Publications of Lars Pelz

Göbel, S.; Pelz, L.; Silva, C. A. T.; Brühlmann, B.; Hill, C.; Altomonte, J.; Kamen, A.; Reichl, U.; Genzel, Y.: Production of recombinant vesicular stomatitis virus-based vectors by tangential flow depth filtration. Applied Microbiology and Biotechnology 108 (1), 240 (2024)

Pelz, L.; Dogra, T.; Marichal-Gallardo, P.; Hein, M. D.; Hemissi, G.; Kupke, S. Y.; Genzel, Y.; Reichl, U.: Production of antiviral “OP7 chimera” defective interfering particles free of infectious virus. Applied Microbiology and Biotechnology 108, 97 (2024)

Dogra, T.; Pelz, L.; Boehme, J. D.; Küchler, J.; Kershaw, O.; Marichal-Gallardo, P.; Baelkner, M.; Hein, M. D.; Gruber, A. D.; Benndorf, D. et al.; Genzel, Y.; Bruder, D.; Kupke, S. Y.; Reichl, U.: Generation of “OP7 chimera” defective interfering influenza A particle preparations free of infectious virus that show antiviral efficacy in mice. Scientific Reports 13, 20936 (2023)

Pelz, L.; Piagnani, E.; Marsall, P.; Wynserski, N.; Hein, M. D.; Marichal-Gallardo, P.; Kupke, S. Y.; Reichl, U.: Broad-Spectrum Antiviral Activity of Influenza A Defective Interfering Particles against Respiratory Syncytial, Yellow Fever, and Zika Virus Replication In Vitro. Viruses 15 (9), 1872 (2023)

Pelz, L.; Rüdiger, D.; Dogra, T.; Alnaji, F. G.; Genzel, Y.; Brooke, C. B.; Kupke, S. Y.; Reichl, U.: Semi-continuous propagation of influenza A virus and its defective interfering particles: analyzing the dynamic competition to select candidates for antiviral therapy. Journal of Virology 95 (24), e01174-21 (2021)

Rüdiger, D.; Pelz, L.; Hein, M. D.; Kupke, S. Y.; Reichl, U.: Multiscale model of defective interfering particle replication for influenza A virus infection in animal cell culture. PLoS Computational Biology 17, e1009357 (2021)

Göbel, S.; Pelz, L.; Reichl, U.; Genzel, Y.: Upstream processing for viral vaccines - Process intensification. In: Bioprocessing of Viral Vaccines, pp. 137 - 174 (Eds. Kamen, A.; Cervera, L.). CRC Press, Boca Raton (2023)

Pelz, L.; Göbel, S.; Jaen , K.; Reichl, U.; Genzel, Y.: Upstream processing for viral vaccines – General aspects. In: Bioprocessing of Viral Vaccines, pp. 79 - 136 (Eds. Kamen , A.; Cervera , L.). CRC Press, Boca Raton (2023)

Bälkner, M.; Jeron, A.; Volckmar, J.; Pelz, L.; Dogra, T.; Kupke, S. Y.; Bruder, D.: Characterization of the local innate immune response after mucosal application of IAV Defective Interfering Particles. In European Journal of Immunology, 53 (2) Special Issue: SI Ed., P339. Joint Conference of the Société Française d'Immunologie (SFI) and the Deutsche Gesellschaft für Immunologie (DGfI), Strasbourg (France), September 26, 2023 - September 29, 2023. Wiley-VCH, Weinheim (2023)

Göbel, S.; Pelz, L.; Behrendt, I.; Prömmel, M.; Altomonte, J.; Anderlei, T.; Bürgin, T.; Genzel, Y.; Reichl, U.: Scale-Down of an Ortbital Shaken Bioreactor: High Cell Density Cultivation in Perfusion Mode and Virus production. In Proceedings Single-Use Technologies V: Building the Future, 40. Single-Use Technologies V: Building the Future, Marseille, France, March 20, 2022 - March 23, 2022. (2022)

Pelz, L.; Rüdiger, D.; Hein, M.; Böhme, J.; Bälkner, M.; Kershaw, O.; Marichal-Gallardo, P.; Gruber, A.; Genzel, Y.; Bruder, D. et al.; Kupke, S. Y.; Reichl, U.: Engineered defective interfering particles of influenza A virus for antiviral treatment. 33^rd Annual Meeting of the Society for Virology (GfV), Vienna (Austria) (2024)

Pelz, L.; Rüdiger, D.; Hein, M. D.; Böhme, J.; Bälkner, M.; Kershaw, O.; Marichal-Gallardo, P.; Gruber, A.; Genzel, Y.; Bruder, D. et al.; Kupke, S. Y.; Reichl, U.: Genetic engineering of Influenza A virus defective interfering particles towards improved antiviral efficacy and potential use as a live vaccine. Vaccine Technology IX, Los Cabos (Mexico) (2024)

Dogra, T.; Pelz, L.; Boehme, J. D.; Baelkner, M.; Kershaw, O.; Marichal-Gallardo, P.; Gruber, A. D.; Genzel, Y.; Bruder, D.; Kupke, S. Y. et al.; Reichl, U.: Genetically engineered defective interfering particles of influenza A virus for antiviral treatment and vaccination. 17^th Vaccine Congress, Glasgow (Scotland) (2023)

Dogra, T.; Pelz, L.; Rüdiger, D.; Kupke, S. Y.; Reichl, U.: Reverse genetics for Influenza a virus to generate genetically engineered defective interfering particles for antiviral treatment and vaccination. Vir-AI-DIP Workshop , Hamburg (Germany) (2023)

Göbel, S.; Jaén, K. E.; Pelz, L.; Reiter , M.; Altomonte, J.; Reichl, U.; Genzel, Y.: Intensifiying OSB processes for high titer virus production. 5^th large scale meeting: Orbital shaken bioreactors, Girona (Spain) (2023)

Kupke, S. Y.; Dogra, T.; Pelz, L.; Hein, M. D.; Ndeir, N.; Rand, U.; Boehme, J.; Baelkner, M.; Kershaw, O.; Winkler, M. et al.; Cicin-Sain, L.; Bruder, D.; Pöhlmann, S.; Reichl, U.: Influenza A virus defective interfering particles as antiviral agents. 32^nd Annual Meeting of the Society for Virology (GfV), Ulm (Germany) (2023)

Pelz, L.; Dogra, T.; Boehme, J.D.; Hein, M. D.; Marichal-Gallardo, P.; Genzel, Y.; Bruder, D.; Kupke, S. Y.; Reichl, U.: Influenza A virus OP7 defective interfering particles: Cell culture-based production and antiviral efficacy in vivo. Cell Culture Engineering (CCE) XVIII , Cancun (Mexico) (2023)

Pelz, L.; Genzel, Y.; Kupke, S. Y.; Reichl, U.: In-depth characterization and cell culture-based production of influenza A virus defective interfering particles. ACTIP fellowship session, Dublin (Ireland) (2023)

Pelz, L.; Rüdiger, D.; Dogra, T.; Alnaji, F. D.; Genzel, Y.; Brooke, C. B.; Kupke, S. Y.; Reichl, U.: Semi-continuous Propagation of Influenza A Virus and Its Defective Interfering Particles: Analyzing the Dynamic Competition To Select Candidates for Antiviral Therapy. Vir-AI-DIP Workshop, Hamburg (Germany) (2023)

Rüdiger, D.; Pelz, L.; Hein, M. D.; Kupke, S. Y.; Reichl, U.: Multiscale model of influenza A virus and defective interfering particle co-infection in animal cell culture. Vir-AI-DIP Workshop, Hamburg (Germany) (2023)