Publications of Alexander Nikolay

Journal Article (5)

2021
Journal Article
Pralow, A.; Nikolay, A.; Leon, A.; Genzel, Y.; Rapp, E.; Reichl, U.: Site-specific N-glycosylation analysis of animal cell culture-derived Zika virus proteins. Scientific Reports 11 (1), 5147 (2021)
2020
Journal Article
Nikolay, A.; de Grooth, J.; Genzel, Y.; Wood, J. A.; Reichl, U.: Virus harvesting in perfusion culture: Choosing the right typeof hollow fiber membrane. Biotechnology and Bioengineering 117 (10), pp. 3040 - 3052 (2020)
2018
Journal Article
Nikolay, A.; Casthilho, L. R.; Reichl, U.; Genzel, Y.: Propagation of Brazilian Zika virus strains in static and suspension cultures using Vero and BHK cells. Vaccine 36 (22), pp. 3140 - 3145 (2018)
Journal Article
Nikolay, A.; Léon, A.; Schwamborn, K.; Genzel, Y.; Reichl, U.: Process intensification of EB66 ® cell cultivations leads to high-yield yellow fever and Zika virus production. Applied Microbiology and Biotechnology 102 (20), pp. 8725 - 8737 (2018)
2015
Journal Article
Gallo Ramirez, L. E.; Nikolay, A.; Genzel, Y.; Reichl, U.: Bioreactor concepts for cell culture-based viral vaccine production. Expert Review of Vaccines 14 (9), pp. 1181 - 1191 (2015)

Book Chapter (1)

2020
Book Chapter
Nikolay, A.; Bissinger, T.; Gränicher, G.; Wu, Y.; Genzel, Y.; Reichl, U.: Perfusion Control for High Cell Density Cultivation and Viral Vaccine Production. In: Animal Cell Biotechnology, pp. 141 - 168 (Ed. Pörtner, R.). Humana, New York (2020)

Meeting Abstract (1)

2018
Meeting Abstract
Nikolay, A.; Genzel, Y.; Schwamborn, K.; Leon, A.; Reichl, U.: Flavivirus production in perfusion processes using the EB66® cell line. In Vaccine Technology VII, 80. Vaccine Technology VII, Mont Tremblant, Canada, June 17, 2018 - June 22, 2018. (2018)

Talk (8)

2020
Talk
Reichl, U.; Vazquez-Ramirez, D.; Tapia, F.; Nikolay, A.; Genzel, Y.: Cell Culture-based Viral Vaccines: Process Intensification and Monitoring. Plenarsitzung der Sächischen Akademie der Wissenschaften zu Leipzig, Leipzig, Germany (2020)
2019
Talk
Nikolay, A.; Tapia, F.; Marichal-Gallardo, P.; Pralow, A.; Hoffmann, M.; Rapp, E.; Genzel, Y.; Reichl, U.: Moderne Methoden der Impfstoffherstellung. Wissenschaft im Rathaus, Magdeburg, Germany (2019)
Talk
Nikolay, A.; Tapia, F.; Marichal-Gallardo, P.; Pralow, A.; Hoffmann, M.; Rapp, E.; Genzel, Y.; Reichl, U.: Cell Culture-based Viral Vaccines: Process Intensification and Monitoring. Cuba Symposium “Frontiers of Science”, Havanna, Cuba (2019)
Talk
Reichl, U.; Vazquez-Ramirez, D.; Tapia, F.; Nikolay, A.; Genzel, Y.; Rapp, E.: Process Intensification in Viral Vaccine Manufacturing. International Symposium on Pharmaceutical Engineering Research – SPhERe, Braunschweig, Germany (2019)
2018
Talk
Nikolay, A.: Stable animal cell growth in perfusion processes: Using on-line permittivity sensors to control cell-specific perfusion rates. 5th BioProScale Symposium, Berlin, Germany (2018)
Talk
Nikolay, A.: Cell-culture-based perfusion processes for Flavivirus production. 5th Laupheim Biotech Days, Laupheim, Germany (2018)
2017
Talk
Nikolay, A.; Genzel, Y.; Reichl, U.: Process intensification – Yellow fever virus and Zika virus production in suspension cells. 13th PEACe Conference: Conference on Protein Expression in Animal Cells, Valencia, Spain (2017)
2016
Talk
Vazquez-Ramirez, D.; Nikolay, A.; Behrendt, I.; Jordan, I.; Bürgin, T.; Genzel, Y.; Reichl, U.: High-cell-density cultivations by hollow fiber-based perfusion for intensified viral vaccine production. VII SLATCC meeting , Cocoyoc, Morelos, Mexico (2016)

Poster (9)

2018
Poster
Nikolay, A.: CCE: The EB66 (R) Cell line for Yellow Fever Vaccine procustion at high cell concentrations. Cell Culture Engineering XVI, Tampa, Florida, USA (2018)
Poster
Nikolay, A.: Flavivirus production in perfusion processes using the EB66 (R) Cell line. Vaccine Technology VII, Mont Tremblant, Canada (2018)
2017
Poster
Nikolay, A.; Castilho, L.; Genzel, Y.; Reichl, U.: Process intensification of yellow fever virus and Zika virus production by perfusion bioreactors. 25th ESACT Meeting, Lausanne, Switzerland (2017)
Poster
Nikolay, A.; Castilho, L.; Genzel, Y.; Reichl, U.: Production of yellow fever virus and Zika virus in perfusion bioreactors. DECHEMA Himmelfahrtstagung "Models for Developing and Optimising Biotech Production", Neu-Ulm, Germany (2017)
2016
Poster
Nikolay, A.; Castilho, L.; Tanuri, A.; Reichl, U.; Genzel, Y.: Propagation of Brazilian Zika virus strains in static, microcarrier-based and suspension cultures using BHK and Vero cells. 1st ESACT Frontiers Retreat 2016, Lyon, France (2016)
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