Germany (2015)
 
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