Publications

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Journal Article (3)

  1. Journal Article
    Nikolay, A.; Léon, A.; Schwamborn, K.; Genzel, Y.; Reichl, U.: Process intensification of EB66 ® cell cultivations leads to high-yield yellow fever and Zika virus production. Applied Microbiology and Biotechnology 102 (20), pp. 8725 - 8737 (2018)
  2. Journal Article
    Nikolay, A.; Casthilho, L. R.; Reichl, U.; Genzel, Y.: Propagation of Brazilian Zika virus strains in static and suspension cultures using Vero and BHK cells. Vaccine 36 (28), pp. 3140 - 3145 (2018)
  3. Journal Article
    Gallo Ramirez, L. E.; Nikolay, A.; Genzel, Y.; Reichl, U.: Bioreactor concepts for cell culture-based viral vaccine production. Expert Review of Vaccines 14 (9), pp. 1181 - 1191 (2015)

Meeting Abstract (1)

  1. Meeting Abstract
    Nikolay, A.; Genzel, Y.; Schwamborn, K.; Leon, A.; Reichl, U.: Flavivirus production in perfusion processes using the EB66® cell line. In Vaccine Technology VII, 80. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)

Talk (4)

  1. Talk
    Nikolay, A.: Stable animal cell growth in perfusion processes: Using on-line permittivity sensors to control cell-specific perfusion rates. 5th BioProScale Symposium, Berlin, Germany (2018)
  2. Talk
    Nikolay, A.: Cell-culture-based perfusion processes for Flavivirus production. 5th Laupheim Biotech Days, Laupheim, Germany (2018)
  3. Talk
    Nikolay, A.; Genzel, Y.; Reichl, U.: Process intensification – Yellow fever virus and Zika virus production in suspension cells. 13th PEACe Conference: Conference on Protein Expression in Animal Cells, Valencia, Spain (2017)
  4. Talk
    Vazquez-Ramirez, D.; Nikolay, A.; Behrendt, I.; Jordan, I.; Bürgin, T.; Genzel, Y.; Reichl, U.: High-cell-density cultivations by hollow fiber-based perfusion for intensified viral vaccine production. VII SLATCC meeting , Cocoyoc, Morelos, Mexico (2016)

Poster (9)

  1. Poster
    Nikolay, A.: CCE: The EB66 (R) Cell line for Yellow Fever Vaccine procustion at high cell concentrations. Cell Culture Engineering XVI, Tampa, Florida, USA (2018)
  2. Poster
    Nikolay, A.: Flavivirus production in perfusion processes using the EB66 (R) Cell line. Vaccine Technology VII, Mont Tremblant, Canada (2018)
  3. Poster
    Nikolay, A.; Castilho, L.; Genzel, Y.; Reichl, U.: Process intensification of yellow fever virus and Zika virus production by perfusion bioreactors. 25th ESACT Meeting, Lausanne, Switzerland (2017)
  4. Poster
    Nikolay, A.; Castilho, L.; Genzel, Y.; Reichl, U.: Production of yellow fever virus and Zika virus in perfusion bioreactors. DECHEMA Himmelfahrtstagung "Models for Developing and Optimising Biotech Production", Neu-Ulm, Germany (2017)
  5. Poster
    Nikolay, A.; Castilho, L.; Tanuri, A.; Reichl, U.; Genzel, Y.: Propagation of Brazilian Zika virus strains in static, microcarrier-based and suspension cultures using BHK and Vero cells. 1st ESACT Frontiers Retreat 2016, Lyon, France (2016)
  6. Poster
    Nikolay, A.; Castilho, L.; Tanuri, A.; Reichl, U.; Genzel, Y.: Propagation of Brazilian Zika virus strains in static, microcarrier-based and suspension cultures using BHK and Vero cells. Vaccine Technology VI, Albufeira, Portugal (2016)
  7. Poster
    Nikolay, A.; Herrmann, K.; Genzel, Y.; Reichl, U.: Evaluation of producer cell lines for yellow fever virus production in up to 1 L bioreactor scale. Vaccine Technology VI, Albufeira, Portugal (2016)
  8. Poster
    Vazquez-Ramirez, D.; Nikolay, A.; Genzel, Y.; Reichl, U.: On-line monitoring tools in batch and (semi-)perfusion cultivations for vaccine production. 4th BioProScale Symposium "Bioprocess intensification through Process Analytical Technology (PAT) and Quality by Design (QbD)", Berlin (2016)
  9. Poster
    Nikolay, A.; Scharfenberg, K.; Patel, P.; Niedrig, M.; Genzel, Y.; Reichl, U.: Towards yellow fever 17D virus production in Vero suspension cells. ESACT, Barcelona (2015)

Thesis - Master (1)

  1. Thesis - Master
    Nikolay, A.: Investigation of hollow fiber based high cell density cultivations of BHK-21 cells for continuous bovine respiratory syncytial virus vaccine manufacturing. Master, 87 pp., Technische Universität, Braunschweig (2014)
 
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